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Cilengitide trifluoroacetate

Cilengitide trifluoroacetate

Name: Cilengitide trifluoroacetate
SKU: A12371

目录号: A12371

Integrin 抑制剂

Product Citations (1)

Cilengitide trifluoroacetate Chemical Structure

CAS NO. 199807-35-7

Cilengitide trifluoroacetate是一种具有潜在抗肿瘤活性的环状精氨酸-甘氨酸-天冬氨酸肽。西仑吉肽结合并抑制α(v)β(3)和α(v)β(5)整联蛋白的活性，从而抑制内皮细胞-细胞相互作用、内皮细胞-基质相互作用和血管生成。

库存：现货

规格	价格	数量
5 mg	￥ 1,050.00
10 mg	￥ 1,400.00
25 mg	￥ 2,450.00
50 mg	￥ 4,200.00

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生物活性

靶点信息

αvβ3 receptor (Cell-free assay)	αvβ5 receptor (Cell-free assay)
4.1 nM	79 nM

溶解度 *

In vitro	DMSO	89 mg/mL (126.66 mM)
	Water	7 mg/mL (9.96 mM)
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	14.23 mL	71.15 mL	142.31 mL
0.5 mM	2.85 mL	14.23 mL	28.46 mL
1 mM	1.42 mL	7.12 mL	14.23 mL
5 mM	0.28 mL	1.42 mL	2.85 mL

*The above data is based on the productmolecular weight 702.7. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A12371
作用机制	Inhibitor (抑制剂)
M. Wt	702.7
Formula	C29H41N8O9F3
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	199807-35-7
Synonyms	EMD 12197,EMD-85189,EMD-121974,NSC-707544,D03497
SMILES	CC(C)[C@H]1C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](C(=O)N1C)Cc2ccccc2)CC(=O)O)CCCNC(=N)N.C(=O)(C(F)(F)F)O