Cyclosporine

Name: Cyclosporine
SKU: A15434

目录号: A15434

Calcineurin 抑制剂

Cyclosporine Chemical Structure

CAS NO. 79217-60-0

Cyclosporine是一种钙调磷酸酶磷酸酶途径抑制剂，用作免疫抑制剂以防止器官移植中的排斥反应。

库存：现货

规格	价格	数量
100 mg	￥ 840.00
250 mg	￥ 1,750.00

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生物活性

Cyclosporine是一种钙调磷酸酶磷酸酶途径抑制剂，用作免疫抑制剂以防止器官移植中的排斥反应。

靶点信息

calcineurin phosphatase

溶解度 *

In vitro (25°C)	DMSO	Warmed: 85 mg/mL (70.68 mM)
	Water	Insoluble
	Ethanol	85 mg/mL (70.68 mM)
In vivo	2% DMSO+40% PEG 300+2% Tween 80+ddH2O	2 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	8.32 mL	41.58 mL	83.15 mL
0.5 mM	1.66 mL	8.32 mL	16.63 mL
1 mM	0.83 mL	4.16 mL	8.32 mL
5 mM	0.17 mL	0.83 mL	1.66 mL

*The above data is based on the productmolecular weight 1202.61. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A15434
作用机制	Inhibitor (抑制剂)
M. Wt	1202.61
Formula	C62H111N11O12
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	79217-60-0
SMILES	CCC1C(=O)N(CC(=O)N(C(C(=O)NC(C(=O)N(C(C(=O)NC(C(=O)NC(C(=O)N(C(C(=O)N(C(C(=O)N(C(C(=O)N(C(C(=O)N1)C(C(C)CC=CC)O)C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C)C