Cytoskeleton
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Docetaxel (Taxotere)
Catalog No. A10326 Microtubule Associated 抑制剂Docetaxel (Taxotere)多西他赛一种taxol类似物,是一种microtubules解聚抑制剂,通过结合于稳定的微管发挥作用。 了解更多 -
Paclitaxel (Taxol)
Catalog No. A10689 Microtubule Associated 抑制剂Paclitaxel (Taxol)是一种有丝分裂抑制剂,可稳定微管,从而干扰细胞分裂过程中微管的正常分解,在人内皮细胞中IC50为0.1pM。 了解更多 -
Epothilone A
Catalog No. A10359 Microtubule Associated 抑制剂Epothilone A 通过稳定紫杉醇结合位点处的微管形成而起作用,并导致细胞周期停滞在G2/M转变,从而导致细胞毒性。 了解更多 -
Epothilone B (EPO906)
Catalog No. A10360 Microtubule Associated 抑制剂Epothilone B (EPO906)是一种紫杉醇样microtubule稳定剂。 了解更多 -
Vinflunine Tartrate
Catalog No. A10975 Microtubule Associated 抑制剂Vinflunine Tartrate是长春氟宁的酒石酸盐,它使微管不稳定,IC50为18.8 nM,并在细胞分裂过程中干扰微管的动力学。 了解更多 -
CYT997 (Lexibulin)
Catalog No. A10264 Microtubule 抑制剂CYT997 (Lexibulin)是一种新型的抗癌血管分裂剂(VDA)。在体外,CYT997被证明可有效抑制血管内皮生长因子刺激的人脐静脉内皮细胞(IC(50)3.7±1.8 nM)的增殖,并在100 nM时引起明显的形态变化,包括膜起泡。 了解更多 -
ABT-751 (E-7010)
Catalog No. A10024 Microtubule Associated 抑制剂ABT-751 (E-7010)是一种抗有丝分裂剂,可抑制微管聚合,并在秋水仙碱位点与β-微管蛋白结合。在G2M期阻断细胞周期并诱导凋亡。 了解更多 -
Ixabepilone
Catalog No. A11449 -
Nocodazole
Catalog No. A13219 -
4-Demethylepipodophyllotoxin
Catalog No. A10014 -
CK-636
Catalog No. A13827 -
Cabazitaxel
Catalog No. A11831 Microtubule Associated 抑制剂Cabazitaxel是一种天然紫杉烷的半合成衍生物。Cabazitaxel联合泼尼松是基于多西他赛的激素难治性前列腺癌的治疗选择。 了解更多 -
CW069
Catalog No. A13735 -
Cucurbitacin B
Catalog No. A14665 Microtubule polymerization 抑制剂Cucurbitacin B是一种天然的三萜类化合物,以其强大的抗癌活性而闻名,研究表明该化合物抑制JAK/STAT3途径。也是一种有效的微管聚合抑制剂。 了解更多 -
Vc-MMAD
Catalog No. A15273 -
D-64131
Catalog No. A14442 -
Vinblastine sulfate
Catalog No. A13661 microtubule dynamics 抑制剂Vinblastine sulfate在无细胞试验中抑制微管形成并抑制nAChR活性,IC50为8.9μM,用于治疗某些类型的癌症。 了解更多 -
TRx0237 (LMTX) mesylate
Catalog No. A16124 tau protein aggregation 抑制剂TRx0237 (LMTX) mesylate是第二代tau蛋白聚集抑制剂,可用于治疗阿尔茨海默氏病(AD)和额颞痴呆。 了解更多 -
Tasidotin hydrochloride
Catalog No. A21944 microtubule assembly and microtubule dynamics inhibitorTasidotin hydrochloride is a peptide analog of the antimitotic depsipeptide dolastatin 15, as an inhibitor of microtubule assembly and microtubule dynamics. 了解更多 -
CK-666
Catalog No. A20973 Arp2/3 complex inhibitorCK-666 is a cell-permeable inhibitor of actin-related protein Arp2/3 complex, and binds to Arp2/3 complex, stabilizes the inactive state of the complex, blocking movement of the Arp2 and Arp3 subunits into the activated filament-like (short pitch) conformation. 了解更多 -
Entasobulin
Catalog No. A21027 ??-tubulin polymerization inhibitorEntasobulin is a β-tubulin polymerization inhibitor with potential anticancer activity. 了解更多 -
PF-3758309
Catalog No. A11930 -
NVS-PAK1-1
Catalog No. A12708 allosteric PAK1 inhibitorNVS-PAK1-1 is a potent and selective allosteric PAK1 inhibitor with an IC50 of 5 nM. 了解更多 -
Dynamin inhibitory peptide
Catalog No. A14867 -
Carotegrast
Catalog No. A21997 α4 integrin receptor inhibitorCarotegrast is an orally available α4 integrin receptor inhibitor with anti-inflammatories activities. 了解更多 -
Cyclo(RGDyK)
Catalog No. A21819 αVβ3 integrin inhibitorCyclo(RGDyK) is a potent and selective αVβ3 integrin inhibitor with an IC50 of 20 nM. 了解更多 -
Cilengitide
Catalog No. A12372 Integrin 抑制剂Cilengitide是一种具有潜在抗肿瘤活性的环状精氨酸-甘氨酸-天冬氨酸肽。西仑吉肽结合并抑制α(v)β(3)和α(v)β(5)整联蛋白的活性,从而抑制内皮细胞-细胞相互作用、内皮细胞-基质相互作用和血管生成。 了解更多 -
Cilengitide trifluoroacetate
Catalog No. A12371 Integrin 抑制剂Cilengitide trifluoroacetate是一种具有潜在抗肿瘤活性的环状精氨酸-甘氨酸-天冬氨酸肽。西仑吉肽结合并抑制α(v)β(3)和α(v)β(5)整联蛋白的活性,从而抑制内皮细胞-细胞相互作用、内皮细胞-基质相互作用和血管生成。 了解更多 -
Cyclo (-RGDfK)
Catalog No. A14923 -
RGD (Arg-Gly-Asp) Peptides
Catalog No. A15538 Inhibits integrin binding to RGD motifsRGD (Arg-Gly-Asp) Peptides是一种细胞粘附基序,可以模拟细胞粘附蛋白并与整联蛋白结合。 了解更多 -
Cyclo (RGDyK) trifluoroacetate
Catalog No. A15918