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CCMI is a potent and selective α7 nAChR-positive allosteric modulator, does not bind to or activate α7 nAChRs via the orthosteric site, and causes significant positive modulation of agonist-induced currents at α7 nAChRs.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.76 mL | 128.78 mL | 257.57 mL |
| 0.5 mM | 5.15 mL | 25.76 mL | 51.51 mL |
| 1 mM | 2.58 mL | 12.88 mL | 25.76 mL |
| 5 mM | 0.52 mL | 2.58 mL | 5.15 mL |
*The above data is based on the productmolecular weight 388.25. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A21534 |
|---|---|
| 作用机制 | Modulator (调节剂) |
| M. Wt | 388.25 |
| Formula | C19H15Cl2N3O2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 917837-54-8 |
| Synonyms | IACS10759, IACS 10759 |
| SMILES | O=C(NC1=CC=C(Cl)C=C1)/C(C2=CC(C)=NO2)=C/NC3=CC=C(Cl)C=C3 |
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