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CPI 4203是KDM5脱甲基酶的选择性抑制剂，在结构上与CPI 455相关，但效力低约25倍（IC50值250 nM用于抑制全长KDM5A）。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 35.93 mL | 179.65 mL | 359.3 mL |
| 0.5 mM | 7.19 mL | 35.93 mL | 71.86 mL |
| 1 mM | 3.59 mL | 17.96 mL | 35.93 mL |
| 5 mM | 0.72 mL | 3.59 mL | 7.19 mL |
*The above data is based on the productmolecular weight 278.32. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A16177 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 278.32 |
| Formula | C16H14N4O |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1628214-07-2 |
| Synonyms | CPI-4203, CPI4203 |
| SMILES | CCC1=C(N=C2C(=CNN2C1=O)C#N)C3=CC=CC=C3C |
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