微信关注
Total item
Cart Subtotal
￥ 0.00 Cell Metabolism
-
HSP27 inhibitor J2
Catalog No. A18874 HSP27 inhibitorHSP27 inhibitor J2 (J2) is a HSP27 inhibitor, which significantly induces abnormal HSP27 dimer formation and inhibits a production of HSP27 giant polymers, thereby having an effect of inhibiting a chaperone function of the HSP27 and reducing a cell protection function thereof. 了解更多 -
Retaspimycin
Catalog No. A15221 Hsp90 inhibitorRetaspimycin is a potent and water-soluble inhibitor of Hsp90, with EC50s of 119 nM for both Hsp90 and Grp9. 了解更多 -
Apoptozole
Catalog No. A21177 Hsc70 and Hsp70 inhibitorApoptozole (Apoptosis Activator VII) is an inhibitor of the ATPase domain of Hsc70 and Hsp70, with Kds of 0.21 and 0.14?μM, respectively, and can induce apoptosis. 了解更多 -
SNX-5422 Mesylate
Catalog No. A21512 Hsp90 inhibitorSNX-5422 Mesylate (PF-04929113 Mesylate), a prodrug of SNX-2112, is an orally active Hsp90 inhibitor, with a Kd of 41 nM, and also induces Her-2 degradation, with an IC50 of 37?nM. 了解更多 -
HSP70-IN-1
Catalog No. A21716 HSP inhibitorHSP70-IN-1 is a heat shock protein (HSP) inhibitor; inhibits the growth of Kasumi-1 cells with an IC50 of 2.3 μM. 了解更多 -
17-AAG (KOS953)
Catalog No. A10010 HSP90 抑制剂17-AAG (KOS953)是一种有效的HSP90抑制剂，无细胞试验中IC50为5 nM，作用于来自肿瘤细胞的HSP90比作用于来自正常细胞HSP90结合亲和力高100倍。 了解更多 -
AUY922 (Luminespib, NVP-AUY922)
Catalog No. A10659 HSP90 抑制剂AUY922 (Luminespib,NVP-AUY922)是一种高效的HSP90抑制剂，在Hsp90 FP结合测定中的IC50 = 21 nM，并在体外抑制多种人类癌细胞系的增殖，GI50平均为9 nM。Luminespib (AUY-922, NVP-AUY922)是一种高效的HSP90抑制剂，无细胞试验中作用于HSP90α/β的IC50为13 nM /21 nM，对HSP90家族成员GRP94和TRAP-1具有稍弱的作用，与任何小分子HSP90配体均可紧密结合。 了解更多 -
NVP-BEP800
Catalog No. A10660 HSP90 抑制剂NVP-BEP800是一种新型的，完全合成的，口服可生物利用的抑制剂，可与Hsp90的NH2末端ATP结合袋结合。 了解更多 -
Onalespib (AT13387)
Catalog No. A11062 HSP90 抑制剂Onalespib (AT13387)是Hsp90的靶向抑制剂，可抑制其伴侣功能并促进涉及肿瘤细胞增殖和存活的致癌信号蛋白的降解。 了解更多 -
PF-04929113 (SNX-5422)
Catalog No. A11074 Hsp90 抑制剂PF-04929113 (SNX-5422)是一种有效的，选择性的HSP90抑制剂，Kd为41 nM，且诱导Her-2降解，IC50为37 nM。 了解更多 -
Ganetespib (STA-9090)
Catalog No. A11402 Hsp90 抑制剂Ganetespib (STA-9090)是Hsp90的有效合成小分子抑制剂，Hsp90是一种伴侣蛋白，对于某些其他蛋白的功能至关重要，这些蛋白可驱动许多不同类型的癌症的生长，增殖和存活。 了解更多 -
17-DMAG HCl (Alvespimycin)
Catalog No. A10011 Hsp90 抑制剂17-DMAG HCl (Alvespimycin)是17-AAG和格尔德霉素的水溶性类似物，与Hsp90的ATP结合位点结合并抑制其伴侣活性。显示出比17-AAG更有效的抗肿瘤活性。 了解更多 -
KW-2478
Catalog No. A11195 -
PU-H71
Catalog No. A11130 -
IPI-504 (Retaspimycin HCl)
Catalog No. A11269 -
CUDC-305 (DEBIO-0932 )
Catalog No. A12648 HSP90 抑制剂CUDC-305 (DEBIO-0932) 是一种新型的热休克蛋白90（HSP90）抑制剂，对HSP90 alpha/beta具有很强的亲和力，对HSP90α和HSP90β的IC50值分别为100和103nM。具有很高的口服生物利用度，并且对多种癌细胞系均具有强大的抗增殖活性（平均IC50为220 nmol/L）。包括许多对护理标准（SOC）药物有抵抗力的非小细胞肺癌（NSCLC）细胞系。 了解更多 -
PU-WS13
Catalog No. A14129 -
Macbecin I
Catalog No. A16050 -
Rocaglamide
Catalog No. A12765 Heat shock reporterRocaglamide是 T 细胞中一种有效的 NF-κB 活化抑制剂。Rocaglamide 是一种有效的选择性热休克因子 1 (HSF1) 活化抑制剂，IC50 约为 50 nM。Rocaglamide 还抑制翻译起始因子 eIF4A 的功能。Rocaglamide 还具有抗癌特性。 了解更多 -
Gedunin
Catalog No. A16034 -
Nepicastat HCl
Catalog No. A11172 -
Tetrahydropapaverine HCl
Catalog No. A10920 Hydroxylase 抑制剂Tetrahydropapaverine HCl是TIQs的一种，是Salsolinol和Tetrahydropapaveroline的类似物，对多巴胺神经元具有神经毒性作用。 了解更多 -
LX 1606 Hippurate
Catalog No. A10542 Hydroxylase 抑制剂LX 1606 hippurate是一种口服生物可利用的小分子色氨酸羟化酶(TPH)抑制剂，具有潜在的抗旋转能活性。 了解更多 -
Nepicastat (free base) (SYN-117)
Catalog No. A10637 dopamine beta-hydroxylase 抑制剂Nepicastat (free base) (SYN-117)是多巴胺β-羟化酶的抑制剂，该酶催化多巴胺向去甲肾上腺素的转化。 了解更多 -
LX 1606 (Telotristat)
Catalog No. A11785 Serotonin synthesis 抑制剂LX 1606 (Telotristat)是一种口服生物可利用的小分子色氨酸羟化酶（TPH）抑制剂，具有潜在的抗血清素活性。 了解更多 -
Ro 61-8048
Catalog No. A12833 Hydroxylase 抑制剂Ro 61-8048是有效的竞争性犬尿氨酸3-羟化酶抑制剂（Ki = 4.8 nM，IC50 = 37 nM）。 了解更多
FILTER BY:
Filtering:
- 作用机制: Inhibitor (抑制剂) 删除该内容
购物选项
- 分类
-
- Cytochrome P450 (29)
- PPAR (1)
- PDE (71)
- HSP (42)
- Hydroxylases (12)
- Factor Xa (16)
- MAO (30)
- DHFR (6)
- Dehydrogenases (19)
- Procollagen C-proteinase (1)
- Carbonic Anhydrase (12)
- FAAH (11)
- 15-PGDH (2)
- CETP (6)
- Ferroptosis (5)
- HMG-CoA Reductase (15)
- Isocitrate Dehydrogenase (IDH) (14)
- IDO (13)
- Lipase (9)
- Phospholipases (10)
- Lipoxygenase (11)
- NAMPT (5)
- GLUT (3)
- Antimetabolite (3)
- Lipid Metabolism (1)
- SREBP (2)
- LDL (1)
- Foxo1 (1)
- DGAT (6)
- Farnesyl Transferase (6)
- CRM1 (6)
- Thioredoxin (2)
- Decarboxylase (1)
- ACLY (2)
- Fatty acid synthase (FASN) (6)
- Lactate dehydrogenase A (LDHA) (1)
- PFKFB3 (3)
- Ribonucleotide Reductase (2)
- Acetyl-CoA Carboxylase (6)
- Glucosidase (3)
- Phosphatase (4)
- 靶点
-
- 5-lipoxygenase (1)
- Carbonic Anhydrase (6)
- Carbonic Anhydrase I (3)
- Carbonic Anhydrase II (3)
- Carbonic Anhydrase IV (2)
- Carbonic Anhydrase IX (2)
- CETP (4)
- COX (1)
- COX-1 (1)
- COX-2 (2)
- DNMT (1)
- FTase (4)
- HDAC1 (1)
- HMG-CoA Reductase (9)
- HSP90 (1)
- KDM1A (LSD1) (1)
- MAO-A (1)
- MAO-B (1)
- PDE4 (1)
- PDE5 (1)
- Src (1)
- TNF-α (1)
ADOOQ 产品质量保证
We promise all products to perform as described.