CRM1
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KPT276
Catalog No. A16341 -
Eltanexor Z-isomer
Catalog No. A21786 CRM1 inhibitorEltanexor Z-isomer (KPT-8602 Z-isomer) is the less active isomer of KPT-8602. KPT-8602 is a potent CRM1 inhibitor. 了解更多 -
Leptomycin B
Catalog No. A20985 nuclear export receptor CRM1 inhibitorLeptomycin B (CI 940; LMB) is a potent inhibitor of the nuclear export of proteins. Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue. Leptomycin B is a potent antifungal antibiotic blocking the eukaryotic cell cycle. 了解更多 -
Selinexor (KPT-330)
Catalog No. A12582 CRM1 抑制剂CRM1(XPO1)介导的核输出的KPT-330抑制剂在T细胞急性淋巴细胞白血病和急性骨髓性白血病的临床前模型中具有选择性的抗白血病活性。 了解更多