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CEP-1347是c-jun N末端激酶（JNK）信号传导的抑制剂。 它可以挽救经历凋亡的运动神经元（EC50 = 20 nM）。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 16.24 mL | 81.2 mL | 162.4 mL |
| 0.5 mM | 3.25 mL | 16.24 mL | 32.48 mL |
| 1 mM | 1.62 mL | 8.12 mL | 16.24 mL |
| 5 mM | 0.32 mL | 1.62 mL | 3.25 mL |
*The above data is based on the productmolecular weight 615.76. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A13565 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 615.76 |
| Formula | C33H33N3O5S2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 156177-65-0 |
| Synonyms | 3,9-Bis(etsm)-K-252a, CEP 1347, CEP-1347, CEP1347, KT 7515 |
| SMILES | CCSCC1=CC2=C(C=C1)N3[C@@H]4C[C@@H]([C@](O4)(N5C6=C(C=C(C=C6)CSCC)C7=C8CNC(=O)C8=C2C3=C75)C)C(=O)OOC |
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