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(20S)-Protopanaxatriol
Catalog No. A15649 LXRα inhibitor(20S)-Protopanaxatriol is a metabolite of ginsenoside, works through the glucocorticoid receptor (GR) and oestrogen receptor (ER), and is also a LXRα inhibitor. (20S)-Protopanaxatriol shows a broad spectrum of antitumor effects. 了解更多 -
D,L-3-Indolylglycine
Catalog No. A20574 D,L-3-Indolylglycine is an unnatural amino acid that is very similar to Tryptophan, with the indole moiety directly attached to the α-position. 了解更多 -
Tiodazosin
Catalog No. A20463 ostsynaptic alpha adrenergic receptor antagonistTiodazosin is a potent competitive postsynaptic alpha adrenergic receptor antagonist. 了解更多 -
AGN 194078
Catalog No. A20387 RARα agonistAGN 194078 is a selective RARα agonist with a Kd and EC50 of 3 and 112 nM, respectively. 了解更多 -
Lidanserin
Catalog No. A20266 5-HT2A/α1-adrenergic receptor antagonistLidanserin is a drug which acts as a combined 5-HT2A and α1-adrenergic receptor antagonist. 了解更多 -
c(phg-isoDGR-(NMe)k)
Catalog No. A20106 α5β1-integrin ligandc(phg-isoDGR-(NMe)k) is a selective and potent α5β1-integrin ligand with an IC50 of 2.9 nM. 了解更多 -
Imiglitazar
Catalog No. A20080 PPARα/ PPARγ1 agonistImiglitazar (TAK559) is a potent and dual human PPARα and PPARγ1 agonist with EC50 values of 67 and 31 nM. 了解更多 -
UDP-GlcNAc Disodium Salt
Catalog No. A19951 OGT donor substrateUDP-GlcNAc Disodium Salt (UDP-α-D-N-Acetylglucosamine Disodium Salt) is a donor substrate of O-GlcNAc transferase (OGT). 了解更多 -
Oleoylethanolamide
Catalog No. A19944 PPAR-α agonistOleoylethanolamide is a high affinity endogenous PPAR-α agonist, which plays an important role in the treatment of obesity and arteriosclerosis. 了解更多 -
PKG drug G1
Catalog No. A19870 PKG drug G1 targets C42 of PKG Iα. PKG drug G1 can couple to vasodilation and blood pressure lowering by a C42 PKG Iα-independent mechanism. 了解更多 -
Zuranolone
Catalog No. A19805 GABAA receptor agonistZuranolone is a potent GABAA receptor agonist with EC50s of 296 and 163 nM for α1β2γ2 and α4β3δ GABAA receptors, respectively. 了解更多 -
Dianicline dihydrochloride
Catalog No. A19775 α4β2 nicotinic acetylcholine receptor partial agonistDianicline dihydrochloride is a α4β2 nicotinic acetylcholine receptor partial agonist, a class of drugs that includes varenicline and cytisine for smoking cessation. 了解更多 -
DIM-C-pPhOCH3
Catalog No. A19708 Nur77 agonistDIM-C-pPhOCH3 is a Nur77 agonist. Nerve growth factor-induced Bα (NGFI-Bα, Nur77) is an orphan nuclear receptor. 了解更多 -
Indanidine
Catalog No. A19673 -
5,6,7-Trimethoxyflavone
Catalog No. A19612 p38-α MAPK inhibitor5,6,7-Trimethoxyflavone is a novel p38-α MAPK inhibitor with an anti-inflammatory effect. 5,6,7-Trimethoxyflavone is isolated from several plants including Zeyhera tuberculosa, Callicarpa japonica, and Kickxia lanigera. 了解更多 -
Tedatioxetine hydrobromide
Catalog No. A19418 triple reuptake inhibitor/5-HT2A/5-HT2C/5-HT3/α1A-adrenergic receptor antagonisTedatioxetine hydrobromide acts as a triple reuptake inhibitor and 5-HT2A, 5-HT2C, 5-HT3 and α1A-adrenergic receptor antagonist. 了解更多 -
β-Apo-13-carotenone
Catalog No. A19360 antagonist of RXRαβ-Apo-13-carotenone (D'Orenone) is a naturally occurring β-apocarotenoid functioned as an antagonist of RXRα. 了解更多 -
ONO-8590580
Catalog No. A19337 -
Cyclo(RGDyK)
Catalog No. A21819 αVβ3 integrin inhibitorCyclo(RGDyK) is a potent and selective αVβ3 integrin inhibitor with an IC50 of 20 nM. 了解更多 -
Carotegrast
Catalog No. A21997 α4 integrin receptor inhibitorCarotegrast is an orally available α4 integrin receptor inhibitor with anti-inflammatories activities. 了解更多 -
Ritanserin
Catalog No. A21976 5-HT2 receptor antagonistRitanserin (R 55667) is a highly potent, relatively selective, orally active, long acting antagonist of 5-HT2 receptor, with an IC50 of 0.9 nM, less active on Histamine H1, Dopamine D2, Adrenergic α1, Adrenergic α2 receptors. 了解更多 -
Ralimetinib
Catalog No. A21942 p38 MAPK α/β inhibitorRalimetinib (LY2228820) is a potent and selective, ATP-competitive inhibitor of p38 MAPK α/β, with IC50s of 5.3 and 3.2 nM, respectively. 了解更多 -
BMS-582949 hydrochloride
Catalog No. A21914 p38α MAPK inhibitorBMS-582949 hydrochloride is an orally active and highly selective p38α MAPK inhibitor, with an IC50 of 13 nM. 了解更多 -
MW-150 dihydrochloride dihydrate
Catalog No. A21860 p38α MAPK inhibitorMW-150 dihydrochloride dihydrate (MW01-18-150SRM dihydrochloride dihydrate) is a selective, CNS penetrant, and orally active inhibitor of p38α MAPK with a Ki of 101 nM. 了解更多 -
MW-150 hydrochloride
Catalog No. A21854 p38α MAPK inhibitorMW-150 hydrochloride (MW01-18-150SRM hydrochloride) is a selective, CNS penetrant, and orally active inhibitor of p38α MAPK with a Ki of 101 nM. 了解更多 -
20(S)-Hydroxycholesterol
Catalog No. A21850 Smo allosteric activator20(S)-hydroxyCholesterol (20α-Hydroxycholesterol) is an allosteric activator of the oncoprotein smoothened (Smo) that activates the hedgehog (Hh) signaling pathway with an EC50 of 3 μM in a gene transcription reporter assay using NIH3T3 cells. 了解更多 -
DO34 analog
Catalog No. A21821 triazole DAGL(α) inhibitorDO34 analog is a triazole DAGL(α) inhibitor extracted from patent WO2017096315 A1, compound 100. 了解更多 -
Dehydroaltenusin
Catalog No. A21804 eukaryotic DNA polymerase α inhibitorDehydroaltenusin is a small molecule selective inhibitor of eukaryotic DNA polymerase α, a type of antibiotic produced by a fungus with an IC50 value of 0.68 μM. 了解更多 -
AZD9496 maleate
Catalog No. A21726 estrogen receptor (ERα) antagonistAZD9496 maleate is a potent and selective estrogen receptor (ERα) antagonist with IC50 of 0.28 nM. AZD9496 maleate is an orally bioavailable selective oestrogen receptor degrader (SERD). 了解更多 -
Mirogabalin
Catalog No. A21626 Mirogabalin (DS-5565) is a novel, preferentially selective α2δ-1 ligand characterized by high potency and selectivity to the α2δ-1 subunit of voltage-sensitive calcium channel complexes in the CNS. 了解更多 -
Finasteride acetate
Catalog No. A21537 testosterone 5-alpha-reductase inhibitorFinasteride (acetate) is an orally active testosterone 5-alpha-reductase inhibitor. 了解更多 -
β-Apo-13-carotenone D3
Catalog No. A21462 RXRα antagonistβ-Apo-13-carotenone D3 is the deuterium labeled β-Apo-13-carotenone. β-Apo-13-carotenone (D'Orenone) is a naturally occurring β-apocarotenoid functioned as an antagonist of RXRα. 了解更多 -
PNU-282987 S enantiomer free base
Catalog No. A21459 PNU-282987 S enantiomer free base is the S-enantiomer of PNU-282987 free base. PNU-282987 is an α7 nicotinic acetylcholine receptor (α7 nAChR) agonist. 了解更多 -
CHIR-99021 trihydrochloride
Catalog No. A21436 GSK-3α/β inhibitorCHIR-99021 trihydrochloride (CT99021 trihydrochloride) is a GSK-3α/β inhibitor with IC50 of 10 nM/6.7 nM. 了解更多 -
CHIR-99021 monohydrochloride
Catalog No. A21430 GSK-3α/β inhibitorCHIR-99021 monohydrochloride (CT99021 monohydrochloride) is a GSK-3α/β inhibitor with IC50 of 10 nM/6.7 nM; > 500-fold selectivity for GSK-3 versus its closest homologs CDC2 and ERK2, as well as other protein kinases. 了解更多 -
ATN-161 trifluoroacetate salt
Catalog No. A21412 integrin α5β1 antagonistATN-161 trifluoroacetate salt is a novel integrin α5β1 antagonist, which inhibits angiogenesis and growth of liver metastases in a murine model. 了解更多 -
Peliglitazar racemate
Catalog No. A21411 dual α/γ PPAR activatorPeliglitazar racemate is the racemate of Peliglitazar. Peliglitazar is a novel dual α/γ PPAR activator. 了解更多 -
(Rac)-PT2399
Catalog No. A21376 HIF-2α inhibitor(Rac)-PT2399 (Compound 10e), the racemate of PT2399, acts as a potent and specific hypoxia-inducible factor 2a (HIF-2α) inhibitor with an IC50 of 0.01 μM. 了解更多 -
Atipamezole
Catalog No. A21363 α2-adrenoceptor antagonistAtipamezole is a synthetic α2-adrenoceptor antagonist with a Ki of 1.6 nM. 了解更多
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