Cytochrome P450
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Seviteronel
Catalog No. A20996 CYP17 lyase inhibitorSeviteronel (VT-464) is a potent CYP17 lyase inhibitor(h-Lyase IC50=69 nM) that demonstrated both exceptional in vitro lyase/hydroxylase selectivity (~10-fold) and oral activity in a hamster model of androgen biosynthesis inhibition. 了解更多 -
CYP17-IN-1
Catalog No. A12622 CYP17 inhibitorCYP17-IN-1 (compound 9c) is a potent and orally active CYP17 inhibitor against rat and human CYP17 with IC50s of 15.8 and 20.1 nM. 了解更多 -
Sulfaphenazole
Catalog No. A17283 CYP2C9 inhibitorSulfaphenazole is a specific inhibitor of CYP2C9 which blocks atherogenic and pro-inflammatory effects of linoleic acid (increase in oxidative stress and activation of AP-1) mediated by CYP2C9. 了解更多 -
Efavirenz
Catalog No. A15826 -
Talarozole R enantiomer
Catalog No. A13113 Cytochrome P450 抑制剂Talarozole R enantiomer 通过阻断细胞色素P450酶同工酶CYP26(一种视黄酸羟化酶)来抑制视黄酸的代谢。 了解更多 -
Haloperidol (Haldol)
Catalog No. A10446 -
Clarithromycin
Catalog No. A10225 cytochrome P4503A4 抑制剂Clarithromycin是一种大环内酯类抗生素。它通过干扰细菌的蛋白质合成来防止细菌生长。 了解更多