“sn 2”的搜索结果

产品 301 到 350 共 17249个

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  1. LMPTP INHIBITOR 1 dihydrochloride

    Catalog No. A22227
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    LMPTP inhibitor
    LMPTP INHIBITOR 1 (dihydrochloride) is a selective inhibitor of low molecular weight protein tyrosine phosphatase (LMPTP), with an IC50 of 0.8 μM LMPTP-A. 了解更多
  2. LY2828360

    Catalog No. A22228
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    cannabinoid (CB2) agonist
    LY2828360 is a slowly acting but efficacious G protein-biased cannabinoid (CB2) agonist, inhibiting cAMP accumulation and activating ERK1/2 signaling. 了解更多
  3. KN-93 phosphate

    Catalog No. A22229
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    membrane-permeant synthetic inhibitor
    KN-93 phosphate is a novel membrane-permeant synthetic inhibitor of purified neuronal CaMK-II, with Ki of 370 nM. 了解更多
  4. LYN-1604 dihydrochloride

    Catalog No. A22230
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    ULK1 activator
    LYN-1604 dihydrochloride is a potent UNC-51-like kinase 1 (ULK1) activator (EC50=18.94 nM) for the research of triple negative breast cancer (TNBC). 了解更多
  5. GNE-490

    Catalog No. A22231
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    pan-PI3K inhibitor
    GNE-490 is a highly selective pan-PI3K inhibitor that demonstrates selectivity over mTOR. 了解更多
  6. Almonertinib

    Catalog No. A22232
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    EGFR inhibitor
    Almonertinib (HS-10296) is an orally available, irreversible, third-generation EGFR tyrosine kinase inhibitor with high selectivity for EGFR-sensitizing and T790M resistance mutations. 了解更多
  7. HQNO

    Catalog No. A22233
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    electron transport chain inhibitor
    HQNO, secreted by P. aeruginosa, is a potent electron transport chain inhibitor with a Kd of 64 nM for complex III. 了解更多
  8. Enocitabine

    Catalog No. A22234
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    DNA replication inhibitor
    Enocitabine is a nucleoside analog, and is a potent DNA replication inhibitor, and a DNA chain terminator. 了解更多
  9. Cl-amidine TFA

    Catalog No. A22235
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    peptidylarginine deminase (PAD) inhibitor
    Cl-amidine TFA is an orally active peptidylarginine deminase (PAD) inhibitor, with IC50 values of 0.8 μM, 6.2 μM and 5.9 μM for PAD1, PAD3, and PAD4, respectively. 了解更多
  10. DS-1001b

    Catalog No. A22236
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    mutant IDH-1 inhibitor
    DS-1001b is a mutant IDH-1 (Isocitrate Dehydrogenase-1) inhibitor extracted from patent WO2016052697A1, Example 168, and has antitumor activity. 了解更多
  11. Taletrectinib

    Catalog No. A22237
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    ROS1/NTRK inhibitor
    Taletrectinib (DS-6051b) is a potent, orally active, and new-generation selective ROS1/NTRK inhibitor. 了解更多
  12. VTP50469

    Catalog No. A22238
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    Menin-MLL interaction inhibitor
    VTP50469 is a potent, highly selective and orally active Menin-MLL interaction inhibitor with a Ki of 104 pM. VTP50469 has potently anti-leukemia activity. 了解更多
  13. LY-3475070

    Catalog No. A22239
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    CD73 Inhibitor
    LY-3475070 is a potent and selective CD73 Inhibitor with IC50 of 28 nM. 了解更多
  14. Mobocertinib succinate

    Catalog No. A22240
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    EGFR/HER2 oncogenic mutants inhibitor
    Mobocertinib succinate (TAK-788 succinate) is a potent and orally active inhibitor of EGFR and HER2 oncogenic mutants, including exon 20 insertions, with selectivity over WT EGFR. Antitumor activity. 了解更多
  15. ML254

    Catalog No. A22242
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    Positive Allosteric Modulators (PAMs)
    ML-254, also known as VU0430644; is Positive Allosteric Modulators (PAMs) of mGlu5 with Competitive MPEP-Site Interaction. 了解更多
  16. VK-II-36

    Catalog No. A22243
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    carvedilol analog
    VK-II-36 is a carvedilol analog that suppresses sarcoplasmic reticulum (SR) Ca(2+) release but does not block the β-receptor. 了解更多
  17. ML-335

    Catalog No. A22244
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    OPRM1(μ-opioid receptor)-OPRD1(δ-opioid receptor) heterodimerization agonist
    ML335 (CYM 51010, CID-23723457) is an agonist for OPRM1(μ-opioid receptor)-OPRD1(δ-opioid receptor) heterodimerization with EC50 of 403 nM demonstrating selectivity over the individual OPRM1 and OPRD1 receptors and the serotonin HT5A receptor with EC50 of 14.9 μM, 1.1 μM, and >40 μM, respectively. 了解更多
  18. CRT5

    Catalog No. A22245
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    PKD inhibitor
    CRT5 (CRT0066051), a pyrazine benzamide, is a potent and selective PKD inhibitor with IC50 of 1 nM, 2 nM, and 1.5 nM for PKD1, PKD2, and PKD3, respectively. 了解更多
  19. TAE-1

    Catalog No. A22246
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    inhibitor of amyloid-β fibril formation and aggregation
    TAE-1 is an inhibitor of amyloid-β fibril formation and aggregation. TAE-1 inhibits cholinesterases AChE and BuChE with IC50 of 0.3 μM and 3.9 μM, respectively. 了解更多
  20. Imidazenil

    Catalog No. A22247
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    GABA-A modulator
    Imidazenil is a GABA-A modulator that blocks the sedative effects without lowering the convulsion threshold. 了解更多
  21. HS-1793

    Catalog No. A22248
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    Anti-tumor inhibitor
    HS-1793 is a resveratrol analogue. HS-1793 downregulates the expression of hypoxia-induced HIF-1 and VEGF and inhibits tumor growth of human breast cancer cells in a nude mouse xenograft model. 了解更多
  22. DD1

    Catalog No. A22249
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    proteasome inhibitor
    DD1 is a proteasome inhibitor that induces human myeloid tumor-selective apoptosis. 了解更多
  23. TSPC (HUN86320)

    Catalog No. A22250
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    inhibitor for GA perception
    TSPC is an inhibitor for GA perception by in vitro and in planta evaluations. 了解更多
  24. ML266

    Catalog No. A22251
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    activator of glucocerebrosidase (GCase)
    ML266 (CID-46943215) is a activator of glucocerebrosidase (GCase) that does not inhibit the enzyme??s action but can still facilitates its translocation to the lysosome. 了解更多
  25. Pitstop 2

    Catalog No. A22252
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    clathrin inhibitor
    Pitstop 2 is a clathrin inhibitor which inhibits clathrin-mediated endocytosis (CME) by associating with the terminal domain of clathrin. 了解更多
  26. Imidacloprid-urea

    Catalog No. A22253
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    marine xenobiotic metabolite
    Imidacloprid-urea with a role as a marine xenobiotic metabolite, is the primary imidacloprid soil metabolite, whereas imidacloprid-olefin is the main plant-relevant metabolite and is more toxic to insects than imidacloprid. 了解更多
  27. AQX-016A

    Catalog No. A22254
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    activator of SHIP-1
    AQX-016A is a potent activator of SHIP-1 that induces apoptosis of the cancer cell lines in vitro in both a time and dose dependant manner. 了解更多
  28. Finasteride Carboxaldehyde

    Catalog No. A22255
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    used for proteomics research
    Finasteride Carboxaldehyde is a metabolite of Finasteride in human bile (M2 metabolite) that can be used for proteomics research. 了解更多
  29. CFI-400945

    Catalog No. A22256
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    PLK4 inhibitor
    CFI-400945 is an orally active, potent and selective polo-like kinase 4(PLK4) inhibitor with Ki value of 0.26 nM. 了解更多
  30. Salvinorin B

    Catalog No. A22257
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    analytical reference material categorized
    Salvinorin B (Item No. 11488) is an analytical reference material categorized as a diterpene. 了解更多
  31. (R)-Propranolol hydrochloride

    Catalog No. A22258
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    β-adrenergic receptor (βAR) antagonist
    (R)-Propranolol hydrochloride is a less active enantiomer of the β-adrenoceptor antagonist propranolol (HY-B0573). Propranolol is a nonselective β-adrenergic receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with Ki values of 1.8 nM and 0.8 nM, respectively. 了解更多
  32. Clenproperol

    Catalog No. A22259
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    β2-adrenergic agonist
    Clenproperol is a β2-adrenergic agonist. 了解更多
  33. Propachlor

    Catalog No. A22260
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    LDH1A1 inhibitor
    Propachlor is a specific ALDH1A1 inhibitor. It is sometimes used as an herbicide. 了解更多
  34. N-(beta-Ketocaproyl)-L-hoMoserine lactone

    Catalog No. A22261
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    autoinducer of P. fischeri luciferase
    N-(beta-ketocaproyl)-L-Homoserine lactone (N-(Ketocaproyl)-L-homoserine lactone, N-(β-Ketocaproyl)-L-hoMoserine lactone) is an autoinducer of P. fischeri luciferase and a component of quorum regulatory sensing. 了解更多
  35. AG-1478 hydrochloride

    Catalog No. A22262
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    EGFR tyrosine kinase inhibitor
    AG-1478 hydrochloride (Tyrphostin AG-1478 hydrochloride) is a selective EGFR tyrosine kinase inhibitor with IC50 of 3 nM. 了解更多
  36. Ferulic acid methyl ester

    Catalog No. A22364
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    antioxidant agent
    Ferulic acid methyl ester (Methyl Ferulate, Methyl 4'-hydroxy-3'-methoxycinnamate) is a lipophilic derivative of ferulic acid, which is a hydroxycinnamic acid that is abundant in plants. It shows the strongest antioxidant activity and can protect against inflammation and cancer. 了解更多
  37. 7-Hydroxy-4H-chromen-4-one

    Catalog No. A22365
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    Src kinase inhibitor
    7-Hydroxychromone is a Src kinase inhibitor with an IC50 of <300 μM. 了解更多
  38. 6-(Dimethylamino)purine

    Catalog No. A22366
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    dual inhibitor of protein kinase and CDK
    6-(Dimethylamino)purine is a dual inhibitor of protein kinase and CDK. 了解更多
  39. Mitapivat

    Catalog No. A22367
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    PKM2 activator
    Mitapivat is a pyruvate kinase isoenzyme M2 (PKM2) activator. 了解更多
  40. Iso-H7 dihydrochloride

    Catalog No. A22368
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    inhibitor of phosphokinase C
    Iso-H7 dihydrochloride is an inhibitor of phosphokinase C. 了解更多
  41. ZD-4190

    Catalog No. A22369
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    VEGFR2 and EGFR signalling inhibitor
    ZD-4190 is a potent, orally available inhibitor of the vascular endothelial cell growth factor receptor 2 (VEGFR2) and of epidermal growth factor receptor (EGFR) signalling, used for the treatment of cancer. 了解更多
  42. PF-562271 hydrochloride

    Catalog No. A22370
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    FAK and Pyk2 kinase inhibitor
    PF-562271 hydrochloride is a potent, ATP-competitive and reversible FAK and Pyk2 kinase inhibitor with IC50s of 1.5 nM and 13 nM, respectively. 了解更多
  43. SAR-020106

    Catalog No. A22371
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    CHK1 inhibitor
    SAR-020106 is an ATP-competitive, potent, and selective CHK1 inhibitor with an IC50 of 13.3 nM for human CHK1. 了解更多
  44. CCT196969

    Catalog No. A22372
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    pan-Raf inhibitor
    CCT196969 is a pan-Raf inhibitor, which inhibits B-Raf, BRafV600E and CRAF with IC50s of 0.1, 0.04, and 0.01 μM, respectively. 了解更多
  45. Nemiralisib

    Catalog No. A22373
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    PI3Kδ inhibitor
    Nemiralisib (GSK2269557 free base) is a potent and highly selective PI3Kδ inhibitor with a pKi of 9.9. 了解更多
  46. NSC12

    Catalog No. A22374
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    antitumor agent
    NSC12 (NSC 172285) is an orally available pan-FGF trap able to inhibit FGF2/FGFR interaction and endowed with promising antitumor activity. 了解更多
  47. Tirabrutinib hydrochloride

    Catalog No. A22375
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    BTK inhibitor
    Tirabrutinib (ONO-4059) hydrochloride is a selective and novel inhibitor of BTK with IC50 2.2 nm, Tirabrutinib binds to BTK within B cells, thereby preventing B-cell receptor signaling and impeding B-cell development. 了解更多
  48. Miransertib hydrochloride

    Catalog No. A22376
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    Akt inhibitor
    Miransertib hydrochloride (ARQ-092 hydrochloride) is a potent, orally active, selective and allosteric Akt inhibitor with IC50s of 2.7 nM, 14 nM and 8.1 nM for Akt1, Akt2, Akt3, respectively. 了解更多
  49. PF-06273340

    Catalog No. A22377
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    pan-Trk inhibitor
    PF-06273340 is a highly potent, kinases elective, well-tolerated pan-Trk inhibitor with IC50 values of 6, 4, 3 nM for TrkA, TrkB, Trk C, respectively. 了解更多
  50. VPS34 inhibitor 1 (Compound 19)

    Catalog No. A22378
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    VPS34 inhibitor
    VPS34 inhibitor 1 (Compound 19, PIK-III analogue) is a potent and selective inhibitor of VPS34 with an IC50 of 15 nM. 了解更多

产品 301 到 350 共 17249个

每页
页面:
  1. 5
  2. 6
  3. 7
  4. 8
  5. 9

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