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29 个项目
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BX471 hydrochloride
Catalog No. A21886 non-peptide CCR1 antagonistBX471 hydrochloride (ZK-811752 hydrochloride) is a potent, selective non-peptide CCR1 antagonist with Ki of 1 nM for human CCR1, and exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4. 了解更多 -
RS102895 hydrochloride
Catalog No. A20918 CCR2 antagonistRS102895 hydrochloride is a potent CCR2 antagonist, with an IC50 of 360 nM, and shows no effect on CCR1. 了解更多 -
PF-4136309
Catalog No. A15127 CCR2 antagonistPF-4136309 is a potent, selective, and orally bioavailable CCR2 antagonist, with IC50s of 5.2 nM, 17 nM and 13 nM for human, mouse and rat CCR2. 了解更多 -
GSK2239633A
Catalog No. A12175 CCR4 antagonistGSK2239633A is a CC-chemokine receptor 4 (CCR4) antagonist, which inhibits the binding of [125I]-TARC to human CCR4 with a pIC50 of 7.96????0.11. 了解更多 -
Teijin compound 1
Catalog No. A13380 CCR 2 antagonistTeijin compound 1 is a specific CCR 2 antagonist with IC50s of 24 and 180 nM in chemotaxis and binding assay, respectively. 了解更多 -
CCR4 antagonist 2
Catalog No. A18471 CCR4 拮抗剂CCR4 antagonist 2 (Compound 31) is a novel potent, orally bioavailable small molecule antagonists of CC chemokine receptor 4 (CCR4) that inhibits Treg trafficking into the Tumor Microenvironment without suppressing the number of Treg in healthy tissues. 了解更多 -
PF-04634817
Catalog No. A18659 CCR2 /CCR5 dual 拮抗剂PF-04634817 is an orally administered CCR2 and CCR5 chemokine receptor antagonist, for the treatment of diabetic nephropathies and diabetic macular oedema. 了解更多 -
BI-639667
Catalog No. A18747 -
Cenicriviroc Mesylate
Catalog No. A17028 CCR2/5 receptors 抑制剂Cenicriviroc(TAK-652,TBR-652)是CCR2和CCR5受体的抑制剂，可使其充当防止病毒进入人细胞的进入抑制剂 了解更多 -
BMS-813160
Catalog No. A17040 -
ZK-756326 dihydrochloride
Catalog No. A16363 CCR8 激动剂ZK-756326是有效的，选择性的非肽CCR8趋化因子受体激动剂。ZK 756326抑制了CCR8配体I-309（CCL1）的结合，IC（50）值为1.8μM。 了解更多 -
Vicriviroc maleate
Catalog No. A15276 -
Cenicriviroc
Catalog No. A13643 CCR2/CCR5 抑制剂Cenicriviroc是用于治疗HIV感染的实验性候选药物.Cenicriviroc是CCR2和CCR5受体的抑制剂，可使其充当阻止病毒进入人体细胞的进入抑制剂。 了解更多 -
TAK-779
Catalog No. A13846 -
INCB 3284 dimesylate
Catalog No. A11104 HCCR2 拮抗剂INCB 3284 dimesylate是一种有效的选择性hCCR2拮抗剂，对单核细胞趋化因子分子与hCCR2的结合和趋化活性表现出强烈的拮抗作用。 了解更多 -
INCB8761 (PF-4136309)
Catalog No. A11136 -
Vicriviroc Malate
Catalog No. A10971 CCR5 拮抗剂Vicriviroc Malate是CCR5拮抗剂，也是HIV-1进入靶细胞的有效抑制剂，对HIV分离株的平均IC50 = 0.46 nM，IC50 = 1?10 nM（n = 52）。 了解更多 -
Maraviroc (UK-427857)
Catalog No. A10556 CCR 拮抗剂Maraviroc (UK-427857)是CCR5受体拮抗剂类别的抗逆转录病毒药物，用于治疗HIV感染。 了解更多
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