微信关注
Total item
Cart Subtotal
￥ 0.00 产品详情
CCT128930是一种具有ATP竞争性的AKT抑制剂，是一种有效的高级吡咯并嘧啶铅化合物，相对于PKA表现出对AKT的选择性，可通过靶向单个氨基酸差异实现。
靶点信息
| Akt2 (Cell-free assay) | p70 S6K (Cell-free assay) | PKA (Cell-free assay) | ||
| 6 nM | 120 nM | 168 nM |
| In vitro (25°C) | DMSO | 59 mg/mL (172.59 mM) | |
| Water | Insoluble | ||
| Ethanol | 5 mg/mL (14.63 mM) | ||
| In vivo | 2% DMSO+30% PEG 300+2% Tween 80+ddH2O | 3 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 29.26 mL | 146.28 mL | 292.57 mL |
| 0.5 mM | 5.85 mL | 29.26 mL | 58.51 mL |
| 1 mM | 2.93 mL | 14.63 mL | 29.26 mL |
| 5 mM | 0.59 mL | 2.93 mL | 5.85 mL |
*The above data is based on the productmolecular weight 341.8 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A11031 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 341.8 |
| Formula | C18H20ClN5 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 885499-61-6 |
| Synonyms | CCT-128930 |
| SMILES | C1CN(CCC1(CC2=CC=C(C=C2)Cl)N)C3=NC=NC4=C3C=CN4 |
产品标签
Product Questions
Product Questions
No Questions
您还可能对下列产品感兴趣
Akt1 and Akt2-IN-1
Akt1 and Akt2-IN-1是Akt1（IC50 = 3.5 nM）和Akt2（IC50 = 42 nM）的变构抑制剂，具有有效且平衡的活性。
Perifosine (NSC-639966)
Perifosine (也为KRX-0401) 充当Akt抑制剂和PI3K抑制剂。
Triciribine
Triciribine，也称为API-2，可抑制Akt的磷酸化水平和激酶活性。
Triciribine phosphate (NSC-280594)
Triciribine phosphate是一种DNA synthesis抑制剂，也抑制PC3细胞系中的Akt和CEM-SS，H9，H9IIIB，U1细胞中的HIV-1，IC50分…
Keywords:购买 CCT128930 | CCT128930 供应商 | 订购 CCT128930 | CCT128930 价格 | CCT128930 生产商 | 订单 CCT128930 | CCT128930 代理商 | 购买 885499-61-6| 885499-61-6 供应商 | 订购 885499-61-6 | 885499-61-6 价格 | 885499-61-6 生产商 | 订单 885499-61-6 | 885499-61-6 代理商|buy CCT128930 | CCT128930 Supplier | purchase CCT128930 | CCT128930 cost | CCT128930 manufacturer | order CCT128930 | CCT128930 distributor | buy 885499-61-6| 885499-61-6 Supplier | purchase 885499-61-6 | 885499-61-6 cost | 885499-61-6 manufacturer | order 885499-61-6 | 885499-61-6 distributor