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CGP 36742 is a selective GABAB receptor antagonist that can penetrate the blood?Cbrain barrier after peripheral administration, with an IC50 of 32?μM. CGP 36742 is useful in treatment of depression.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 55.8 mL | 279.02 mL | 558.04 mL |
| 0.5 mM | 11.16 mL | 55.8 mL | 111.61 mL |
| 1 mM | 5.58 mL | 27.9 mL | 55.8 mL |
| 5 mM | 1.12 mL | 5.58 mL | 11.16 mL |
*The above data is based on the productmolecular weight 179.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A18666 |
|---|---|
| 作用机制 | Antagonist (拮抗剂) |
| M. Wt | 179.2 |
| Formula | C7H18NO2P |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 123690-78-8 |
| Synonyms | CGP 36742; CGP36742; CGP-36742. |
| SMILES | O=P(CCCN)(O)CCCC |
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