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Cell Metabolism

产品 551 到 600 共 623个

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  1. (24S)-MC 976
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    (24S)-MC 976

    Catalog No. A14962
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    (24S)-MC 976是维生素D3衍生物。 了解更多
  2. 1alpha, 24, 25-Trihydroxy VD2
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    1alpha, 24, 25-Trihydroxy VD2

    Catalog No. A14968
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    1alpha, 24, 25-Trihydroxy VD2是维生素D类似物。 了解更多
  3. 1alpha, 25-Dihydroxy VD2-D6
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    1alpha, 25-Dihydroxy VD2-D6

    Catalog No. A14969
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    1alpha, 25-Dihydroxy VD2-D6是氘化的维生素D形式。 了解更多
  4. 1alpha-Hydroxy VD4
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    1alpha-Hydroxy VD4

    Catalog No. A14970
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    1alpha-Hydroxy VD4可有效诱导单核细胞白血病U937，P39/TSU和P31/FUJ细胞分化。 了解更多
  5. 24, 25-Dihydroxy VD2
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    24, 25-Dihydroxy VD2

    Catalog No. A14972
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    24, 25-Dihydroxy VD2是维生素D2的羟基代谢物；维生素D的合成类似物。 了解更多
  6. 24, 25-Dihydroxy VD3
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    24, 25-Dihydroxy VD3

    Catalog No. A14973
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    24, 25-Dihydroxy VD3是与维生素D3的活性形式1，25-二羟基维生素D3密切相关的化合物，但是与维生素D3本身和25-羟基维生素D3一样，其在体内和体外都没有作为激素的活性。 了解更多
  7. 25-Hydroxy VD2-D6
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    25-Hydroxy VD2-D6

    Catalog No. A14974
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    25-Hydroxy VD2-D6是维生素D2的标记代谢产物。 了解更多
  8. 3-O-(2-Aminoethyl)-25-hydroxyvitamin D3
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    3-O-(2-Aminoethyl)-25-hydroxyvitamin D3

    Catalog No. A14977
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    3-O-(2-Aminoethyl)-25-hydroxyvitamin D3是一种维生素D3衍生物。 了解更多
  9. Calcifediol monohydrate
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    Calcifediol monohydrate

    Catalog No. A15032
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    Calcifediol monohydrate (25-hydroxy Vitamin D3)是由胆钙化固醇25-羟化酶将维生素D3（胆钙化固醇）羟化而在肝脏中产生的前激素。 了解更多
  10. Impurity B of Calcitriol
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    Impurity B of Calcitriol

    Catalog No. A15123
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    Impurity B of Calcitriol是维生素D的激素活性形式，骨化三醇是激活维生素D受体（VDR）的维生素D3的活性代谢产物。 了解更多
  11. Impurity C of Alfacalcidol
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    Impurity C of Alfacalcidol

    Catalog No. A15124
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    Impurity C of Alfacalcidol是一种非选择性VDR活化剂药物。 了解更多
  12. Impurity C of Calcitriol
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    Impurity C of Calcitriol

    Catalog No. A15125
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    Impurity C of Calcitriol是维生素D的激素活性形式，骨化三醇是激活维生素D受体（VDR）的维生素D3的活性代谢产物。 了解更多
  13. Impurity of Calcipotriol
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    Impurity of Calcipotriol

    Catalog No. A15126
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    Impurity of Calcipotriol是维生素D的激素活性形式，骨化三醇是维生素D3的活性代谢产物，可激活维生素D受体（VDR）。 了解更多
  14. Maxacalcitol
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    Maxacalcitol

    Catalog No. A15153
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    Maxacalcitol是非钙化的维生素D3类似物，是VDR样受体的配体。 了解更多
  15. Secalciferol
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    Secalciferol

    Catalog No. A15237
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    Vitamin D metabolit
    Secalciferol是维生素D的代谢产物，维生素D是可能的抗炎类固醇，与骨骼骨化有关。 了解更多
  16. Tacalcitol
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    Tacalcitol

    Catalog No. A15251
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    Tacalcitol通过调节钙促进正常的骨骼发育。 了解更多
  17. Tacalcitol monohydrate
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    Tacalcitol monohydrate

    Catalog No. A15252
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    Tacalcitol monohydrate通过调节钙促进正常的骨骼发育。 了解更多
  18. VD2-D3
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    VD2-D3

    Catalog No. A15274
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    VD2-D3是维生素D的氘代形式。 了解更多
  19. Vitamin D4
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    Vitamin D4

    Catalog No. A15278
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    Vitamin D4是维生素D的活性类似物。 了解更多
  20. Paricalcitol
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    Paricalcitol

    Catalog No. A11533
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    Paricalcitol是一种用于预防和治疗与慢性肾衰竭相关的继发性甲状旁腺功能亢进(甲状旁腺激素分泌过多)的药物。 了解更多
  21. Calcium D-Panthotenate
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    Calcium D-Panthotenate

    Catalog No. A15905
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    Calcium D-Panthotenate是一种水溶性维生素，对许多动物来说都是必不可少的营养素。 了解更多
  22. Folic acid
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    Folic acid

    Catalog No. A12227
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    Folic acid是B族维生素；对新细胞的产生和维持，DNA合成和RNA合成都是必要的。 了解更多
  23. Pyridoxamine 2HCl
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    Pyridoxamine 2HCl

    Catalog No. A16199
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    Pyridoxamine 2HCl是维生素B6的一种形式。化学上，它基于吡啶环结构，具有羟基，甲基，氨甲基和羟甲基取代基。 了解更多
  24. MC-976
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    MC-976

    Catalog No. A12489
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    Vitamin D3 derivative
    MC-976是维生素D3衍生物。 了解更多
  25. Amprolium HCl
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    Amprolium HCl

    Catalog No. A16410
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    Thiamin 拮抗剂
    Amprolium HCl是硫胺素拮抗剂，可通过阻止硫胺素吸收来阻止碳水化合物的合成。 了解更多
  26. Benserazide HCl (Serazide)
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    Benserazide HCl (Serazide)

    Catalog No. A10125
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    Benserazide hydrochloride (Serazide)是L-芳族氨基酸脱羧酶的抑制剂。 了解更多
  27. Carbidopa
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    Carbidopa

    Catalog No. A10181
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    aromatic-L-amino-acid decarboxylase 抑制剂
    Carbidopa是一种芳香族-L-氨基酸脱羧酶抑制剂，这是一种在L-色氨酸生物合成5-羟色胺和L-DOPA生物合成多巴胺（DA）中重要的酶。 了解更多
  28. Eflornithine hydrochloride hydrate
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    Eflornithine hydrochloride hydrate

    Catalog No. A16174
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    Eflornithine hydrochloride是一种可有效治疗面部多毛症的药物。 了解更多
  29. BMS303141
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    BMS303141

    Catalog No. A13807
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    ATP-citrate lyase 抑制剂
    BMS303141是有效的ATP柠檬酸裂解酶（ACL）抑制剂。BMS303141以8μM的IC50抑制HepG2细胞中的脂质合成，并在鼠类高脂血症模型中降低血浆甘油三酸酯。 了解更多
  30. ETC-1002
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    ETC-1002

    Catalog No. A15815
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    ACL 抑制剂 and AMPK 激活剂
    ETC-1002是一种新颖的，一流的可以降低LDL-C的小分子；肝AMP激活的蛋白激酶（AMPK）的激活剂;对肝ATP-柠檬酸裂解酶也具有有效的抑制活性（IC50 = 29 uM）。 了解更多
  31. TVB-3166
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    TVB-3166

    Catalog No. A18763
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    FASN inhibitor
    TVB-3166 is an orally-available, reversible, potent, and selective FASN inhibitor, inducing apoptosis, inhibiting anchorage-independent cell growth under lipid-rich conditions, and inhibiting in-vivo xenograft tumor growth. 了解更多
  32. TVB-3664
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    TVB-3664

    Catalog No. A18829
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    FASN inhibitor
    TVB-3664 is an orally available, reversible, potent, selective and highly bioavailable fatty acid synthase (FASN) inhibitor, with IC50 values of 18 nM and 12 nM for human and mouse cell palmitate synthesis, respectively. TVB-3664 significantly reduces tubulin palmitoylation and mRNA expression. 了解更多
  33. FASN-IN-2
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    FASN-IN-2

    Catalog No. A13063
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    FASN inhibitor
    FASN-IN-2 is a Fatty Acid Synthase (FASN) inhibitor extracted from patent WO2012122391A1, compound 152, has an IC50 of 0.052 μM and an EC50 of 0.072 μM. 了解更多
  34. HS80
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    HS80

    Catalog No. A21615
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    FASN inhibitor
    HS-80 is an enantiomer of Fasnall, which is a selective fatty acid synthase (FASN) inhibitor. HS-80 is able to inhibit the incorporation of tritiated acetate into lipids with an IC50 of 7.13 μM. 了解更多
  35. Orlistat
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    Orlistat

    Catalog No. A10676
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    Orlistat是一种一般的脂肪酶抑制剂，对人十二指肠液的PL的IC50为122 ng / ml。 了解更多
  36. C75
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    C75

    Catalog No. A14107
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    FASN 抑制剂
    C75是新型有效的脂肪酸合酶抑制剂（FAS），可作为研究代谢紊乱和癌症中脂肪酸合成的工具。 了解更多
  37. C-75 Trans
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    C-75 Trans

    Catalog No. A15331
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    FASN 抑制剂
    C 75是脂肪酸合酶（FAS）的抑制剂，可减少小鼠的食物摄入量和体重。 了解更多
  38. GKA50
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    GKA50

    Catalog No. A12859
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    glucokinase activator
    GKA50是强力的葡萄糖激酶激活剂。 了解更多
  39. Piragliatin
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    Piragliatin

    Catalog No. A13528
    Glucokinase activator
    Piragliatin是一种新型的葡萄糖激酶激活剂，在2型糖尿病患者的吸收后状态和葡萄糖激发后均降低血浆葡萄糖。 了解更多
  40. AM-2394
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    AM-2394

    Catalog No. A16331
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    glucokinase activator
    AM-2394是结构独特的葡萄糖激酶激活剂(GKA)。AM-2394以60 nM的EC50激活葡萄糖激酶(GK)。 了解更多
  41. AZ-33
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    AZ-33

    Catalog No. A13341
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    LDHA 抑制剂
    AZ33是LDHA抑制剂。 了解更多
  42. Atovaquone
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    Atovaquone

    Catalog No. A13708
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    Atovaquone是一种抗原生动物线粒体电子传递抑制剂。 了解更多
  43. Imeglimin
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    Imeglimin

    Catalog No. A16282
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    oxidative phosphorylation blocker
    Imeglimin是一种氧化磷酸化阻滞剂，可抑制肝糖异生，增加肌肉葡萄糖摄取并恢复正常的胰岛素分泌。 了解更多
  44. Imeglimin hydrochloride
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    Imeglimin hydrochloride

    Catalog No. A16283
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    oxidative phosphorylation blocker
    Imeglimin hydrochloride是新型含四氢三嗪的口服降糖药中的第一个，即glimins。已证明它可作用于肝脏，肌肉和胰腺γ-细胞，以独特地靶向2型糖尿病的关键缺陷。 了解更多
  45. PFK15
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    PFK15

    Catalog No. A14287
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    PFKFB3 抑制剂
    PFK15是一种有效的选择性6-磷酸果糖-2-激酶（PFKFB3），IC50为20 nM。 了解更多
  46. PFK-158
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    PFK-158

    Catalog No. A14398
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    PFK-2/FBPase 抑制剂
    PFK-158是6-磷酸果糖-2-激酶/果糖-2,6-双磷酸酶（PFK-2/FBPase）同工型3（PFKFB3）的抑制剂，是3-(3-吡啶基)-1-[4-吡啶基]-2-丙烯-1-酮(3PO)，具有潜在的抗肿瘤活性。 了解更多
  47. 3PO
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    3PO

    Catalog No. A15932
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    PFKFB3 抑制剂
    3PO是PFKFB3（6-磷酸果糖-2-激酶/果糖-2,6-双磷酸酶）抑制剂。 了解更多
  48. Triapine
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    Triapine

    Catalog No. A14306
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    Ribonucleotide reductase 抑制剂
    Triapine是一种有效的核糖核苷酸还原酶抑制剂，具有抑制DNA合成的广谱抗肿瘤活性。 了解更多
  49. Didox
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    Didox

    Catalog No. A16304
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    ribonucleotide reductase 抑制剂
    Didox是核糖核苷酸还原酶（RR）的强抑制剂，可通过阻止脱氧核糖核苷酸的产生来干扰DNA的合成和修复，并且数十年来已显示出抗肿瘤作用。 了解更多
  50. ND-646
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    ND-646

    Catalog No. A20079
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    ACC inhibitor
    ND-646 is an orally bioavailable and steric inhibitor of acetyl-CoA carboxylase (ACC) with IC50s of 3.5 nM and 4.1 nM for recombinant hACC1 and hACC2, respectively. 了解更多

产品 551 到 600 共 623个

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分类
  1. Cytochrome P450 (59)
  2. PPAR (47)
  3. PDE (74)
  4. HSP (47)
  5. Hydroxylases (14)
  6. Factor Xa (17)
  7. MAO (30)
  8. DHFR (10)
  9. Dehydrogenases (27)
  10. Procollagen C-proteinase (1)
  11. Carbonic Anhydrase (12)
  12. LXR (13)
  13. FAAH (11)
  14. 15-PGDH (2)
  15. CETP (6)
  16. Ferroptosis (5)
  17. HMG-CoA Reductase (15)
  18. FXR (14)
  19. Isocitrate Dehydrogenase (IDH) (14)
  20. IDO (13)
  21. Retinoid Receptor (22)
  22. Lipase (12)
  23. Phospholipases (13)
  24. Lipoxygenase (13)
  25. AhR (6)
  26. NAMPT (9)
  27. GLUT (4)
  28. Antimetabolite (10)
  29. Lipid Metabolism (1)
  30. Neuronal Metabolism (1)
  31. SREBP (2)
  32. LDL (3)
  33. Foxo1 (2)
  34. DGAT (6)
  35. Farnesyl Transferase (6)
  36. CRM1 (7)
  37. Thioredoxin (2)
  38. Vitamin (31)
  39. Decarboxylase (3)
  40. ACLY (2)
  41. Fatty acid synthase (FASN) (7)
  42. Glucokinase (3)
  43. Lactate dehydrogenase A (LDHA) (1)
  44. Oxidative Phosphorylation (3)
  45. PFKFB3 (3)
  46. Ribonucleotide Reductase (2)
  47. Acetyl-CoA Carboxylase (6)
  48. Glucosidase (12)
  49. Phosphatase (6)
作用机制
  1. Inhibitor (抑制剂) (394)
  2. Agonist (激动剂) (66)
  3. Antagonist (拮抗剂) (22)
  4. Activator (激活剂) (11)
  5. Modulator (调节剂) (2)
  6. Blocker (阻断剂) (2)
  7. Inducer (诱导剂) (5)
  8. Substrate (底物) (4)
靶点
  1. 5-lipoxygenase (1)
  2. Carbonic Anhydrase (6)
  3. Carbonic Anhydrase I (3)
  4. Carbonic Anhydrase II (3)
  5. Carbonic Anhydrase IV (2)
  6. Carbonic Anhydrase IX (2)
  7. CETP (4)
  8. COX (1)
  9. COX-1 (1)
  10. COX-2 (2)
  11. DNMT (1)
  12. FTase (4)
  13. HDAC1 (1)
  14. HMG-CoA Reductase (9)
  15. HSP90 (1)
  16. KDM1A (LSD1) (1)
  17. MAO-A (1)
  18. MAO-B (1)
  19. PDE4 (1)
  20. PDE5 (1)
  21. Src (1)
  22. TNF-α (1)
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