微信关注
Total item
Cart Subtotal
￥ 0.00 Cytochrome P450
29 个项目
每页
-
Seviteronel
Catalog No. A20996 CYP17 lyase inhibitorSeviteronel (VT-464) is a potent CYP17 lyase inhibitor(h-Lyase IC50=69 nM) that demonstrated both exceptional in vitro lyase/hydroxylase selectivity (~10-fold) and oral activity in a hamster model of androgen biosynthesis inhibition. 了解更多 -
Liarozole dihydrochloride
Catalog No. A21853 CYP450 dependent inhibitorLiarozole dihydrochloride (R75251; R85246) is a cytochrome P450 (CYP450) dependent inhibitor, orally active, it also a potent inhibitor of estrogen (via inhibition of aromatase) and testicular androgen synthesis (inhibition of 17 ,20-lyase). 了解更多 -
CYP17-IN-1
Catalog No. A12622 CYP17 inhibitorCYP17-IN-1 (compound 9c) is a potent and orally active CYP17 inhibitor against rat and human CYP17 with IC50s of 15.8 and 20.1 nM. 了解更多 -
Sulfaphenazole
Catalog No. A17283 CYP2C9 inhibitorSulfaphenazole is a specific inhibitor of CYP2C9 which blocks atherogenic and pro-inflammatory effects of linoleic acid (increase in oxidative stress and activation of AP-1) mediated by CYP2C9. 了解更多 -
Efavirenz
Catalog No. A15826 -
Talarozole R enantiomer
Catalog No. A13113 Cytochrome P450 抑制剂Talarozole R enantiomer 通过阻断细胞色素P450酶同工酶CYP26（一种视黄酸羟化酶）来抑制视黄酸的代谢。 了解更多 -
Haloperidol (Haldol)
Catalog No. A10446 -
Clarithromycin
Catalog No. A10225 cytochrome P4503A4 抑制剂Clarithromycin是一种大环内酯类抗生素。它通过干扰细菌的蛋白质合成来防止细菌生长。 了解更多 -
PF 4981517
Catalog No. A12544 CYP3A4 抑制剂PF 4981517是一种有效且选择性的CYP3A4抑制剂（CYP3A4，CYP3A5和CYP3A7的IC50值分别为0.03、17和70 μM）。 了解更多 -
Ozagrel(OKY-046)
Catalog No. A10688 -
TAK-700 Salt (Orteronel Salt)
Catalog No. A13515 CYP17A1/androgen synthesis 抑制剂TAK-700 Salt (Orteronel Salt)是一种雄激素合成抑制剂。它选择性地抑制在睾丸，肾上腺和前列腺肿瘤组织中表达的酶CYP17A。 了解更多 -
Choline Fenofibrate
Catalog No. A15044 -
Azathramycin
Catalog No. A15010 -
Benzbromarone
Catalog No. A16201 -
TOK-001 (Galeterone)
Catalog No. A11138 -
Avasimibe (CI-1011)
Catalog No. A10102 CYP17 抑制剂Avasimibe (CI-1011)是口服可生物利用的酰基辅酶A：胆固醇O-酰基转移酶（ACAT）抑制剂，IC50分别为2.9 μM， 13.9 μM和26.5 μM。 了解更多 -
Abiraterone Acetate (CB7630)
Catalog No. A11058 -
Abiraterone (CB-7598)
Catalog No. A10020 -
Voriconazole (Vfend)
Catalog No. A10978 -
TAK-700 (Orteronel)
Catalog No. A11044 -
Posaconazole
Catalog No. A10744 CYP3A4 抑制剂Posaconazole主要是CYP3A4的抑制剂，但不抑制其他CYP酶的活性。也是甾醇C14+脱甲基酶抑制剂的抑制剂，IC50为0.25μM。泊沙康唑的终末消除半衰期中位数为15-35小时。 了解更多 -
Ketoconazole
Catalog No. A10498 -
Cobicistat (GS-9350)
Catalog No. A11277 CYP3A 抑制剂Cobicistat (GS-9350)是有效，选择性的细胞色素酶P450 3A (CYP3A)抑制剂，包括重要的cyp3a4亚型。它还抑制肠道转运蛋白，增加几种hiv药物的整体吸收，包括atazanavir、darunavir和tenofovir alafenamide延胡索酸盐。 了解更多
29 个项目
每页