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Homotaurine
Catalog No. A17944 GABA receptor agonistTramiprosate, also known as homotaurine, is a gamma-Aminobutyric acid (GABA) receptor agonist and a glycosaminoglycan mimetic used in the treatment of Alzheimer's disease. 了解更多 -
Brimonidine
Catalog No. A17899 α2-adrenergic receptor agonistBrimonidine (UK 14304) is a full α2-adrenergic receptor (α2-AR) agonist. 了解更多 -
Alprenolol hydrochloride
Catalog No. A17781 5-HT1A receptor antagonistAlprenolol (hydrochloride) is a non-selective beta blocker as well as 5-HT1A receptor antagonist. 了解更多 -
Doxazosin
Catalog No. A17779 α-1 adrenergic receptor blockerDoxazosin is an α-1 adrenergic receptor blocker that inhibits the binding of norepinephrine, which is released from sympathetic nerve terminals, to the α-1 receptors on the membrane of vascular smooth muscle cells. Blockages of the alpha-1 adrenergic action on the vascular smooth muscles lead to a decrease in vascular resistance and antihypertensive activity. 了解更多 -
Acrivastine
Catalog No. A17746 Histamine 1 receptor antagonistAcrivastine (BW825C) is a short acting histamine 1 receptor antagonist for the treatment of allergic rhinitis. 了解更多 -
Dolasetron Mesylate
Catalog No. A17729 5-HT3 receptor antagonistDolasetron mesylate is a selective 5-HT3 receptor antagonist. 了解更多 -
Hydroxyzine pamoate
Catalog No. A17712 Histamine H1 receptor antagonistHydroxyzine pamoate is an histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIRIZINE, it does cause drowsiness. 了解更多 -
Dolasetron
Catalog No. A17595 5-HT3 receptor antagonistDolasetron is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy. Its main effect is to reduce the activity of the vagus nerve, which is a nerve that activates the vomiting center in the medulla oblongata. It does not have much antiemetic effect when symptoms are due to motion sickness. 了解更多 -
Pyridoxal phosphate
Catalog No. A17592 Purinergic P2 receptor antagonistPyridoxyl phosphate is a purinergic P2 receptor antagonist potentially for the treatment of tardive dyskinesia 了解更多 -
Melitracen hydrochloride
Catalog No. A17494 dopamine D1/2 receptor antagonistMelitracen HCl ia potential dopamine D1/2 receptor antagonist used to treat depression. It is often co-administered with flupenthixol as a treatment for trigeminal neuralgia. It does not effect cardiovascular function. 了解更多 -
Mephenesin
Catalog No. A17493 NMDA receptor antagonistMephenesin is an NMDA receptor antagonist, is a centrally acting muscle relaxant. 了解更多 -
Levocetirizine Dihydrochloride
Catalog No. A17440 L-isomer of cetirizine and histamine H1 receptor antagonistLevocetirizine dihydrochloride is a L-isomer of cetirizine and histamine H1 receptor antagonist. It incrases levels of CD4+ CD25+ T cells and decreases levels of eosinophils, decreasing allergy symptoms. 了解更多 -
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最新产品
Fevipiprant
Catalog No. A17244 CRTh2 receptor antagonistFevipiprant, also known as NVP-QAW039 or QAW039, is an oral active and potent CRTh2 receptor antagonist and potentially useful for asthma treatment. 了解更多 -
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Nifenalol HCl
Catalog No. A17246 beta-adrenergic receptor antagonistNifenalol, also known as INPEA, is a new beta-adrenergic receptor antagonist. 了解更多 -
MRE-269 (ACT-333679)
Catalog No. A18322 selective IP receptor agonistMRE-269 is an active metabolite of selexipag, and acts as a selective IP receptor agonist. 了解更多 -
Terfenadine
Catalog No. A17373 H1 histamine receptor antagonistTerfenadine ((??)-Terfenadine) is a potent open-channel blocker of hERG with an IC50 of 204 nM. Terfenadine, an H1 histamine receptor antagonist, acts as a potent apoptosis inducer in melanoma cells through modulation of Ca2+ homeostasis. Terfenadine induces ROS-dependent apoptosis, simultaneously activates Caspase-4, -2, -9 and induces p73, Noxa. 了解更多 -
Tasimelteon
Catalog No. A17351 MT1 and MT2 receptor agonistTasimelteon is a melatonin MT1 and MT2 receptor agonist. 了解更多 -
Spironolactone
Catalog No. A17345 Androgen receptor antagonistSpironolactone is a potent antagonist of the androgen receptor. 了解更多 -
Methacholine chloride
Catalog No. A17285 Muscarinic receptor agonistMethacholine chloride is a synthetic choline ester that acts as a non-selective muscarinic receptor agonist in the parasympathetic nervous system. 了解更多 -
Eptapirone (F-11440)
Catalog No. A18338 5-HT1A receptor agonistEptapirone is a potent, selective, high efficacy 5-HT1A receptor agonist with marked anxiolytic and antidepressant potential. The affinity of F 11440 for 5-HT1A binding sites (pKi, 8.33) was higher than that of buspirone (pKi, 7.50), and somewhat lower than that of flesinoxan (pKi, 8.91). In vivo, F 11440 was 4- to 20-fold more potent than flesinoxan, and 30- to 60-fold more potent than buspirone. 了解更多 -
Asenapine HCl
Catalog No. A15002 adrenergic receptor/5-HT receptor 抑制剂Asenapine hydrochloride抑制肾上腺素能受体（α1，α2A，α2B，α2C）的Ki为0.25-1.2 nM，还抑制5-HT受体（1A，1B，2A，2B，2C，5A，6、7），Ki为0.03- 4.0 nM。 了解更多 -
Fexofenadine HCl
Catalog No. A11859 COX 抑制剂/histamine H1 receptor 激动剂Fexofenadine Hydrochloride是一种抗组胺药，可抑制Cox-1，Cox-2，并且是组胺H1受体激动剂，IC50为246 nM。 了解更多 -
Hypotaurine
Catalog No. A20590 Hypotaurine (2-aminoethanesulfinic acid), an intermediate in taurine biosynthesis from cysteine in astrocytes, is an endogenous inhibitory amino acid of the glycine receptor. 了解更多 -
GSK2983559 free acid
Catalog No. A22272 RIP2 kinase inhibitorGSK2983559 free acid (compound 3) is a potent, specific and oral bioavailable receptor interacting protein 2 (RIP2) kinase inhibitor. 了解更多 -
Ferulic acid sodium
Catalog No. A22310 FGFR1 inhibitorFerulic acid sodium is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC50s of 3.78 and 12.5 μM for FGFR1 and FGFR2, respectively. 了解更多 -
IRAK4-IN-4
Catalog No. A22333 IRAK4 inhibitorIRAK4-IN-4 is an interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor extracted from patent CN107163044A, Compound15, has an IC50 of 2.8 nM. 了解更多 -
Tirabrutinib hydrochloride
Catalog No. A22375 BTK inhibitorTirabrutinib (ONO-4059) hydrochloride is a selective and novel inhibitor of BTK with IC50 2.2 nm, Tirabrutinib binds to BTK within B cells, thereby preventing B-cell receptor signaling and impeding B-cell development. 了解更多 -
Emamectin Benzoate
Catalog No. A22417 nervoussystem toxicantEmamectin Benzoate (MK-244) is an orally active nervoussystem toxicant by binding g-aminobutyric (GABA) receptor in insects. 了解更多 -
DIM-C-pPhOH
Catalog No. A22424 -
(S,R,S)-AHPC free base
Catalog No. A22481 (S,R,S)-AHPC , also known as also known as MDK7526; VHL Ligand 1; Protein degrader 1, is a potent and selective protein degrader. MDK7526 is potential useful for the targeted degradation of the androgen receptor. 了解更多 -
Caroverine HCl
Catalog No. A22495 Caroverine hydrochloride is a potent, competitive and reversible antagonist of NMDA and AMPA glutamate receptor. Caroverine hydrochloride is also an antioxidant and calcium-blocking agent that exhibits vasorelaxant action. Caroverine hydrochloride can be used for the research of inner ear tinnitus. 了解更多
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