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Cilnidipine是提供血管平滑肌中L型电压门控钙通道和交感神经末梢N型钙通道的双重阻滞剂。
靶点信息
| Calcium channel | ||||
| In vitro (25°C) | DMSO | 90 mg/mL (182.73 mM) | |
| Water | Insoluble | ||
| Ethanol | 14 mg/mL (28.42 mM) | ||
| In vivo | 5% DMSO+corn oil | 6 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.3 mL | 101.52 mL | 203.04 mL |
| 0.5 mM | 4.06 mL | 20.3 mL | 40.61 mL |
| 1 mM | 2.03 mL | 10.15 mL | 20.3 mL |
| 5 mM | 0.41 mL | 2.03 mL | 4.06 mL |
*The above data is based on the productmolecular weight 492.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A10215 |
|---|---|
| 作用机制 | Blocker (阻断剂) |
| M. Wt | 492.52 |
| Formula | C27H28N2O7 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 132203-70-4 |
| Synonyms | FRC 8653 |
| SMILES | CC1=C(C(C(=C(N1)C)C(=O)OC/C=C/C2=CC=CC=C2)C3=CC(=CC=C3)[N+](=O)[O-])C(=O)OCCOC |
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