Cell Metabolism
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Olumacostat glasaretil
Catalog No. A20840 ACC inhibitorOlumacostat glasaretil is a small molecule inhibitor of acetyl coenzyme A carboxylase (ACC). 了解更多 -
PF-05175157
Catalog No. A21460 ACC inhibitorPF-05175157 is broad spectrum acetyl-CoA carboxylase (ACC) inhibitor with IC50s of 27.0, 33.0, 23.5 and 50.4 nM for ACC1 (human), ACC2 (human), ACC1 (rat), ACC2 (rat), respectively. 了解更多 -
CP-640186 hydrochloride
Catalog No. A21808 ACC inhibitorCP-640186 hydrochloride is a potent and cell-permeable Acetyl-CoA carboxylase (ACC) inhibitor with IC50s of 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively. 了解更多 -
Firsocostat
Catalog No. A21000 ACC inhibitorFirsocostat (ND-630; GS-0976; NDI-010976) is an acetyl-CoA carboxylase (ACC) inhibitor; inhibits human ACC1 and ACC2 with IC50 values of 2.1 and 6.1 nM, respectively. 了解更多 -
Miglitol (Glyset)
Catalog No. A11678 Miglitol inhibits称为α-葡萄糖苷酶的糖苷水解酶。 它主要用于2型糖尿病,可通过阻止碳水化合物(例如二糖,寡糖和多糖)消化成可被人体吸收的单糖来建立更好的血糖控制。 了解更多 -
Miglustat hydrochloride
Catalog No. A12797 Miglustat hydrochloride是一种口服活性的α-葡萄糖苷酶Ⅰ和Ⅱ以及神经酰胺特异性糖基转移酶抑制剂。 了解更多 -
Celgosivir
Catalog No. A13118 -
Afegostat D-tartrate
Catalog No. A14385 Afegostat D-tartrate是用于治疗某些形式的高雪氏病的实验药物。该物质以酒石酸盐的形式使用。异黄酮(IFG)是一种酸性β-葡萄糖苷酶(GCase)活性位点抑制剂,可作为药理伴侣。 了解更多 -
Deoxynojirimycin
Catalog No. A14383 -
Licochalcone C
Catalog No. A14848 Licochalcone C 能够抑制 α-葡萄糖苷酶 (α-glucosidase),其对 α-葡萄糖苷酶和蛋白酪氨酸磷酸酶 1B 的 IC50 值分别为 <100 nM 和 92.43 μM。 了解更多 -
Terphenyllin
Catalog No. A18967 Terphenyllin is a naturally abundant p-terphenyl metabolite isolated from the coral derived fungus Aspergillus candidus, has signi?cant α-glucosidase inhibitory activity. 了解更多 -
SHP099 hydrochloride
Catalog No. A21762 SHP2 inhibitorSHP099 hydrochloride is a potent, selective and orally available SHP2 inhibitor with an IC50 of 70 nM. 了解更多 -
IACS-13909
Catalog No. A22159 SHP2 allosteric inhibitorIACS-13909 is a selective, potent and orally active SHP2 allosteric inhibitor with an IC50 of 15.7 nM and a Kd of 32 nM. 了解更多