“glucagon receptor”的搜索结果

产品 351 到 400 共 1712个

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  1. GC 14

    Catalog No. A19928
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    thyroid hormone receptor antagonist
    GC 14 is a selective thyroid hormone receptor antagonist, with IC50 values of 35 nM and 200 nM for hTRβ and hTRα, respectively. 了解更多
  2. N6-Ethyladenosine

    Catalog No. A19918
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    Adenosine receptor agonist
    N6-Ethyladenosine is an adenosine derivative, acts as a Adenosine receptor agonist, with Kis of 4.9 and 4.7 nM for hA1AR and hA3AR, respectively. 了解更多
  3. YM-58790

    Catalog No. A19917
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    M3 muscarinic receptor antagonist
    YM-58790 is a potent antagonist of M3 muscarinic receptor, with Ki of 15 nM. 了解更多
  4. Leelamine hydrochloride

    Catalog No. A19910
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    CB1 agonist
    Leelamine hydrochloride is a tricyclic diterpene molecule that is extracted from the bark of pine trees. Leelamine hydrochloride is a cannabinoid receptor type 1 (CB1) agonist and a inhibitor of SREBP1-regulated fatty acid/lipid synthesis in prostate cancer cells that is not affected by androgen receptor status. 了解更多
  5. (Z)-Guggulsterone

    Catalog No. A19901
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    farnesoid X receptor antagonist
    (Z)-Guggulsterone is a phytosteroid found in the resin of the guggul plant, Commiphora mukul. It acts as an antagonist of the farnesoid X receptor in humans. 了解更多
  6. LM-1484

    Catalog No. A19872
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    CysLT1 receptor antagonist
    LM-1484 is an antagonist of CysLT1 receptor and displays a higher affinity for 3H-LTC4 sites. 了解更多
  7. AZD7594

    Catalog No. A19866
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    glucocorticoid receptor modulator
    AZD7594 is a potent selective nonsteroidal glucocorticoid receptor modulator, with an IC50 of 0.9 nM. 了解更多
  8. Ecastolol

    Catalog No. A19846
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    beta adrenergic receptor antagonist
    Ecastolol is a beta adrenergic receptor antagonist, with antianginal activities. 了解更多
  9. VU0467154

    Catalog No. A19842
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    mAChR modulator
    VU0467154 is a positive allosteric modulator of the M4 muscarinic acetylcholine receptor (mAChR), potentiating the response to ACh with pEC50s of 7.75, 6.2 and 6 for rat, human and cynomolgus monkey M4 receptor, respectively. 了解更多
  10. Zuranolone

    Catalog No. A19805
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    GABAA receptor agonist
    Zuranolone is a potent GABAA receptor agonist with EC50s of 296 and 163 nM for α1β2γ2 and α4β3δ GABAA receptors, respectively. 了解更多
  11. LCB-2853

    Catalog No. A19790
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    TXA2 receptor
    LCB-2853 is an antagonist of thromboxane A2 (TXA2) receptor, with antiplatelet and antithrombotic activities. 了解更多
  12. ACP-105

    Catalog No. A19778
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    androgen receptor modulator
    ACP-105 is an orally available, selective amd potent androgen receptor modulator (SARM), with pEC50s of 9.0 and 9.3 for AR wild type and T877A mutant, respectively. 了解更多
  13. Dianicline dihydrochloride

    Catalog No. A19775
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    α4β2 nicotinic acetylcholine receptor partial agonist
    Dianicline dihydrochloride is a α4β2 nicotinic acetylcholine receptor partial agonist, a class of drugs that includes varenicline and cytisine for smoking cessation. 了解更多
  14. CGRP antagonist 1

    Catalog No. A19760
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    CGRP receptor antagonist
    CGRP antagonist 1 is a highly potent CGRP receptor antagonist with a Ki and IC50 of 35 and 57 nM, respectively. 了解更多
  15. GDC-0927

    Catalog No. A19747
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    estrogen receptor antagonist
    GDC-0927 (SRN-927) is a novel, potent, non-steroidal, orally bioavailable, selective estrogen receptor antagonist. 了解更多
  16. CGP48369

    Catalog No. A19745
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    angiotensin II receptor antagonist
    CGP48369 is a nonpeptidic angiotensin II receptor antagonist, used for anti-hypertensive research. 了解更多
  17. LSZ-102

    Catalog No. A19728
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    estrogen receptor degrader
    LSZ-102 is a potent, orally bioavailable selective estrogen receptor degrader with an IC50 of 0.2 nM. 了解更多
  18. NPS ALX Compound 4a

    Catalog No. A19703
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    5-HT6 receptor antagonist
    NPS ALX Compound 4a is a potent and selective 5-hydroxytryptamine6 (5-HT6) receptor antagonist with an IC50 of 7.2 nM, which also has a great binding affinity with Ki of 0.2 nM. 了解更多
  19. S 38093

    Catalog No. A19694
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    H3 receptor antagonist
    S 38093 is a brain-penetrant antagonist of H3 receptor, with Ki of 8.8, 1.44 and 1.2 ?M for rat, mouse and human H3 receptors, respectively. 了解更多
  20. Aticaprant

    Catalog No. A19664
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    kappa opioid receptor antagonist
    Aticaprant (CERC-501) is a potent and centrally-penetrant kappa opioid receptor antagonist with a Ki of 0.807 nM. 了解更多
  21. OBE022

    Catalog No. A19626
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    PGF2α receptor antagonist
    OBE022 is an oral and selective prostaglandin F2α (PGF2α) receptor antagonist, with Kis of 1 nM, 26 nM for human and rat FP receptors, respectively. 了解更多
  22. TAK-828F

    Catalog No. A19611
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    RORγt inverse agonist
    TAK-828F is a potent, selective, and orally available retinoic acid receptor-related orphan receptor γt (RORγt) inverse agonist (binding IC50=1.9 nM, reporter gene IC50=6.1 nM). 了解更多
  23. MRE3008F20

    Catalog No. A19604
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    adenosine A3 receptor antagonist
    MRE3008F20 is a highly potent and selective antagonist of adenosine A3 receptor (AA3R), inhibits agonist-induced cAMP elevation in resting T lymphocytes with an IC50 of 5 nM. 了解更多
  24. L-Kynurenine

    Catalog No. A19603
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    aryl hydrocarbon receptor agonist
    L-Kynurenine is a metabolite of the amino acid L-tryptophan. L-Kynurenine is an aryl hydrocarbon receptor agonist. 了解更多
  25. Methiothepin mesylate

    Catalog No. A19599
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    5-HT2 receptor antagonist
    Methiothepin mesylate is a potent and non-selective 5-HT2 receptor antagonist, with pKds of 7.10 (5-HT1A), 7.28 (5HT1B), 7.56 (5HT1C), 6.99 (5HT1D), 7.0 (5-HT5A), 7.8 (5-HT5B), 8.74 (5-HT6), and 8.99 (5-HT7), and pKis of 8.50 (5HT2A), 8.68 (5HT2B), and 8.35 (5HT2C). 了解更多
  26. N6-Cyclopentyladenosine

    Catalog No. A19595
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    Adenosine A1 receptor agonist
    N6-Cyclopentyladenosine (CPA) is a selective Adenosine A1 receptor agonist, with Ki values of 2.3 nM, 790 nM and 43 nM for human A1, A2A and A3 receptors, respectively. 了解更多
  27. ORIC-101

    Catalog No. A19587
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    glucocorticoid receptor antagonist
    ORIC-101 is a highly potent and selective glucocorticoid receptor antagonist, with an EC50 of 5.6 nM. Anti-cancer activity. 了解更多
  28. AGL-2263

    Catalog No. A19525
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    insulin receptor (IR) blocker
    AGL-2263 is an insulin receptor (IR) blocker. 了解更多
  29. Bucindolol

    Catalog No. A19524
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    β1-adrenergic receptor blocker
    Bucindolol is a β1-adrenergic receptor blocker, with intrinsic sympathomimetic activity, used in the research of heart failure. 了解更多
  30. S-8510 phosphate

    Catalog No. A19513
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    BDZ receptor agonist
    S-8510 (phosphate) is an inverse Benzodiazepine (BDZ) receptor agonist, with Kis of 34.6 nM, 36.2 nM for ?CGABA and +GABA respectively. 了解更多
  31. BAY-1316957

    Catalog No. A19495
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    EP4 receptor antagonist
    BAY-1316957 is a highly potent and selective EP4 receptor antagonist with an IC50 of 15.3 nM. Good oral bioavailability. 了解更多
  32. LM22B-10

    Catalog No. A19485
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    TrkB/TrkC neurotrophin receptor activator
    LM22B-10 is an activator of TrkB/TrkC neurotrophin receptor, and can induce TrkB, TrkC, AKT and ERK activation in vitro and in vivo. 了解更多
  33. Apararenone

    Catalog No. A19480
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    mineralocorticoid receptor antagonist
    Apararenone (MT-3995) is a novel non-steroidal mineralocorticoid receptor antagonists under development for the treatment of diabetic nephropathies and non-alcoholic steatohepatitis. 了解更多
  34. Carbacyclin

    Catalog No. A19469
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    PGI2 receptor agonist and vasodilator
    Carbacyclin is a PGI2 analogue, acts as a prostacyclin (PGI2) receptor agonist and vasodilator, and potently inhibits platelet aggregation. 了解更多
  35. Tedatioxetine hydrobromide

    Catalog No. A19418
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    triple reuptake inhibitor/5-HT2A/5-HT2C/5-HT3/α1A-adrenergic receptor antagonis
    Tedatioxetine hydrobromide acts as a triple reuptake inhibitor and 5-HT2A, 5-HT2C, 5-HT3 and α1A-adrenergic receptor antagonist. 了解更多
  36. Vabicaserin hydrochloride

    Catalog No. A19403
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    5-HT2C receptor-selective agonist
    Vabicaserin hydrochloride is a 5-hydroxytryptamine 2C (5-HT2C) receptor-selective agonist with an EC50 of 8 nM. 了解更多
  37. MM 07

    Catalog No. A19388
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    apelin receptor agonist
    MM 07 is a biased apelin receptor agonist, with a KD of 300 nM in CHO-K1 cells and a KD of 172 nM in human heart. 了解更多
  38. Pratosartan

    Catalog No. A19381
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    angiotensin II receptor antagonist
    Pratosartan is a selective angiotensin II receptor antagonist. 了解更多
  39. BT18

    Catalog No. A19378
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    BT18 is a molecule mimic with function similar to glial cell line-derived neurotrophic factor (GDNF). BT18 shows an effect on GDNF family receptor GFRα1 and RET receptor tyrosine kinase RetA function. 了解更多
  40. LAU159

    Catalog No. A19357
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    α1β3 GABA(A) receptor modulator
    LAU159 is a functionally selective positive modulator of α1β3 GABA(A) receptor with an EC50 of 2.2 μM. 了解更多
  41. Loreclezole

    Catalog No. A19295
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    GABAA receptor modulator
    Loreclezole, an antiepileptic compound, is a selective GABAA receptor modulator and acts as a positive allosteric modulator of β2 or β3-subunit containing receptors. 了解更多
  42. Raclopride

    Catalog No. A19204
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    dopamine D2/D3 receptor antagonist
    Raclopride is a dopamine D2/D3 receptor antagonist, which binds to D2 and D3 receptors with dissociation constants (Kis) of 1.8 nM and 3.5 nM, respectively, but has a very low affinity for D1 and D4 receptors with Kis of 18000 nM and 2400 nM, respectively. 了解更多
  43. CYT-1010

    Catalog No. A19176
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    mu-opioid receptor agonist
    CYT-1010 is a mu-opioid receptor agonist extracted from patent WO2013173730A2, with EC50s of 13.1 nM and 0.0053 nM on beta-arrestin recruitment and inhibition of cAMP production, respectively. 了解更多
  44. (R)-Serine

    Catalog No. A17978
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    NMDA glutamate receptor co-agonist
    (R)-Serine, an endogenous amino acid involved in glia-synapse interactions that has unique neurotransmitter characteristics, is a potent co-agonist at the NMDA glutamate receptor. 了解更多
  45. Ulipristal acetate

    Catalog No. A21041
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    progesterone receptor modulator
    Ulipristal (acetate) is a novel selective progesterone receptor modulator (SPRM) for the treatment of benign gynecological conditions such as uterine myoma. 了解更多
  46. N6-Cyclohexyladenosine

    Catalog No. A21008
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    A1 receptor agonist
    N6-Cyclohexyladenosine is a selective A1 receptor agonist (EC50 = 8.2 nM). 了解更多
  47. Eglumegad

    Catalog No. A21005
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    group II (mGlu2/3) receptor agonist
    Eglumegad (LY354740) is a highly potent and selective group II (mGlu2/3) receptor agonist with IC50s of 5 and 24 nM on transfected human mGlu2 and mGlu3 receptors, respectively. 了解更多
  48. AVE 0991

    Catalog No. A20997
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    angiotensin-(1-7) receptor agonist
    AVE 0991 is a nonpeptide and orally active angiotensin-(1-7) receptor agonist with an IC50 of 21 nM. 了解更多
  49. Decloxizine

    Catalog No. A20964
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    histamine 1 receptor antagonist
    Decloxizine(UCB-1402; NSC289116) is a histamine 1 receptor antagonist. 了解更多
  50. 4-Hydroxytamoxifen

    Catalog No. A20955
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    estrogen receptor modulator
    4-Hydroxytamoxifen is a selective estrogen receptor modulator (SERM). 了解更多

产品 351 到 400 共 1712个

每页
页面:
  1. 6
  2. 7
  3. 8
  4. 9
  5. 10

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