Cell Metabolism

产品 601 到 623 共 623个

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  1. TOFA

    Catalog No. A12276
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    ACCA inhibitor
    TOFA (RMI14514;MDL14514) is an allosteric inhibitor of acetyl-CoA carboxylase-α (ACCA ). 了解更多
  2. Olumacostat glasaretil

    Catalog No. A20840
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    ACC inhibitor
    Olumacostat glasaretil is a small molecule inhibitor of acetyl coenzyme A carboxylase (ACC). 了解更多
  3. PF-05175157

    Catalog No. A21460
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    ACC inhibitor
    PF-05175157 is broad spectrum acetyl-CoA carboxylase (ACC) inhibitor with IC50s of 27.0, 33.0, 23.5 and 50.4 nM for ACC1 (human), ACC2 (human), ACC1 (rat), ACC2 (rat), respectively. 了解更多
  4. CP-640186 hydrochloride

    Catalog No. A21808
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    ACC inhibitor
    CP-640186 hydrochloride is a potent and cell-permeable Acetyl-CoA carboxylase (ACC) inhibitor with IC50s of 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively. 了解更多
  5. Firsocostat

    Catalog No. A21000
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    ACC inhibitor
    Firsocostat (ND-630; GS-0976; NDI-010976) is an acetyl-CoA carboxylase (ACC) inhibitor; inhibits human ACC1 and ACC2 with IC50 values of 2.1 and 6.1 nM, respectively. 了解更多
  6. Acarbose

    Catalog No. A10029
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    Anti-Diabetic Agent
    Acarbose是一种肠道alpha-glucosidase抑制剂,用于治疗2型糖尿病以及某些国家的前驱糖尿病。 了解更多
  7. Miglitol (Glyset)

    Catalog No. A11678
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    Miglitol inhibits称为α-葡萄糖苷酶的糖苷水解酶。 它主要用于2型糖尿病,可通过阻止碳水化合物(例如二糖,寡糖和多糖)消化成可被人体吸收的单糖来建立更好的血糖控制。 了解更多
  8. Miglustat hydrochloride

    Catalog No. A12797
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    Miglustat hydrochloride是一种口服活性的α-葡萄糖苷酶Ⅰ和Ⅱ以及神经酰胺特异性糖基转移酶抑制剂。 了解更多
  9. Celgosivir

    Catalog No. A13118
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    alpha-glucosidase I 抑制剂
    Celgosivir是一种用于潜在治疗HCV感染的α-葡萄糖苷酶I抑制剂。 了解更多
  10. Vitexin

    Catalog No. A12135
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    Vitexin在dpph漂白试验中表现出抗氧化活性(IC50 = 24.2uM),并且还抑制碳水化合物水解酶α-葡萄糖苷酶的活性(IC50 = 244 uM)。 了解更多
  11. Afegostat D-tartrate

    Catalog No. A14385
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    Afegostat D-tartrate是用于治疗某些形式的高雪氏病的实验药物。该物质以酒石酸盐的形式使用。异黄酮(IFG)是一种酸性β-葡萄糖苷酶(GCase)活性位点抑制剂,可作为药理伴侣。 了解更多
  12. Deoxynojirimycin

    Catalog No. A14383
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    glucosidase I/II 抑制剂
    Deoxynojirimycin是马耳他酶-葡糖淀粉酶(α-葡糖苷酶I和II)抑制剂。它干扰N-连接的糖基化。 了解更多
  13. 3-Butylidenephthalide

    Catalog No. A14633
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    3-Butylidenephthalide是一种α-葡萄糖苷酶抑制剂。 了解更多
  14. Licochalcone C

    Catalog No. A14848
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    Licochalcone C 能够抑制 α-葡萄糖苷酶 (α-glucosidase),其对 α-葡萄糖苷酶和蛋白酪氨酸磷酸酶 1B 的 IC50 值分别为 <100 nM 和 92.43 μM。 了解更多
  15. Voglibose

    Catalog No. A14945
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    alpha-glucosidase 抑制剂
    Voglibose是缬氨酰胺的N取代衍生物,对α-葡萄糖苷酶具有出色的抑制活性,并且对高血糖症和由高血糖症引起的各种疾病具有抗药性。 了解更多
  16. Terphenyllin

    Catalog No. A18967
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    Terphenyllin is a naturally abundant p-terphenyl metabolite isolated from the coral derived fungus Aspergillus candidus, has signi?cant α-glucosidase inhibitory activity. 了解更多
  17. Afegostat

    Catalog No. A21137
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    Afegostat is a pharmacological chaperone, which specifically and reversibly binds acid-β-glucosidase (GCase) in the endoplasmic reticulum (ER) with high affinity. 了解更多
  18. RMC-4550

    Catalog No. A18893
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    SHP2 inhibitor
    RMC-4550 is a potent, selective and allosteric inhibitor of SHP2, with an IC50 of 0.583 nM. 了解更多
  19. SHP394

    Catalog No. A18613
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    SHP2 inhibitor
    SHP394 is an orally efficacious protein tyrosine phosphatase SHP2 inhibitor with an IC50 of 23 nM. 了解更多
  20. SHP2 IN-1

    Catalog No. A19099
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    SHP2 (PTPN11) inhibitor
    SHP2 IN-1 (compound 13) is an allergic inhibitor of SHP2 (PTPN11), with an IC50 of 3 nM. 了解更多
  21. SHP099 hydrochloride

    Catalog No. A21762
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    SHP2 inhibitor
    SHP099 hydrochloride is a potent, selective and orally available SHP2 inhibitor with an IC50 of 70 nM. 了解更多
  22. SHP099

    Catalog No. A20594
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    SHP2 inhibitor
    SHP099 is a potent, selective, orally available SHP2 inhibitor with an IC50 of 70 nM. 了解更多
  23. IACS-13909

    Catalog No. A22159
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    SHP2 allosteric inhibitor
    IACS-13909 is a selective, potent and orally active SHP2 allosteric inhibitor with an IC50 of 15.7 nM and a Kd of 32 nM. 了解更多

产品 601 到 623 共 623个

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