CZC24832

Name: CZC24832
SKU: A11363

目录号: A11363

PI3K 抑制剂

Product Citations (1)

CZC24832 Chemical Structure

CAS NO. 1159824-67-5

CZC24832是一种有效的选择性PI3Kγ抑制剂(在PI3Kγ依赖性fMLP诱导的中性粒细胞迁移试验中IC50 = 1.0 μM)。

库存：现货

规格	价格	数量
5 mg	￥ 560.00
10 mg	￥ 980.00
25 mg	￥ 1,960.00
50 mg	￥ 3,360.00

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生物活性

CZC24832是一种有效的选择性PI3Kγ抑制剂(在PI3Kγ依赖性fMLP诱导的中性粒细胞迁移试验中IC50 = 1.0 μM)。

靶点信息

PI3Kγ	PI3Kβ	PI3Kδ
27 nM	1.1 μM	8.2 μM

溶解度 *

In vitro (25°C)	DMSO	Warmed: 5 mg/mL (13.72 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	0.5% CMC	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	27.44 mL	137.21 mL	274.42 mL
0.5 mM	5.49 mL	27.44 mL	54.88 mL
1 mM	2.74 mL	13.72 mL	27.44 mL
5 mM	0.55 mL	2.74 mL	5.49 mL

*The above data is based on the productmolecular weight 364.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A11363
作用机制	Inhibitor (抑制剂)
M. Wt	364.4
Formula	C15H17FN6O2S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1159824-67-5
Synonyms	CZC 24832, CZC-24832
SMILES	CC(C)(C)NS(=O)(=O)C1=CN=CC(=C1)C2=CN3C(=NC(=N3)N)C(=C2)F