“sb269970 hcl”的搜索结果

产品 251 到 300 共 325个

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  1. CRT0066101 free base

    Catalog No. A22539
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    PRKDs inhibitor
    CRT0066101 is a PRKDs inhibitor. CRT0066101 suppressed the proliferation and migration of four bladder cancer cell lines in vitro. CRT0066101 blocked tumor growth in a mouse flank xenograft model of bladder cancer. 了解更多
  2. MK-8033 hydrochloride

    Catalog No. A22011
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    dual c-Met/Ron inhibitor
    MK8033 Hcl is a novel and specific dual ATP competitive c-Met/Ron inhibitor (IC50=1 nM Wt c-Met) under investigation as a treatment for cancer. 了解更多
  3. 5-Hydroxy Propafenone D5 Hydrochloride

    Catalog No. A21604
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    5-Hydroxy Propafenone D5 Hcl is the deuterium labeled 5-Hydroxy Propafenone. 了解更多
  4. Efonidipine hydrochloride

    Catalog No. A21431
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    dual T-type and L-type calcium channel blocker
    Efonidipine Hcl (NZ-105) is a dual T-type and L-type calcium channel blocker (CCB). 了解更多
  5. Heptaminol hydrochloride

    Catalog No. A18165
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    Heptaminol hydrochloride is an amino alcohol used as a myocardial stimulant, vasodilator, and to relieve bronchospasm. Its most common therapeutic use is in orthostatic hypotension. 了解更多
  6. Benfluorex hydrochloride

    Catalog No. A18152
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    HNF4α) activator
    Benfluorex hydrochloride (JP-992 hydrochloride) is a hepatic nuclear factor 4 alpha (HNF4α) activator. 了解更多
  7. Piperidolate hydrochloride

    Catalog No. A18144
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    antimuscarinic
    Piperidolate hydrochloride is an antimuscarinic, Also a potential inhibitor of human glutathione transferase P1-1. 了解更多
  8. Metoclopramide hydrochloride hydrate

    Catalog No. A18072
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    Dopamine D2 antagonist
    Metoclopramide hydrochloride hydrate is a dopamine D2 antagonist that is used as an antiemetic. 了解更多
  9. Metipranolol hydrochloride

    Catalog No. A18064
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    β-adrenergic receptor antagonist
    Metipranolol (hydrochloride) is a non-selective β-adrenergic receptor (β-AR) antagonist. Formulations containing metipranolol have been used in the treatment of elevated IOP in patients with ocular hypertension or glaucoma. 了解更多
  10. Mecamylamine Hydrochloride

    Catalog No. A17884
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    nAChR antagonist
    Mecamylamine hydrochloride is a nAChR antagonist previously used to treat hypertension. It displays a wide variety of activities, including reducing depression-like behaviors in subjects with Tourette's syndrome and improving rates of smoking cessation. 了解更多
  11. Moxisylyte hydrochloride

    Catalog No. A17725
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    alpha-adrenergic blocking agent
    Moxisylyte hydrochloride is an alpha-adrenergic blocking agent that is used in Raynaud's disease. It is also used locally in the eye to reverse the mydriasis caused by phenylephrine and other sympathomimetic agents. 了解更多
  12. Rimantadine Hydrochloride

    Catalog No. A17649
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    antiviral drug
    Rimantadine is an orally administered antiviral drug used to treat, and in rare cases prevent, influenzavirus A infection. 了解更多
  13. Promazine hydrochloride

    Catalog No. A17638
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    D2DR inhibitor
    Promazine Hydrochloride is a phenothiazine compound and D2DR inhibitor. Promazine Hydrochloride has been employed in studies investigating dopamine-stimulated glycosylation of brain proteins in vitro. It has actions similar to chlorpromazine but with less antipsychotic activity. 了解更多
  14. Lincomycin Hydrochloride Monohydrate

    Catalog No. A17584
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    Antibacterial agent
    Lincomycin hydrochloride is a peptidyl transferase and protein translation inhibitor used to treat bacterial infections. It also inhibits growth of plasmodium. 了解更多
  15. Fendiline hydrochloride

    Catalog No. A17575
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    Calcium channel blocker
    Fendiline hydrochloride is a nonselective calcium channel blocker. 了解更多
  16. AX-024 hydrochloride

    Catalog No. A18332
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    TNF receptor inhibitor
    AX-024 is an orally available inhibitor of the TCR-Nck interaction that selectively inhibits TCR-triggered T cell activation (IC50 value 1 nM). Inhibiting an immediate TCR signal has promise for treating a broad spectrum of human T cell-mediated autoimmune and inflammatory diseases. 了解更多
  17. Pargyline hydrochloride

    Catalog No. A17288
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    MAO inhibitor
    Pargyline hydrochloride is an irreversible inhibitor of monoamine oxidase (MAO) that is used clinically to treat moderate hypertension. 了解更多
  18. Cefepime Dihydrochloride Monohydrate

    Catalog No. A17272
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    Cefepime Dihydrochloride Monohydrate is a broad-spectrum cephalosporin with enhanced coverage against Gram-positive and Gram-negative bacteria. 了解更多
  19. Piperoxan hydrochloride

    Catalog No. A18336
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    α2 adrenoceptor antagonist
    Piperoxan hydrochloride is an α2 adrenoceptor antagonist. 了解更多
  20. Robenidine Hydrochloride

    Catalog No. A16991
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    Antibiotic
    Robenidine Hydrochloride是一种用于控制球虫病的抗生素,球虫病是一种破坏家禽的原生动物感染。 了解更多
  21. Pitofenone Hydrochloride

    Catalog No. A17053
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    Antispasmodic Agent
    Pitofenone Hydrochloride是抗痉化合物。它是乙酰胆碱酯酶活性的有效抑制剂。 了解更多
  22. ASTX-660

    Catalog No. A16996
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    XIAP 抑制剂
    ASTX660是X染色体连锁的凋亡蛋白抑制剂(XIAP)和细胞IAP 1(cIAP1)的口服生物利用型非拟肽拮抗剂,具有潜在的抗肿瘤和促凋亡活性。1799328-86-1 (free base) 1799328-50-9 (HCl) 1799328-90-7 (mesylate) 1799328-88-3 (sulfate) 了解更多
  23. Lomerizine dihydrochloride

    Catalog No. A16599
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    L-type 拮抗剂
    Lomerizine dihydrochloride是L型和T型Ca2+通道和TRp5通道的拮抗剂,用于治疗偏头痛和眩晕。 了解更多
  24. AN3365

    Catalog No. A16329
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    leucyl-tRNA synthetase 抑制剂
    AN3365是一种有效的,选择性的亮氨酰tRNA合成酶抑制剂。 了解更多
  25. TGR-1202 hydrochloride (Umbralisib HCl)

    Catalog No. A16278
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    PI3Kδ 抑制剂
    TGR-1202 hydrochloride是一种口服的下一代PI3Kδ抑制剂,在基于酶和细胞的测定中抑制PI3Kδ活性,IC50和EC50值分别为22.2和24.3 nM。 了解更多
  26. BI 1467335 (PXS 4728A)

    Catalog No. A16082
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    SSAO/VAP-1 抑制剂
    BI 1467335 (PXS 4728A)是一种非常有效和高度选择性的化合物,正在开发中,用于治疗心脏代谢疾病,例如肝脏相关疾病非酒精性脂肪性肝炎(NASH)。 了解更多
  27. MRT68921

    Catalog No. A15880
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    Autophagy ULK1/2 抑制剂
    MRT68921是一种有效的双重自噬激酶ULK1/2抑制剂,IC50分别为2.9 nM和1.1 nM。 了解更多
  28. SCH 23390 HCl

    Catalog No. A13066
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    D1/D5 receptor 拮抗剂
    SCH 23390 HCl是一种有效的多巴胺受体拮抗剂(D1和D5受体亚型的Ki值分别为0.2 nM和0.3 nM)。 了解更多
  29. Atrasentan HCl

    Catalog No. A15007
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    Endothelin 拮抗剂 receptor
    Atrasentan hydrochloride是一种开发用于治疗前列腺癌的内皮素拮抗剂受体(IC50 = 0.0551 nM,ETA)。 了解更多
  30. Asenapine HCl

    Catalog No. A15002
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    adrenergic receptor/5-HT receptor 抑制剂
    Asenapine hydrochloride抑制肾上腺素能受体(α1,α2A,α2B,α2C)的Ki为0.25-1.2 nM,还抑制5-HT受体(1A,1B,2A,2B,2C,5A,6、7),Ki为0.03- 4.0 nM。 了解更多
  31. AMD-070 HCl

    Catalog No. A14997
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    CXCR4 拮抗剂
    在CXCR4 125I-SDF抑制结合试验中,AMD-070 HCl是一种有效的选择性CXCR4拮抗剂,IC50值为13 nM,抑制T-4型HIV-1(NL4.3株)在MT-4细胞中的复制和PBMC。 了解更多
  32. YM-155 HCl

    Catalog No. A15284
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    Survivin suppressant
    YM-155 hydrochloride是有效的survivin抑制剂,可抑制Survivin启动子活性,IC50为0.54 nM。 了解更多
  33. Vernakalant HCl

    Catalog No. A15275
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    Ion channel blocker
    Vernakalant hydrochloride是一种研究性混合离子通道阻滞剂,可以以2至5 mg/kg的剂量终止人的急性心房纤颤(AF),并且与现有药物相比,对房颤的选择性更高。在抗心律不齐的治疗中。 了解更多
  34. Vandetanib HCl

    Catalog No. A15271
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    VEGFR 抑制剂
    Vandetanib hydrochloride是一种有效的VEGFR2抑制剂,IC50为40 nM。 了解更多
  35. TG 100801 HCl

    Catalog No. A15261
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    VEGFr2 抑制剂
    TG 100801 HCl是TG 100572(HY-10184)的前药,TG 100572是一种多靶点激酶抑制剂,可抑制选择性生长因子受体酪氨酸激酶和Src家族激酶,IC50值为2/7/2/1/0.5 nM或VEGFR1/VEGFR2/FGFR1/Src/Fyn kianse分别。 了解更多
  36. TG 100572 HCl

    Catalog No. A15260
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    VEGFR2/Src kinase 抑制剂
    TG 100572 HCl是一种多靶点激酶抑制剂,可抑制选择性生长因子受体酪氨酸激酶和Src家族激酶,分别对VEGFR1/VEGFR2/FGFR1/Src/Fyn kianse的IC50值为2/7/2/1/0.5 nM。 了解更多
  37. SB-505124 HCl

    Catalog No. A15232
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    TGF-β Receptors 抑制剂
    SB-505124 Hydrochloride是激活素受体样激酶(ALKS)的抑制剂。 了解更多
  38. SB-408124 HCl

    Catalog No. A15231
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    OX Receptor 拮抗剂
    SB408124 Hydrochloride是OX1受体的非肽拮抗剂,全细胞和膜的Ki分别为57 nM和27 nM。表现出比OX2受体高50倍的选择性。 了解更多
  39. CC-401 hydrochloride

    Catalog No. A15037
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    JNK 抑制剂
    CC-401 hydrochloride是具有潜在抗肿瘤活性的第二代ATP竞争性蒽并吡喃酮c-Jun N末端激酶(JNK)抑制剂。 了解更多
  40. Lycorine chloride

    Catalog No. A14501
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    Lycorine chloride显示抑制病毒蛋白质合成和肽基转移酶中心的作用。 了解更多
  41. Xylazine HCl

    Catalog No. A13434
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    Adrenergic Receptor 激动剂
    Xylazine hydrochloride是α2A-AR、α2B-AR和α2C-AR的活化剂。 了解更多
  42. Nisoxetine hydrochloride

    Catalog No. A13418
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    Noradrenalin re-uptake 抑制剂
    Nisoxetine hydrochloride是去甲肾上腺素转运蛋白的选择性强抑制剂,对一系列其他神经递质受体几乎没有或没有亲和力。Nisoxetine hydrochloride是SLC6A2的抑制剂。 了解更多
  43. Octopamine hydrochloride

    Catalog No. A13419
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    Octopamine hydrochloride是一种无脊椎生物胺神经递质,与去甲肾上腺素相关,是肾上腺素受体激动剂。 了解更多
  44. Tranylcypromine hydrochloride

    Catalog No. A13358
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    LSD1/BHC110 & MAO 抑制剂
    Tranylcypromine hydrochloride是一种非选择性的MAO-A/B抑制剂。 了解更多
  45. Bifemelane HCl

    Catalog No. A13353
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    MAO 抑制剂
    Bifemelane hydrochloride是抗抑郁的MAO抑制剂。逆转丁苯那嗪在小鼠中引起的僵直,并增加MPTP处理的mar猴的自发活动。 了解更多
  46. 5-Aminolevulinic acid hydrochloride

    Catalog No. A10016
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    5-Aminolevulinic acid hydrochloride是天然存在的氨基酸。四吡咯的前体在叶绿素和血红素生物合成中的作用。 了解更多
  47. lorcaserin hydrochloride (APD-356)

    Catalog No. A12598
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    serotonin 2C receptor 激动剂
    lorcaserin hydrochloride (APD-356)是血清素2C受体激动剂,可指示与减少热量饮食和增加体育锻炼以减轻慢性体重成人管理。 了解更多
  48. Tetrahydrozoline Hydrochloride

    Catalog No. A13080
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    Adrenergic Receptor 激动剂
    Tetrahydrozoline Hydrochloride是一种引起结膜血管收缩的α激动剂。 了解更多
  49. Oxymetazoline hydrochloride

    Catalog No. A10686
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    alpha-1 adrenergic 激动剂
    Oxymetazoline是一种选择性的α-1激动剂和部分α-2激动剂局部减充血剂,以盐酸羟甲唑啉的形式使用。 了解更多
  50. Olopatadine hydrochloride

    Catalog No. A10671
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    Olopatadine hydrochloride是一种双重作用的组胺H1受体拮抗剂和肥大细胞稳定剂。 了解更多

产品 251 到 300 共 325个

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