DDR1-IN-1

目录号: A13985

DDR1 receptor 抑制剂

DDR1-IN-1

DDR1-IN-1 Chemical Structure

CAS NO. 1449685-96-4

DDR1-IN-1是一种有效的选择性DDR1受体酪氨酸激酶抑制剂,IC50/EC50为105 nM/87 nM,对DDR2的效力低4倍(IC50 = 413 nM)。

库存: 现货

规格 价格 数量
5 mg
¥ 560.00
10 mg
¥ 875.00
25 mg
¥ 1,750.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

DDR1-IN-1是一种有效的选择性DDR1受体酪氨酸激酶抑制剂,IC50/EC50为105 nM/87 nM,对DDR2的效力低4倍(IC50 = 413 nM)。
靶点信息
DDR1 DDR2
105 nM413 nM
In vitro DMSO Warmed: 87 mg/mL (157.44 mM)
Water Insoluble
Ethanol Warmed: 3 mg/mL (5.42 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.1 mL 90.48 mL 180.97 mL
0.5 mM 3.62 mL 18.1 mL 36.19 mL
1 mM 1.81 mL 9.05 mL 18.1 mL
5 mM 0.36 mL 1.81 mL 3.62 mL

*The above data is based on the productmolecular weight 552.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A13985
作用机制 Inhibitor (抑制剂)
M. Wt 552.59
Formula C30H31F3N4O3
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1449685-96-4
SMILES CCN1CCN(CC1)CC2=C(C=C(C=C2)C(=O)NC3=CC(=C(C=C3)C)OC4=CC5=C(C=C4)NC(=O)C5)C(F)(F)F

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