产品详情
CKD-519 is a selective and potent cholesteryl ester transfer protein (CETP) inhibitor being developed for the treatment of dyslipidemia to raise high-density lipoprotein cholesterol. Single doses of CKD-519 up to 400 mg were well tolerated and showed potent inhibition of CETP activity.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 16.62 mL | 83.11 mL | 166.22 mL |
0.5 mM | 3.32 mL | 16.62 mL | 33.24 mL |
1 mM | 1.66 mL | 8.31 mL | 16.62 mL |
5 mM | 0.33 mL | 1.66 mL | 3.32 mL |
*The above data is based on the productmolecular weight 601.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A18873 |
---|---|
作用机制 | Inhibitor (抑制剂) |
M. Wt | 601.6 |
Formula | C31H34F7NO3 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 1402796-27-3 |
Synonyms | CKD-519; CKD 519; CKD519. |
SMILES | C[C@H]1[C@@H](C2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2)OC(N1CC3=C(CCC(C)(C)C3)C4=C(OC)C=C(F)C(C(C)C)=C4)=O |
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