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CHC是单羧酸转运（MCT）抑制剂。在神经胶质瘤中具有抗肿瘤和抗血管生成活性；降低U251细胞的糖酵解代谢，迁移和侵袭。
| In vitro | DMSO | 32 mg/mL (169.16 mM) | |
| Water | Insoluble | ||
| Ethanol | 7 mg/mL (37 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 52.86 mL | 264.31 mL | 528.63 mL |
| 0.5 mM | 10.57 mL | 52.86 mL | 105.73 mL |
| 1 mM | 5.29 mL | 26.43 mL | 52.86 mL |
| 5 mM | 1.06 mL | 5.29 mL | 10.57 mL |
*The above data is based on the productmolecular weight 189.17. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A13372 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 189.17 |
| Formula | C10H7NO3 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 28166-41-8 |
| Synonyms | -Cyano-4-hydroxycinnamic acid |
| SMILES | C1=CC(=CC=C1/C=C(\C#N)/C(=O)O)O |
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