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Dexrazoxane hydrochloride是一种心脏保护剂。作为EDTA的衍生物，右雷佐生与铁螯合，但其保护心脏的确切机制尚不清楚。该药物用于保护心脏免受蒽环类药物（如阿霉素）的心脏毒性副作用的影响。
靶点信息
| In vitro | DMSO | Warmed: 55 mg/mL (180.48 mM) | |
| Water | Warmed: 55 mg/mL (180.48 mM) | ||
| Ethanol | Insoluble | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 32.82 mL | 164.1 mL | 328.19 mL |
| 0.5 mM | 6.56 mL | 32.82 mL | 65.64 mL |
| 1 mM | 3.28 mL | 16.41 mL | 32.82 mL |
| 5 mM | 0.66 mL | 3.28 mL | 6.56 mL |
*The above data is based on the productmolecular weight 304.7. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A10300 |
|---|---|
| M. Wt | 304.7 |
| Formula | C11H17ClN4O4 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 149003-01-0 |
| Synonyms | Totect, ICRF-187, Zinecard, Cardioxane |
| SMILES | C[C@@H](CN1CC(=O)NC(=O)C1)N2CC(=O)NC(=O)C2.Cl |
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