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￥ 0.00 Cell Metabolism
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PU-H71
Catalog No. A11130 -
IPI-504 (Retaspimycin HCl)
Catalog No. A11269 -
CUDC-305 (DEBIO-0932 )
Catalog No. A12648 HSP90 抑制剂CUDC-305 (DEBIO-0932) 是一种新型的热休克蛋白90（HSP90）抑制剂，对HSP90 alpha/beta具有很强的亲和力，对HSP90α和HSP90β的IC50值分别为100和103nM。具有很高的口服生物利用度，并且对多种癌细胞系均具有强大的抗增殖活性（平均IC50为220 nmol/L）。包括许多对护理标准（SOC）药物有抵抗力的非小细胞肺癌（NSCLC）细胞系。 了解更多 -
PU-WS13
Catalog No. A14129 -
Macbecin I
Catalog No. A16050 -
Rocaglamide
Catalog No. A12765 Heat shock reporterRocaglamide是 T 细胞中一种有效的 NF-κB 活化抑制剂。Rocaglamide 是一种有效的选择性热休克因子 1 (HSF1) 活化抑制剂，IC50 约为 50 nM。Rocaglamide 还抑制翻译起始因子 eIF4A 的功能。Rocaglamide 还具有抗癌特性。 了解更多 -
Gedunin
Catalog No. A16034 -
TRC 051384
Catalog No. A16053 HSP70 inducerTRC 051384，属于取代的2-丙烯-1-酮类，是热休克蛋白70（HSP70）的有效诱导剂。HSP70的诱导是应激细胞的自然反应，可保护神经元细胞免受各种损伤，包括急性缺血。 了解更多 -
Nepicastat HCl
Catalog No. A11172 -
Tetrahydropapaverine HCl
Catalog No. A10920 Hydroxylase 抑制剂Tetrahydropapaverine HCl是TIQs的一种，是Salsolinol和Tetrahydropapaveroline的类似物，对多巴胺神经元具有神经毒性作用。 了解更多 -
LX 1606 Hippurate
Catalog No. A10542 Hydroxylase 抑制剂LX 1606 hippurate是一种口服生物可利用的小分子色氨酸羟化酶(TPH)抑制剂，具有潜在的抗旋转能活性。 了解更多 -
Nepicastat (free base) (SYN-117)
Catalog No. A10637 dopamine beta-hydroxylase 抑制剂Nepicastat (free base) (SYN-117)是多巴胺β-羟化酶的抑制剂，该酶催化多巴胺向去甲肾上腺素的转化。 了解更多 -
LX 1606 (Telotristat)
Catalog No. A11785 Serotonin synthesis 抑制剂LX 1606 (Telotristat)是一种口服生物可利用的小分子色氨酸羟化酶（TPH）抑制剂，具有潜在的抗血清素活性。 了解更多 -
Ro 61-8048
Catalog No. A12833 Hydroxylase 抑制剂Ro 61-8048是有效的竞争性犬尿氨酸3-羟化酶抑制剂（Ki = 4.8 nM，IC50 = 37 nM）。 了解更多 -
Collagen proline hydroxylase inhibitor
Catalog No. A11371 -
LCI-699 (Osilodrostat)
Catalog No. A14013 11β-hydroxylase 抑制剂LCI-699 (Osilodrostat)是人11β-羟化酶和醛固酮合酶的有效抑制剂，IC50值分别为2.5和0.7 nM。 了解更多 -
4-Chloro-DL-phenylalanine
Catalog No. A16424 Tryptophan hydroxylase 抑制剂4-Chloro-DL-phenylalanine是色氨酸羟化酶的选择性和不可逆抑制剂，色氨酸羟化酶是5-羟色胺（5-羟色胺）生物合成中的限速酶。 了解更多 -
Fondaparinux Sodium
Catalog No. A17918 factor Xa inhibitorFondaparinux sodium is a factor Xa inhibitor to form the high affinity binding site for the anti-coagulant factor antithrombin III (ATIII). 了解更多 -
RWJ-445167
Catalog No. A12154 dual inhibitor of thrombin and factor XaRWJ-445167 (3DP-10017) is a dual inhibitor of thrombin and factor Xa with Ki of 4.0 nM and 230 nM, respectively, exhibiting potent antithrombotic activity. 了解更多 -
BMS-654457
Catalog No. A21704 Factor XIa (FXIa) inhibitorBMS-654457 is a small-molecule, reversible inhibitor of factor XIa (FXIa), binding with human and rabbit FXIa with Kis of 0.2 and 0.42 nM, respectively. 了解更多 -
Apixaban (BMS-562247-01)
Catalog No. A10082 Factor Xa 抑制剂Apixaban (BMS-562247-01)是一种抗凝剂，用于预防静脉血栓栓塞和静脉血栓栓塞事件。 了解更多 -
BMS-740808
Catalog No. A10158 -
Rivaroxaban (Xarelto)
Catalog No. A10800 Factor Xa 抑制剂Rivaroxaban (Xarelto)是一种Factor Xa的直接抑制剂，无细胞试验中Ki和IC50分别为0.4 nM和0.7 nM。 了解更多 -
Otamixaban (FXV 673)
Catalog No. A11517 -
Letaxaban (TAK-442)
Catalog No. A12871 factor Xa 抑制剂Letaxaban (TAK-442)是一种有效的，选择性的，口服活性的Xa抑制剂，是一种四氢嘧啶-2（1H）-衍生物。TAK-442在贫血小板的人[半最大抑制浓度（IC（50））：53 nM，TAK-442]和大鼠（IC（50）：32 nM，TAK-442）血浆中抑制内源性FXa活性。 了解更多
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