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￥ 0.00 Cell Metabolism
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T0070907
Catalog No. A11588 -
Aleglitazar
Catalog No. A12492 -
Elafibranor
Catalog No. A15454 PPAR 激动剂Elafibranor是过氧化物酶体增殖物激活的受体-α和-δ的激动剂，可诱导非酒精性脂肪性肝炎消退，而不会使纤维化恶化。 了解更多 -
CDDO-Im
Catalog No. A16308 -
DG172 dihydrochloride
Catalog No. A16309 PPARβ/δ inverse 激动剂DG-172是一种口服活性强效PPARβ/δ反向激动剂 (IC50 = 26.9 nM)。DG-172在体外抑制小鼠成肌细胞中Angptl4基因的表达 (IC50 = 9.5 nM)。 了解更多 -
5-Aminosalicylic Acid
Catalog No. A10570 PPARγ agonist5-Aminosalicylic acid (Mesalamine) acts as a specific PPARγ agonist and also inhibits p21-activated kinase 1 (PAK1) and NF-κB. 了解更多 -
Pioglitazone hydrochloride
Catalog No. A16670 PPARγ agonistPioglitazone hydrochloride is a potent and selective PPARγ agonist with EC50s of 0.93 and 0.99 μM for human and mouse PPARγ, respectively. 了解更多 -
Fonadelpar
Catalog No. A20848 PPARδ agonistFonadelpar is a PPARδ agonist, used in the research of neuroparalytic keratopathy. 了解更多 -
Tesaglitazar
Catalog No. A20891 PPAR alpha/gamma agonistTesaglitazar is a dual peroxisome proliferator-activated receptor (PPAR) alpha/gamma agonist that is more potent on PPARγ than on PPARα, with EC50s of 13.4 μM and 3.6 μM for rat PPARα and human PPARα, respectively. 了解更多 -
Arhalofenate
Catalog No. A21135 PPARγ agonistArhalofenate (MBX 102) is a selective partial agonist of peroxisome proliferator-activated receptor (PPAR)-γ, used for the treatment of type 2 diabetes. 了解更多 -
Indeglitazar
Catalog No. A21148 PPAR agonistIndeglitazar is an orally available peroxisome proliferator-activated receptor (PPAR) pan-agonist for all three PPAR subtypes alpha (α), delta (δ) and gamma (γ). 了解更多 -
Inolitazone
Catalog No. A21180 PPARγ agonistInolitazone a novel high-affinity PPARγ agonist that is dependent upon PPARγ for its biological activity with IC50 of 0.8 nM for growth inhibition. 了解更多 -
Peliglitazar racemate
Catalog No. A21411 dual α/γ PPAR activatorPeliglitazar racemate is the racemate of Peliglitazar. Peliglitazar is a novel dual α/γ PPAR activator. 了解更多 -
TAK-700 (Orteronel)
Catalog No. A11044 -
Voriconazole (Vfend)
Catalog No. A10978 -
Abiraterone (CB-7598)
Catalog No. A10020 -
Abiraterone Acetate (CB7630)
Catalog No. A11058 -
Avasimibe (CI-1011)
Catalog No. A10102 CYP17 抑制剂Avasimibe (CI-1011)是口服可生物利用的酰基辅酶A：胆固醇O-酰基转移酶（ACAT）抑制剂，IC50分别为2.9 μM， 13.9 μM和26.5 μM。 了解更多 -
TOK-001 (Galeterone)
Catalog No. A11138 -
TH-302 (Evofosfamide)
Catalog No. A11144 TH-302 (Evofosfamide)是选择性靶向实体瘤缺氧激活的前体药物，靶向作用于实体瘤的hypoxic区域，IC50为19 nM，在缺氧条件下比在有氧条件下细胞毒性增强270倍，细胞色素P450代谢稳定。 了解更多 -
Naringenin
Catalog No. A10625 Naringenin是一种黄烷酮，是一种类黄酮，被认为具有抗氧化剂，自由基清除剂，消炎，碳水化合物代谢促进剂和免疫系统调节剂等对人体健康的生物活性。 了解更多 -
Sodium Danshensu
Catalog No. A10853 Sodium danshensu是来自广泛使用的中草药丹参（丹参）的丹参素的钠盐。体外和体内研究表明，丹参素具有多种药理作用，包括舒张冠状动脉，抗凝，保护心肌缺血-再灌注损伤和抗心律不齐活动 了解更多 -
Cyproterone acetate
Catalog No. A11409 Androgen Receptor 拮抗剂Cyproterone acetate是17-羟孕酮的合成衍生物，可作为雄激素受体拮抗剂以及具有弱孕激素和糖皮质激素活性的弱孕激素受体激动剂。 了解更多 -
Posaconazole
Catalog No. A10744 CYP3A4 抑制剂Posaconazole主要是CYP3A4的抑制剂，但不抑制其他CYP酶的活性。也是甾醇C14+脱甲基酶抑制剂的抑制剂，IC50为0.25μM。泊沙康唑的终末消除半衰期中位数为15-35小时。 了解更多 -
Ketoconazole
Catalog No. A10498 -
Cobicistat (GS-9350)
Catalog No. A11277 CYP3A 抑制剂Cobicistat (GS-9350)是有效，选择性的细胞色素酶P450 3A (CYP3A)抑制剂，包括重要的cyp3a4亚型。它还抑制肠道转运蛋白，增加几种hiv药物的整体吸收，包括atazanavir、darunavir和tenofovir alafenamide延胡索酸盐。 了解更多 -
Clotrimazole
Catalog No. A10234 clotrimazole的作用是对抗真菌的分裂和生长。clotrimazole改变真菌细胞壁的通透性并抑制细胞内酶的活性。 它特别抑制麦角固醇和细胞膜生产所需的其他固醇的生物合成。 了解更多 -
Deferasirox
Catalog No. A10293 Iron chelatorDeferasirox是一种铁螯合剂，也是细胞色素P450 3A4诱导剂，细胞色素P450 2C8抑制剂和细胞色素P450 1A2抑制剂。 了解更多 -
Itraconazole (Sporanox)
Catalog No. A10489 Itraconazole (Sporanox)是CYP3A4相对有效的抑制剂，IC50为6.1nM，用作三唑类抗真菌剂。 了解更多 -
Methoxsalen (Oxsoralen)
Catalog No. A10578 Methoxsalen (8-Methoxypsoralen)是一种有效的CYP三环呋喃香豆素自杀抑制剂（细胞色素P-450）。 了解更多
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