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Telratolimod
Catalog No. A20289 TLR7/8 agonistTelratolimod is a toll like receptors 7/8 (TLR7/8) agonist, with antitumor activity. 了解更多 -
SNAP 94847
Catalog No. A19925 MCHR1 antagonistSNAP 94847 is a novel, high affinity selective melanin-concentrating hormonereceptor1 (MCHR1) antagonist with (Ki= 2.2 nM, Kd=530 pM), it displays >80-fold and >500-fold selectivity over MCHα1A and MCHD2 receptors respectively. 了解更多 -
Ramelteon metabolite M-II
Catalog No. A19921 melatonin agonistRamelteon metabolite M-II is the major metabolite of Ramelteon, with IC50s of 208 pM, 1470 pM for human melatonin receptors (MT1 or MT2). Ramelteon is a selective melatonin agonist. 了解更多 -
GR 159897
Catalog No. A19862 NK2 antagonistGR 159897 is a highly potent, selective, competitive, brain-penetrated non-peptide antagonist at tachykinin NK2 receptors, inhibits binding of [3H]GR100679 to hNK2-CHO cells and rat colon membranes with pKis of 9.51 and 10, respectively. Antagonizes bronchoconstriction, with anxiolytic-like activity. 了解更多 -
Barnidipine hydrochloride
Catalog No. A19280 L-type calcium antagonistBarnidipine hydrochloride (Mepirodipine hydrochloride) is an L-type calcium antagonist (CaA) with high affinity for [3H] initrendipine binding sites (Ki=0.21 nmol/l), has selective action against CaA receptors. 了解更多 -
Pasireotide L-aspartate salt
Catalog No. A18244 Pasireotide(SOM 230) is a stable cyclohexapeptide somatostatin mimic that exhibits unique high-affinity binding to human somatostatin receptors (subtypes sst1/2/3/4/5, pKi=8.2/9.0/9.1/<7.0/9.9 respectively). 了解更多 -
Pasireotide
Catalog No. A21304 Pasireotide(SOM 230) is a stable cyclohexapeptide somatostatin mimic that exhibits unique high-affinity binding to human somatostatin receptors (subtypes sst1/2/3/4/5, pKi=8.2/9.0/9.1/<7.0/9.9 respectively). 了解更多 -
L-Theanine
Catalog No. A21167 L-Theanine (L-Glutamic Acid γ-ethyl amide) is a non-protein amino acid contained in green tea leaves, which blocks the binding of L-glutamic acid to glutamate receptors in the brain, and with neuroprotective and anti-oxidative activities. 了解更多 -
Gemilukast
Catalog No. A21021 CysLT1/CysLT2 antagonistGemilukast is an orally active and potent dual cysteinyl leukotriene 1 and 2 receptors (CysLT1 and CysLT2) antagonist, with IC50s of 1.7, 25 nM for human CysLT1 and CysLT2, respectively. 了解更多 -
all-trans-4-Oxoretinoic acid
Catalog No. A21978 all-trans-4-Oxoretinoic acid, an active metabolite of vitamin A, induces gene transcription via binding to nuclear retinoic acid receptors (RARs). 了解更多 -
Minodronic acid
Catalog No. A21975 purinergic P2X2/3 receptors antagonistMinodronic acid (YM-529) is an antagonist of purinergic P2X2/3 receptors involved in pain. 了解更多 -
(S)-Willardiine
Catalog No. A21957 AMPA/kainate receptors agonist(S)-Willardiine is a potent agonist of AMPA/kainate receptors with EC50 of 44.8 uM. 了解更多 -
ITI214 free base
Catalog No. A21947 picomolar PDE1 inhibitorITI-214 (free base) is a picomolar PDE1 inhibitor with excellent selectivity against other PDE family members and against a panel of enzymes, receptors, transporters, and ion channels, exhibits potent PDE1 inhibitory activity (Ki = 58 pM). 了解更多 -
Barnidipine
Catalog No. A21940 L-type calcium antagonistBarnidipine (Mepirodipine) is an L-type calcium antagonist (CaA) with high affinity for [3H] initrendipine binding sites (Ki=0.21 nmol/l), has selective action against CaA receptors. 了解更多 -
JTV-519 free base
Catalog No. A21846 Ca2+-dependent blockerTV-519 free base (K201 free base) is a Ca2+-dependent blocker of sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA) and a partial agonist of ryanodine receptors in striated muscle. Antiarrhythmic and cardioprotective properties. 了解更多 -
Anandamide
Catalog No. A21835 immune modulatorAnandamide is an immune modulator in the central nervous system acts via not only cannabinoid receptors (CB1 and CB2) but also other targets (e.g., GPR18/GPR55). 了解更多 -
Gaboxadol hydrochloride
Catalog No. A21730 GABAA receptors agonistGaboxadol hydrochloride (Lu 02-030 hydrochloride) is a selective agonist at GABAA receptors that contain α4-δ subunits, and has anxiolytic and sedative effects. 了解更多 -
Mibampator
Catalog No. A21717 AMPA receptors potentiatorMibampator (LY451395) is a potent and highly selective potentiator of the AMPA receptors. 了解更多 -
Naspm trihydrochloride
Catalog No. A21437 CP-AMPA receptors antagonistNaspm trihydrochloride (1-Naphthylacetyl spermine trihydrochloride), a synthetic analogue of Joro spider toxin, is a calcium permeable AMPA (CP-AMPA) receptors antagonist. 了解更多 -
Impurity F of Calcipotriol
Catalog No. A21215 Impurity F of Calcipotriol; Calcipotriol (MC 903; Calcipotriene) is a ligand of VDR-like receptors. 了解更多 -
24R-Calcipotriol
Catalog No. A21213 24R-Calcipotriol(PRI 2202) is an impurity of Calcipotriol; Calcipotriol (MC 903; Calcipotriene) is a ligand of VDR-like receptors. 了解更多 -
O-Phospho-L-serine
Catalog No. A21159 group III mGluR receptors agonistO-Phospho-L-serine is the immediate precursor to L-serine in the serine synthesis pathway, and an agonist at the group III mGluR receptors (mGluR4, mGluR6, mGluR7, and mGluR8); O-Phospho-L-serine also acts as a weak antagonist for mGluR1 and a potent antagonist for mGluR2. 了解更多 -
Carbetocin
Catalog No. A18080 peripheral oxytocin receptors agonistCarbetocin (Lonactene; Duratocin) is an obstetric drug used to control postpartum hemorrhage and bleeding after giving birth; an agonist at peripheral oxytocin receptors. 了解更多 -
Pirmenol hydrochloride
Catalog No. A18009 Pirmenol hydrochloride inhibits IK.ACh by blocking muscarinic receptors. The IC50 of Pirmenol for inhibition of Carbachol-induced IK.ACh is 0.1 μM. 了解更多 -
Terlipressin
Catalog No. A17990 vasoconstrictorTerlipressin is a potent vasoconstrictor that acts via V1 receptors on arteriolar smooth muscle cells. 了解更多 -
L-Glutamic acid monosodium salt
Catalog No. A16591 excitatory transmitter/agonistL-Glutamic acid monosodium salt acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). (S)-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals. 了解更多 -
(S)-Glutamic acid
Catalog No. A15458 glutamate receptors agonist(S)-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). 了解更多 -
JDTic dihydrochloride
Catalog No. A11469 KOR antagonistJDTic (dihydrochloride) is a potent antagonist of kappa-opioid receptors (KOR), blocking the κ-agonist U50, 488-induced antinociception. 了解更多 -
Donitriptan
Catalog No. A13145 5-HT1B/1D receptors agonistDonitriptan is a potent, high efficacy agonist at 5-HT1B/1D receptors with pKis of 9.4 and 9.3, respectively. 了解更多 -
Bamirastine
Catalog No. A13325 Bamirastine inhibits ligand binding to recombinant human histamine H1 receptors (rhH1R) with an IC50 value of 17.3 nM. 了解更多 -
Imidazoleacetic acid
Catalog No. A19094 Imidazoleacetic acid is an endogenous ligand that stimulates imidazole receptors. 了解更多 -
Almitrine mesylate
Catalog No. A18020 Peripheral chemoreceptor agonistAlmitrine mesylate, a peripheral chemoreceptor agonist, inhibits selectively the Ca2+-dependent K+ channel. 了解更多
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