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Clemastine fumarate是一种选择性的组胺H1拮抗剂。它与组胺H1受体结合，从而阻断了内源性组胺的作用，从而暂时缓解了由组胺引起的阴性症状。
靶点信息
| Histamine H1 receptor | ||||
| 3 nM |
| In vitro | DMSO | Warmed: 31 mg/mL (67.39 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.74 mL | 108.71 mL | 217.41 mL |
| 0.5 mM | 4.35 mL | 21.74 mL | 43.48 mL |
| 1 mM | 2.17 mL | 10.87 mL | 21.74 mL |
| 5 mM | 0.43 mL | 2.17 mL | 4.35 mL |
*The above data is based on the productmolecular weight 459.96. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A10226 |
|---|---|
| M. Wt | 459.96 |
| Formula | C21H26ClNO.C4H4O4 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 14976-57-9 |
| Synonyms | meclastin |
| SMILES | C[C@@](C1=CC=CC=C1)(C2=CC=C(C=C2)Cl)OCC[C@H]3CCCN3C.C(=C/C(=O)O)\C(=O)O |
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