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产品 301 到 350 共 2783个

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  1. GR79236

    Catalog No. A20745
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    adenosine A1 receptor agonist
    GR79236 is a highly potent and selective adenosine A1 receptor agonist (Ki = 3.1 nM) that has analgesic and anti-inflammatory actions in humans and animals. 了解更多
  2. SAH

    Catalog No. A20742
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    METTL3-14 inhibitor
    SAH is an amino acid derivative and a modulartor in several metabolic pathways. It is an intermediate in the synthesis of cysteine and adenosine. SAH is an inhibitor for METTL3-METTL14 heterodimer complex (METTL3-14) with an IC50 of 0.9 ?M. 了解更多
  3. 9-Azido-Neu5DAz

    Catalog No. A20741
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    imaging agent
    9-Azido-Neu5DAz is a non-natural bifunctional carbohydrates as imaging agent. 了解更多
  4. Duocarmycin MA

    Catalog No. A20738
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    antibody drug conjugates (ADCs) toxin
    Duocarmycin MA is an antibody drug conjugates (ADCs) toxin. Duocarmycin is a DNA alkylating agent that binds in the minor groove. Duocarmycin MA can be used against multi-drug resistant cell lines. 了解更多
  5. Fenclozine

    Catalog No. A20733
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    Fenclozine is a non-steroidal antiinflammatory drug extracted from patent WO 2012112690 A2. 了解更多
  6. KB-5246

    Catalog No. A20721
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    KB-5246 is a tetracyclic quinolone and displays antibacterial activities. 了解更多
  7. THS-044

    Catalog No. A20712
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    THS-044 binding stabilizes the HIF2α PAS-B folded state, for regulating HIF2 activity in endogenous and clinical settings. 了解更多
  8. SC-52012

    Catalog No. A20709
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    fibrinogen receptor antagonist
    HY-19163 is an orally active fibrinogen receptor antagonist, with antiplatelet activities. 了解更多
  9. Fezolinetant

    Catalog No. A20706
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    NK3R antagonist
    Fezolinetant is an antagonist of the neurokinin 3 receptor (NK3R), used for the treatment of menopausal hot flushes. 了解更多
  10. L-159282

    Catalog No. A20703
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    nonpeptide angiotensin II receptor antagonist
    L-159282 is a highly potent, orally active, nonpeptide angiotensin II receptor antagonist, with anti-hypertensive activity. 了解更多
  11. S-2474

    Catalog No. A20699
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    COX-2/5-LO inhibitor
    S-2474 is an inhibitor of COX-2 and 5-lipoxygenase (5-LO), with IC50s of 11 nM and 27 μM for COX-2 and COX-1 in human intact cells, and used as a nonsteroidal anti-inflammatory drug. 了解更多
  12. Elisartan

    Catalog No. A20697
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    Elisartan is an orally active non-peptide pro-drug of angiotensin II AT1 receptor antagonist HN-12206, and shows anti-hypertension activities. 了解更多
  13. Setmelanotide

    Catalog No. A20689
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    MC4R agonist
    Setmelanotide (RM-493; BIM-22493; IRC-022493) is a selective melanocortin 4 receptor (MC4R) agonist with EC50s of 0.27 nM and 0.28 nM for human and rat MC4R, respectively. 了解更多
  14. PI3K-IN-6

    Catalog No. A20687
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    PI3K β/δ inhibitor
    PI3K-IN-6 (compound 20a) is an oral active and highly selective phosphoinositide 3-kinase (PI3K) β/δ inhibitor, with IC50 values of 7.8 nM/5.3 nM for PI3K β/δ, respectively. 了解更多
  15. Nigericin sodium salt

    Catalog No. A20681
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    NLRP3 activator
    Nigericin sodium salt is an antibiotic from Streptomyces hygroscopicus that works by acting as an H+, K+, and Pb2+ ionophore, a NLRP3 activator. 了解更多
  16. INO-1001

    Catalog No. A20680
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    PARP inhibitor
    INO-1001 is a potent and selective poly (ADP-ribose) polymerase (PARP) inhibitor. 了解更多
  17. GLP-1R Antagonist 1

    Catalog No. A20679
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    glucagon-like peptide 1 receptor antagonist
    GLP-1R Antagonist 1 (compound 5d) is an orally active, CNS penetrant and non-competitive antagonist of glucagon-like peptide 1 receptor (GLP-1R), with an IC50 of 650 nM. 了解更多
  18. BAL-30072

    Catalog No. A20677
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    BAL-30072, a siderophore sulfactam, is a monocyclic beta-lactam antibiotic, with activity against multiresistant gram-negative bacilli. 了解更多
  19. EED226

    Catalog No. A20673
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    PRC2 inhibitor
    EED226 is a polycomb repressive complex 2 (PRC2) inhibitor, which binds to the K27me3-pocket on embryonic ectoderm development (EED) and shows strong antitumor activity in xenograft mice model. 了解更多
  20. NSC23005 sodium

    Catalog No. A20665
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    p18 inhibitor
    NSC23005 sodium is a novel and effective p18 inhibitor (ED50=5.21 nM) in promoting Hematopoietic stem cells (HSCs) expansion in both murine and human models. 了解更多
  21. F 16915

    Catalog No. A20664
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    F 16915 is a docosahexaenoic acid derivative which can prevent heart failure-induced atrial fibrillation. 了解更多
  22. Aminaftone

    Catalog No. A20656
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    Aminaftone, a derivative of 4-aminobenzoic acid, downregulates endothelin-1 (ET-1) production in vitro by interfering with the transcription of the pre-pro-ET-1 gene. 了解更多
  23. Brilacidin

    Catalog No. A20654
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    Brilacidin is a nonpeptidic anti-infective in a new class of defensin mimetics that is being developed for the treatment of eye infections. 了解更多
  24. Vipivotide tetraxetan Linker

    Catalog No. A20653
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    Vipivotide tetraxetan Linker (PSMA-617 Linker) is a nonclaevable peptide linker for synthesis of Vipivotide tetraxetan (PSMA-617). 了解更多
  25. 6-Amino-5-nitropyridin-2-one

    Catalog No. A20646
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    6-Amino-5-nitropyridin-2-one is a pyridine base and used as a nucleobase of hachimoji DNA, in which it pairs with 5-aza-7-deazaguanine. 了解更多
  26. Acoziborole

    Catalog No. A20642
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    Acoziborole (SCYX-7158) is an effective, safe and orally active treatment for human african trypanosomiasis (HAT). In the T. b. brucei S427 strain, the MIC value for SCYX-7158 is 0.6 ?g/mL. 了解更多
  27. JTK-853

    Catalog No. A20639
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    HCV polymerase inhibitor
    JTK-853 is a novel, non-nucleoside Hepatitis C Virus (HCV) polymerase inhibitor which shows effective antiviral activity in HCV replicon cells with EC50s of 0.38 and 0.035 ?M in genotype 1a H77 and 1b Con1 strains, respectively. 了解更多
  28. ACHN-975

    Catalog No. A20637
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    LpxC inhibitor
    ACHN-975 is a selective LpxC inhibitor, exhibiting a subnanomolar LpxC inhibitory activity and low MIC values (??1 μg/mL) against a wide range of Gram-negative bacteria. 了解更多
  29. Saroglitazar

    Catalog No. A20636
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    PPAR agonist
    Saroglitazar is a novel peroxisome proliferator-activated receptor (PPAR) agonist with predominant PPARα and moderate PPARγ activity with EC50 values of 0.65 pM and 3 nM in HepG2 cells, respectively. 了解更多
  30. Azetidine-2-carboxylic acid

    Catalog No. A20628
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    Azetidine-2-carboxylic acid is a non proteinogenic amino acid homologue of proline. Found in common beets. Azetidine-2-carboxylic acid can be misincorporated into proteins in place of proline in many species, including humans. Toxic and teratogenic agent. 了解更多
  31. XEN907

    Catalog No. A20627
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    NaV1.7 blocker
    XEN907 is a novel spirooxindole NaV1.7 blocker, inhibits hNaV1.7 with IC50 of 3 nM. 了解更多
  32. ATB107

    Catalog No. A20612
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    IGPS inhibitor
    ATB107 is a novel and potent inhibitor of indole-3-glycerol phosphate synthase (IGPS) with a KD of 3 μM. 了解更多
  33. 3-Methylxanthine

    Catalog No. A20609
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    GMP inhibitor
    3-Methylxanthine, a xanthine derivative, is a cyclic guanosine monophosphate (GMP) inhibitor, with an IC50 of 920 μM on guinea-pig isolated trachealis muscle. 了解更多
  34. THZ1-R

    Catalog No. A20606
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    THZ1-R is a non-cysteine reactive analog of THZ1 which displays diminished activity for CDK7 inhibition. THZ1-R binds to CDK7 with a Kd of 142 nM. 了解更多
  35. Monobehenin

    Catalog No. A20603
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    Monobehenin has a strong inhibitory activity toward bacterial biofilm formation. 了解更多
  36. NI-42

    Catalog No. A20599
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    BRD inhibitor
    NI-42 (compound 13-d), a structurally orthogonal chemical probe for the BRPFs, is a biased, potent inhibitor of the BRD of the BRPFs (IC50s of BRPF1/2/3=7.9/48/260 nM; Kds of BRPF1/2/3=40/210/940 nM) with excellent selectivity over nonclass IV BRD proteins. 了解更多
  37. Rodatristat ethyl

    Catalog No. A20593
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    TPH1 Inhibitor
    Rodatristat ethyl (KAR5585) is a first-in-class oral tryptophan hydroxylase 1 (TPH1) Inhibitor with nanomolar in vitro potency. Rodatristat ethyl reduces the level of 5-HT and significantly reduces pulmonary arterial hypertension (PAH). 了解更多
  38. Quinolinic acid

    Catalog No. A20575
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    NMDA receptor agonist
    Quinolinic acid is an endogenous N-methyl-D-aspartate (NMDA) receptor agonist synthesized from L-tryptophan via the kynurenine pathway and thereby has the potential of mediating N-methyl-D-aspartate neuronal damage and dysfunction. 了解更多
  39. D,L-3-Indolylglycine

    Catalog No. A20574
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    D,L-3-Indolylglycine is an unnatural amino acid that is very similar to Tryptophan, with the indole moiety directly attached to the α-position. 了解更多
  40. Allopurinol riboside

    Catalog No. A20572
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    Allopurinol riboside, a metabolite of allopurinol, shows potent activities against parasites. 了解更多
  41. FTIDC

    Catalog No. A20554
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    mGluR 1 antagonist
    FTIDC is an orally active, noncompetitive, selective allosteric metabotropic glutamate receptor (mGluR) 1 antagonist with an IC50 of 5.8 nM for human mGluR1a. 了解更多
  42. 6-Maleimidohexanoic acid N-hydroxysuccinimide ester

    Catalog No. A20551
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    6-Maleimidohexanoic acid N-hydroxysuccinimide ester(ECMS) is a useful protective group in antibody drug conjugates. 了解更多
  43. (S)-MCPG

    Catalog No. A20549
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    group I/group II mGluR antagonist
    (S)-MCPG is the active isomer of (RS)-MCPG (Cat. No. HY-100371), non-selective group I/group II metabotropic glutamate receptor antagonist. 了解更多
  44. Mal-amido-PEG8-C2-acid

    Catalog No. A20548
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    nonclaevable ADC linker
    Mal-amido-PEG8-C2-acid (example 142) is a nonclaevable ADC linker, extracted from patent US2018339985. 了解更多
  45. N-(5-Aminopentyl)acetamide

    Catalog No. A20547
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    N-(5-Aminopentyl)acetamide is the acetylated form of the polyamine cadaverine. 了解更多
  46. 3-Bromo-7-nitroindazole

    Catalog No. A20544
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    nNOS inhibitor
    3-Bromo-7-nitroindazole is a more potent and selective inhibitor of neuronal nitric oxide synthase (nNOS) than eNOS or inducible nitric oxide synthase (iNOS). 了解更多
  47. DL-Homocysteine thiolactone hydrochloride

    Catalog No. A20543
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    DL-Homocysteine thiolactone hydrochloride is a cyclic amino acid derivative that exhibits root-growth inhibitory activity. 了解更多
  48. Naltrindole hydrochloride

    Catalog No. A20541
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    δ opioid receptor antagonist
    Naltrindole hydrochloride is a highly potent and selective non-peptide δ opioid receptor antagonist with a Ki of 0.02 nM. 了解更多
  49. MMAF-OMe

    Catalog No. A20540
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    antitubulin agent
    MMAF-Ome, an antitubulin agent, belongs to ADC. 了解更多
  50. T807

    Catalog No. A20538
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    PET tracer
    T807 a novel tau positron emission tomography (PET) tracer. 了解更多

产品 301 到 350 共 2783个

每页
页面:
  1. 5
  2. 6
  3. 7
  4. 8
  5. 9

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