“sn 2”的搜索结果

产品 401 到 450 共 17249个

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  1. MYCi361

    Catalog No. A22431
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    MYC inhibitor
    MYCi361 (NUCC-0196361) is a MYC inhibitor with the Kd of 3.2 μM for binding to MYC. MYCi361 (NUCC-0196361) suppresses tumor growth and enhances anti-PD1 immunotherapy. 了解更多
  2. MYCi975

    Catalog No. A22432
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    MYC inhibitor
    MYCi975 (NUCC-0200975) is an orally active MYC inhibitor, which disrupts MYC/MAX interaction, promotes MYC T58 phosphorylation and MYC degradation, and impairs MYC driven gene expression. 了解更多
  3. CC-92480

    Catalog No. A22433
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    antimyeloma agent
    CC-92480 is a cereblon E3 ubiquitin ligase modulating drug (CELMoD). CC-92480 shows high affinity to cereblon, resulting in potent antimyeloma activity. 了解更多
  4. PHY34

    Catalog No. A22434
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    late-stage autophagy inhibitor
    PHY34 is a late-stage autophagy inhibitor with nanomolar potency and significant antitumor efficacy as a single agent against HGSOC in vivo. 了解更多
  5. Alisol B

    Catalog No. A22435
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    therapeutic compound for bone disorders
    Alisol B is a potentially novel therapeutic compound for bone disorders by targeting the differentiation of osteoclasts as well as their functions. 了解更多
  6. Euphorbia Factor L1

    Catalog No. A22436
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    osteoclastogenesis ihibitor
    Euphorbia factor L1, a diterpenoid isolated from Euphorbia lathyris, inhibits osteoclastogenesis and induces osteoclast apoptosis. 了解更多
  7. Flavokawain B

    Catalog No. A22437
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    apoptosis inducer
    Flavokawain B (Flavokavain B) is a chalcone isolated from the root extracts of kava-kava plant and a potent apoptosis inducer for inhibiting the growth of various cancer cell lines. 了解更多
  8. Gardenia yellow

    Catalog No. A22438
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    antidepressant agent
    Gardenia yellow is an active member of crocin, increases mRNA expression of SIRT3, and acts as an orally active antidepressant agent. 了解更多
  9. Pomolic acid

    Catalog No. A22439
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    antitumor agent
    Randialic acid A (Pomolic acid) is a pentacyclic triterpene isolated from Euscaphis japonica (Tunb.). Randialic acid A (Pomolic acid) inhibits tumor cells growth and induces cell apoptosis. Randialic acid A (Pomolic acid) has a potential for the treatment of prostate cancer (PC). 了解更多
  10. Perillyl alcohol

    Catalog No. A22440
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    antitumor agent
    Perillyl alcohol, a monoterpene, is active in inducing apoptosis in tumor cells without affecting normal cells. 了解更多
  11. 4-Hydroxybenzyl alcohol

    Catalog No. A22441
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    Inhibitor of tumor angiogenesis and growth
    4-Hydroxybenzyl alcohol is a phenolic compound widely distributed in various kinds of plants. Anti-inflammatory, anti-oxidant, anti-nociceptive activity. Neuroprotective effect. Inhibitor of tumor angiogenesis and growth. 了解更多
  12. Nerol

    Catalog No. A22442
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    Antifungal agent
    Nerol is a constituent of neroli oil. Nerol Nerol triggers mitochondrial dysfunction and induces apoptosis via elevation of Ca2+ and ROS. Antifungal activity. 了解更多
  13. Astramembrangenin

    Catalog No. A22443
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    telomerase activation agent
    Astramembrangenin (Cycloastragenol) is a compound isolated from the roots of Astragalus kuhitangi (Nevski) Sirj. 了解更多
  14. Glycochenodeoxycholic acid

    Catalog No. A22444
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    detergent
    Glycochenodeoxycholic acid (Chenodeoxycholylglycine) is a bile acid formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. Glycochenodeoxycholic acid (Chenodeoxycholylglycine) induces hepatocyte apoptosis. 了解更多
  15. BTK inhibitor 1 (Compound 27)

    Catalog No. A22445
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    BTK inhibitor
    BTK inhibitor 1 (compound 27) is an inhibitor of BTK with an IC50 of 0.11 nM for Btk and inhibits B cell activation in hWB with an IC50 of 2 nM. 了解更多
  16. 2'-Deoxyuridine 5'-monophosphate disodium salt

    Catalog No. A22446
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    Antibacterial agent
    2'-Deoxyuridine 5'-monophosphate disodium salt (dUMP) is a substrate for thymidylate synthase and is converted to deoxythymidine monophosphate (dTMP). The inhibition of dUMP to dTMP at the methylation step is a key in controlling bacterial and eukaryotic cell growth. 了解更多
  17. Glycochenodeoxycholic acid sodium salt

    Catalog No. A22447
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    detergent
    Glycochenodeoxycholic acid sodium salt (Chenodeoxycholylglycine sodium salt) is a bile acid formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. Glycochenodeoxycholic acid sodium salt (Chenodeoxycholylglycine sodium salt) induces hepatocyte apoptosis. 了解更多
  18. Periplocin

    Catalog No. A22448
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    antitumor agent
    Periplocin is a cardiotonic steroid isolated from Periploca forrestii. Periplocin promotes tumor cell apoptosis and inhibits tumor growth. Periplocin has the potential to facilitate wound healing through the activation of Src/ERK and PI3K/Akt pathways mediated by Na/K-ATPase. 了解更多
  19. Coniferaldehyde

    Catalog No. A22449
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    inducer of heme oxygenase-1
    Coniferaldehyde (Ferulaldehyde), isolated from the ethanol extract of Vitex rotundifolia fruits, is an effective inducer of heme oxygenase-1 (HO-1). 了解更多
  20. Sinensetin

    Catalog No. A22450
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    anti-inflammatory agent
    Sinensetin is a methylated flavone found in certain citrus fruits. pocess potent antiangiogenesis and anti-inflammatory, sinensetin enhances adipogenesis and lipolysis. 了解更多
  21. CPI-1189

    Catalog No. A22451
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    proapoptotic cytokine tumor necrosis factor alpha inhibitor
    CPI-1189 (REN 1654, REN 1189) is the proapoptotic cytokine tumor necrosis factor (TNF) alpha inhibitor. 了解更多
  22. GPNA hydrochloride

    Catalog No. A22452
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    glutamine transporter ASCT2 inhibitor
    GPNA hydrochloride is a well known substrate of the enzyme γ-glutamyltransferase (GGT). GPNA hydrochloride is a specific glutamine (Gln) transporter ASCT2 inhibitor. 了解更多
  23. Quisinostat dihydrochloride

    Catalog No. A22453
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    pan-HDAC inhibitor
    Quisinostat dihydrochloride (JNJ-26481585 dihydrochloride) is an orally available, potent pan-HDAC inhibitor with IC50s of 0.11 nM, 0.33 nM, 0.64 nM, 0.46 nM, and 0.37 nM for HDAC1, HDAC2, HDAC4, HDAC10 and HDAC11, respectively. Quisinostat dihydrochloride has a broad spectrum antitumoral activity. 了解更多
  24. 3-Nitropropanoic acid

    Catalog No. A22454
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    irreversible inhibitor of succinate dehydrogenase
    3-Nitropropanoic acid (β-Nitropropionic acid) is an irreversible inhibitor of succinate dehydrogenase. 3-Nitropropanoic acid exhibits potent antimycobacterial activity with a MIC value of 3.3 μM. 了解更多
  25. Ligustrazine hydrochloride

    Catalog No. A22455
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    antioxidant agent
    Ligustrazine hydrochloride (Tetramethylpyrazine, Tetrapyrazine) is a chemical compound found in natto and in fermented cocoa beans with anti-inflammation, antioxidant, antiplatelet, and antiapoptosis activities. 了解更多
  26. Tetrahydropalmatine hydrochloride

    Catalog No. A22456
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    analgesic agent
    Tetrahydropalmatine hydrochloride (DL-Tetrahydropalmatine hydrochloride), an active component isolated from corydalis, possesses analgesic effects. Tetrahydropalmatine hydrochloride acts through inhibition of amygdaloid release of dopamine to inhibit an epileptic attack in rats. 了解更多
  27. Vanillyl alcohol

    Catalog No. A22457
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    flavoring agent
    Vanillyl alcohol (p-(Hydroxymethyl)guaiacol), derived from vanillin, is a phenolic alcohol and is used as a flavoring agent in foods and beverages. 了解更多
  28. Ursonic acid

    Catalog No. A22458
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    anticancer agent
    Ursolic acid, a naturally occurring triterpenoid, induces the apoptosis of human cancer cells through multiple signaling pathways. 了解更多
  29. Flavone

    Catalog No. A22459
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    antioxidant agent
    Flavone (2-Phenylchromone, 2-Phenyl-4-chromone, 2-Phenyl-4-benzopyron), a class of flavonoids, mainly found in spices and red or purple plant foods with antioxidant, anti-proliferative, anti-tumor, anti-microbial, estrogenic, acetyl cholinesterase, anti-inflammatory activities and are also used in cancer, cardiovascular disease, neurodegenerative disorders etc. 了解更多
  30. Cepharanthine

    Catalog No. A22460
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    anti-inflammatory agent
    Cepharanthine is an alkaloid derived from Stephania cepharantha Hayata, with possesses anti-inflammatory and antioxidative activities. 了解更多
  31. Ganoderic acid A

    Catalog No. A22461
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    AK-STAT3 signaling pathway inhibitor
    Ganoderic acid A can inhibit of the JAK-STAT3 signaling pathway, also inhibit proliferation, viability, ROS. 了解更多
  32. Pyridostatin TFA salt

    Catalog No. A22462
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    Pyridostatin stabilizes G-quadruplexes (G4s) in cells and elicits a DNA damage response by causing the formation of DNA double strand breaks (DSB). 了解更多
  33. CFI-400437 HCl

    Catalog No. A22463
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    CFI-400437 is a potent and selective inhibitor of polo-like kinase 4 (PLK4). 了解更多
  34. FBN33428

    Catalog No. A22464
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    FBN33428, also known as Fmoc-?Phe-?Lys(Boc)?-?PAB; is a Hydrolyzable linker for making ADC conjugate 了解更多
  35. Violanthrone-79

    Catalog No. A22465
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    Violanthrone-79 is an n-channel organic semiconductor 了解更多
  36. Norbergenin

    Catalog No. A22466
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    Norbergenin, also known as Demethylbergenin, is the O-demethyl derivative of bergenin, the main component of Mallotus japonicus.It shows moderate antioxidant activity with IC(50)= 13 μM in DPPH radical scavenging and 32 μM in superoxide anion scavenging. 了解更多
  37. XL092

    Catalog No. A22468
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    XL092 is an ATP-competitive inhibitor of multiple RTKs including MET, VEGFR2, AXL and MER, with IC50 values in cell-based assays of 15, 1.6, 3.4, and 7.2 nM respectively. 了解更多
  38. (R)-Ofloxacin

    Catalog No. A22469
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    (R)-Ofloxacin is a R-isomer of Ofloxacin.Ofloxacin is an antibiotic useful for the treatment of a number of bacterial infections. 了解更多
  39. SM-102

    Catalog No. A22470
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    SM-102 is an ionizable amino lipid that has been used in combination with other lipids in the formation of lipid nanoparticles. 了解更多
  40. Topovale

    Catalog No. A22471
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    Topovale, also known as ARC-111, is a potent topoisomerase I inhibitor. 了解更多
  41. WM 3835

    Catalog No. A22472
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    WM 3835 is a lysine acetyltransferase HBO1 (KAT7) inhibitor. 了解更多
  42. Etalocib

    Catalog No. A22473
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    Etalocib, also known as LY293111 and VML295, is a potent and selective inhibitor of the lipoxygenase pathway either directly through 5'-lipoxygenase or via antagonism of the leukotriene B4 (LTB4) receptor. 了解更多
  43. Pibrentasvir

    Catalog No. A22474
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    Pibrentasvir, also known as ABT-530, is a protease inhibitor potentially for the treatment of HCV infection. 了解更多
  44. XL177A

    Catalog No. A22475
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    USP7 inhibitor
    XL177A is a potent USP7 inhibitor that irreversibly inhibits USP7 with sub-nM potency and selectivity across the human proteome. 了解更多
  45. Sisunatovir HCl

    Catalog No. A22476
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    Sisunatovir, also known as RV521, is a highly potent fusion inhibitor with efficacy against a panel of clinical isolates of RSV-A and RSV-B viruses. 了解更多
  46. Nifeviroc

    Catalog No. A22478
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    CCR5 antagonist
    Nifeviroc is a CCR5 antagonist potentially for treatment of inflammatory responses to HIV type-1 infection 了解更多
  47. Plitidepsin

    Catalog No. A22480
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    Plitidepsin is a cyclic depsipeptide isolated from the marine tunicate Aplidium albicans. Plitidepsin displays a broad spectrum of antitumor activities, inducing apoptosis by triggering mitochondrial cytochrome c release, initiating the Fas/DC95, JNK pathway and activating caspase 3 activation. This agent also inhibits elongation factor 1-a, thereby interfering with protein synthesis, and induces G1 arrest and G2 blockade, thereby inhibiting tumor cell growth. 了解更多
  48. (S,R,S)-AHPC free base

    Catalog No. A22481
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    (S,R,S)-AHPC , also known as also known as MDK7526; VHL Ligand 1; Protein degrader 1, is a potent and selective protein degrader. MDK7526 is potential useful for the targeted degradation of the androgen receptor. 了解更多
  49. AH10639 phosphate

    Catalog No. A22482
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    AH10639 is a novel inhibitor of Pneumocystis carinii and Toxoplasma gondii dihydrofolate reductase. 了解更多
  50. Merafloxacin

    Catalog No. A22483
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    Merafloxacin, also known as CI 934, is a fluoroquinolone antibacterial, which was also identified as a ?1 PRF inhibitor of SARS-CoV-2. Frameshift inhibition by merafloxacin is robust to mutations within the pseudoknot region and is similarly effective on ?1 PRF of other beta coronaviruses. Importantly, frameshift inhibition by merafloxacin substantially impedes SARS-CoV-2 replication in Vero E6 cells, thereby providing the proof of principle of targeting ?1 PRF as an effective antiviral strategy for SARS-CoV-2. 了解更多

产品 401 到 450 共 17249个

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  3. 9
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