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Dasotraline hydrochloride (SEP-225289 hydrochloride) is a triple reuptake inhibitor that blocks dopamine, norepinephrine, and serotonin transporters with IC50 values of 4, 6, and 11 nM, respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 30.43 mL | 152.13 mL | 304.27 mL |
| 0.5 mM | 6.09 mL | 30.43 mL | 60.85 mL |
| 1 mM | 3.04 mL | 15.21 mL | 30.43 mL |
| 5 mM | 0.61 mL | 3.04 mL | 6.09 mL |
*The above data is based on the productmolecular weight 328.66. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A21684 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 328.66 |
| Formula | C16H16Cl3N |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 675126-08-6 |
| Synonyms | SEP-225289 hydrochloride, SEP225289, SEP 225289 |
| SMILES | N[C@@H]1CC[C@@H](C2=CC=C(Cl)C(Cl)=C2)C3=CC=CC=C31.Cl[H] |
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