Desvenlafaxine succinate hydrate

Name: Desvenlafaxine succinate hydrate
SKU: A15491

目录号: A15491

serotonin (5-HT)/norepinephrine (NE) reuptake 抑制剂

Desvenlafaxine succinate hydrate Chemical Structure

CAS NO. 386750-22-7

Desvenlafaxine succinate hydrate是一种新型5-羟色胺(5-HT)转运蛋白和去甲肾上腺素(NE)转运蛋白重吸收抑制剂，Ki值分别为40.2 nM和558.4 nM

库存：现货

规格	价格	数量
10 mg	￥ 315.00
25 mg	￥ 539.00
50 mg	￥ 910.00

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生物活性

Desvenlafaxine succinate hydrate是一种新型5-羟色胺(5-HT)转运蛋白和去甲肾上腺素(NE)转运蛋白重吸收抑制剂，Ki值分别为40.2 nM和558.4 nM

靶点信息

5-HT	Norepinephrine (NE)
40.2 nM(Ki)	558.4 nM(Ki)

溶解度 *

In vitro (25°C)	DMSO	76 mg/mL (181.66 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	0.5% methylcellulose+0.2% Tween 80	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	25.03 mL	125.16 mL	250.33 mL
0.5 mM	5.01 mL	25.03 mL	50.07 mL
1 mM	2.5 mL	12.52 mL	25.03 mL
5 mM	0.5 mL	2.5 mL	5.01 mL

*The above data is based on the productmolecular weight 399.48. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A15491
作用机制	Inhibitor (抑制剂)
M. Wt	399.48
Formula	C20H33NO7
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	386750-22-7
Synonyms	Pristiq succinate hydrate, O-Desmethylvenlafaxine succinate hydrate
SMILES	CN(C)CC(C1=CC=C(C=C1)O)C2(CCCCC2)O.C(CC(=O)O)C(=O)O.O