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Cobimetinib R-enantiomer是Cobimetinib的R对映异构体，Cobimetinib是一种有力的，高选择性的促分裂原活化蛋白激酶（MEK1/2）抑制剂。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.82 mL | 94.11 mL | 188.21 mL |
| 0.5 mM | 3.76 mL | 18.82 mL | 37.64 mL |
| 1 mM | 1.88 mL | 9.41 mL | 18.82 mL |
| 5 mM | 0.38 mL | 1.88 mL | 3.76 mL |
*The above data is based on the productmolecular weight 531.31. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A15051 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 531.31 |
| Formula | C21H21F3IN3O2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 934660-94-3 |
| Synonyms | GDC-0973 R-enantiomer, XL-518 R-enantiomer |
| SMILES | C1CCNC(C1)C2(CN(C2)C(=O)C3=C(C(=C(C=C3)F)F)NC4=C(C=C(C=C4)I)F)O |
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