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D-69491 (SU11464)是一种小分子HER2抑制剂，正在开发中，用于治疗HER2高表达的肿瘤，例如乳腺癌，卵巢癌，肺癌和胰腺癌。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.78 mL | 88.9 mL | 177.8 mL |
| 0.5 mM | 3.56 mL | 17.78 mL | 35.56 mL |
| 1 mM | 1.78 mL | 8.89 mL | 17.78 mL |
| 5 mM | 0.36 mL | 1.78 mL | 3.56 mL |
*The above data is based on the productmolecular weight 562.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A15457 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 562.42 |
| Formula | C25H26Cl2FN7O3 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 346599-65-3 |
| Synonyms | D69491, SU 11464, SU11464, D 69491 |
| SMILES | CC1=C(NC(=C1)C(=O)NCCN2CCOCC2)C=C3C4=C(NC3=O)N=CN=C4NC5=CC(=C(C=C5)F)Cl.Cl |
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