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Cyclosporin A

Cyclosporin A

Name: Cyclosporin A
SKU: A10260

目录号: A10260

Product Citations (3)

Cyclosporin A Chemical Structure

CAS NO. 59865-13-3

Cyclosporin A (Cyclosporine A)是一种免疫抑制剂，广泛用于异体后器官移植，以降低免疫系统的活性。

库存：现货

规格	价格	数量
25 mg	￥ 210.00
100 mg	￥ 385.00
200 mg	￥ 525.00
10mM * 1mL in DMSO	￥ 511.00

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生物活性

Cyclosporin A (Cyclosporine A)是一种免疫抑制剂，广泛用于异体后器官移植，以降低免疫系统的活性。

靶点信息

calcineurin (Cell-free assay)
7 nM

溶解度 *

In vitro (25°C)	DMSO	Warmed: 99 mg/mL (82.32 mM)
	Water	Insoluble
	Ethanol	Warmed: 99 mg/mL (82.32 mM)
In vivo	2% DMSO+30% PEG 300+5% Tween 80+ddH2O	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	8.32 mL	41.58 mL	83.15 mL
0.5 mM	1.66 mL	8.32 mL	16.63 mL
1 mM	0.83 mL	4.16 mL	8.32 mL
5 mM	0.17 mL	0.83 mL	1.66 mL

*The above data is based on the productmolecular weight 1202.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A10260
M. Wt	1202.6
Formula	C62H111N11O12
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	59865-13-3
Synonyms	Ciclosporin A, CsA, Ciclosporin, cyclosporine, cyclosporin,
SMILES	CC[C@H]1C(=O)N(CC(=O)N([C@H](C(=O)N[C@H](C(=O)N([C@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N1)[C@@H]([C@H](C)C/C=C/C)O)C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C)C