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Eniluracil
Catalog No. A21548 dihydropyrimidine dehydrogenase inhibitorEniluracil (5-Ethynyluracil), a uracil analogue and a mechanism-based irreversible inhibitor of dihydropyrimidine dehydrogenase (DPD), increases the oral bioavailability of 5-fluorouracil (5-FU) to 100%, facilitating uniform absorption and predictable toxicity. 了解更多 -
Vofopitant dihydrochloride
Catalog No. A21543 NK1 receptor antagonistVofopitant dihydrochloride (GR 205171A) is a potent, selective and orally available tachykinin neurokinin 1(NK1) receptor antagonist. 了解更多 -
Genz-123346
Catalog No. A21536 glucosylceramide synthase inhibitorGenz-123346 is a potent, orally available glucosylceramide synthase inhibitor. 了解更多 -
RGX-104 free Acid
Catalog No. A21513 LXR agonistRGX-104 free Acid is an orally bioavailable and potent liver-X nuclear hormone receptor (LXR) agonist that modulates innate immunity via transcriptional activation of the ApoE gene. 了解更多 -
Amuvatinib hydrochloride
Catalog No. A21503 multi-targeted tyrosine kinase inhibitorAmuvatinib hydrochloride (MP470 hydrochloride) is an orally bioavailable multi-targeted tyrosine kinase inhibitor with potent activity against mutant c-Kit, PDGFRα, Flt3, c-Met and c-Ret. 了解更多 -
Naspm trihydrochloride
Catalog No. A21437 CP-AMPA receptors antagonistNaspm trihydrochloride (1-Naphthylacetyl spermine trihydrochloride), a synthetic analogue of Joro spider toxin, is a calcium permeable AMPA (CP-AMPA) receptors antagonist. 了解更多 -
Masupirdine mesylate
Catalog No. A21409 5-HT6 receptor antagonistMasupirdine mesylate (SUVN-502 mesylate) is a potent, selective, orally bioavailable, and brain penetrant 5-HT6 receptor antagonist (Ki of 2.04 nM for human 5-HT6 receptor). 了解更多 -
Raphin1 acetate
Catalog No. A21373 PPP1R15B inhibitorRaphin1 acetate is an orally bioavailable, selective inhibitor of the regulatory phosphatase PPP1R15B (R15B). 了解更多 -
SB-277011 dihydrochloride
Catalog No. A21353 dopamine D3 receptor antagonistSB-277011 dihydrochloride (SB-277011A dihydrochloride) is a potent, selective, orally bioavailable and brain penetrate dopamine D3 receptor antagonist, with pKis of 8.0, 6.0, <5.2 and 5.9 for D3, D2, 5-HT1B, and 5-HT1D receptors, respectively. 了解更多 -
Tipelukast
Catalog No. A21249 leukotriene receptor antagonistTipelukast (KCA 757) is a sulfidopeptide leukotriene receptor antagonist, an orally bioavailable anti-inflammatory agent and used for the treatment of asthma. 了解更多 -
Basimglurant
Catalog No. A21225 mGlu5 negative allosteric modulatorBasimglurant (RG7090) is a potent, selective and orally available mGlu5 negative allosteric modulator with a Kd of 1.1 nM. 了解更多 -
L-371,257
Catalog No. A21219 oxytocin receptor antagonistL-371,257 is an orally bioavailable, non-blood-brain barrier penetrant, selective and competitive antagonist of oxytocin receptor (pA2=8.4) with high affinity at both the oxytocin receptor (Ki=19 nM) and vasopressin V1a receptor (Ki=3.7 nM). 了解更多 -
Indeglitazar
Catalog No. A21148 PPAR agonistIndeglitazar is an orally available peroxisome proliferator-activated receptor (PPAR) pan-agonist for all three PPAR subtypes alpha (α), delta (δ) and gamma (γ). 了解更多 -
Ropidoxuridine
Catalog No. A21128 Ropidoxuridine (IPdR) is a novel orally available, halogenated thymidine analog and is a potential radiosensitizer for use in human tumors. 了解更多 -
5(6)-Carboxyfluorescein
Catalog No. A21120 5(6)-Carboxyfluorescein contains a carboxylic acid that can be used to react with primary amines via carbodiimide activation of the carboxylic acid; cell-impermeant 5,6-FAM can also be used as a nonfixable polar tracer to investigate fusion, lysis and gap-junctional communication and to detect changes in cell or liposome volume. 了解更多 -
Valifenalate
Catalog No. A21111 Valifenalate(IR5885; Valiphenal), which is approved for application on high-value crops such as grapes, tomatoes and other vegetables, is effective against various types of mildew and is currently marketed primarily under the Valis moniker; insecticide agent. 了解更多 -
Galidesivir hydrochloride
Catalog No. A20930 RdRp inhibitorGalidesivir hydrochloride (BCX 4430 hydrochloride) is a viral RNA-dependent RNA polymerase (RdRp) inhibitor; demonstrated broad-spectrum activity in multiple viruses and a favorable preliminary preclinical safety profile. 了解更多 -
Forodesine
Catalog No. A20903 PNP inhibitorForodesine(BCX-1777 freebase; Immucillin-H) is an orally bioavailable PNP inhibitor with picomolar potency; induces apoptosis, mainly in T cells. 了解更多 -
10-Oxo Docetaxel
Catalog No. A20899 10-Oxo Docetaxel (Docetaxel Impurity 1) is a novel taxoid having remarkable anti-tumor properties and a Docetaxel intermediate. 了解更多 -
α-Tocopherol phosphate
Catalog No. A20866 α-Tocopherol phosphate is the compound demonstrating the highest vitamin E activity, which is available both in its natural form as RRR-alpha-tocopherol isolated from plant sources. 了解更多 -
Edasalonexent
Catalog No. A20853 NF-κB inhibitorEdasalonexent (CAT-1004) is an orally bioavailable NF-κB inhibitor. 了解更多 -
Tafamidis meglumine
Catalog No. A18045 transthyretin (TTR) stabilizerTafamidis meglumine (Fx-1006A) is a potent and selective transthyretin (TTR) stabilizer, shows comparable potency and efficacy to the mutumant homotetramers V30M-TTR, V122I-TTR and wild type WT-TTR, with EC50s of 2.7-3.2 μM. 了解更多 -
Hydrocortisone buteprate
Catalog No. A18019 Hydrocortisone buteprate (Hydrocortisone probutate) is a medium potent, non-halogenated double-ester of hydrocortisone with a favorable benefit/risk ratio for the treatment of inflammatory skin disorders. 了解更多 -
Niraparib hydrochloride
Catalog No. A18018 PARP1 and PARP2 inhibitorNiraparib hydrochloride (MK-4827 hydrochloride) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with IC50s of 3.8 and 2.1 nM, respectively. 了解更多 -
Alectinib Hydrochloride
Catalog No. A18000 ALK inhibitorAlectinib Hydrochloride (CH5424802 Hydrochloride; RO5424802 Hydrochloride; AF-802 Hydrochloride) is a potent, selective, and orally available ALK inhibitor with an IC50 of 1.9 nM and a Kd value of 2.4 nM (in an ATP-competitive manner), and also inhibits ALK F1174L and ALK R1275Q with IC50s of 1 nM and 3.5 nM, respectively. 了解更多
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