Dihydroergotamine Mesylate

目录号: A17764

Serotonin receptors agonist

Dihydroergotamine Mesylate

Dihydroergotamine Mesylate Chemical Structure

CAS NO. 6190-39-2

Dihydroergotamine Mesylate, also known as DHE or Migranal, is an ergot alkaloid used to treat migraines. It has similar actions to the triptans, acting as an agonist to the serotonin receptors and causing vasoconstriction of the intracranial blood vessels, but also interacts centrally with dopamine and adrenergic receptors.

库存: 现货

规格 价格 数量
50 mg
¥ 420.00
100 mg
¥ 700.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Dihydroergotamine Mesylate, also known as DHE or Migranal, is an ergot alkaloid used to treat migraines. It has similar actions to the triptans, acting as an agonist to the serotonin receptors and causing vasoconstriction of the intracranial blood vessels, but also interacts centrally with dopamine and adrenergic receptors.
In vitro DMSO 99 mg/mL (145.63 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 14.71 mL 73.55 mL 147.11 mL
0.5 mM 2.94 mL 14.71 mL 29.42 mL
1 mM 1.47 mL 7.36 mL 14.71 mL
5 mM 0.29 mL 1.47 mL 2.94 mL

*The above data is based on the productmolecular weight 679.78. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A17764
作用机制 Agonist (激动剂)
M. Wt 679.78
Formula C34H41N5O8S
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 6190-39-2
Synonyms Dihydroergotamine Mesylate; DHE; Migranal;
SMILES O=C([C@@H](CN(C)[C@]1([H])C2)C[C@]1([H])C3=C4C2=CNC4=CC=C3)N[C@](C(N5[C@H]6CC7=CC=CC=C7)=O)(C)O[C@@]5(O)[C@]8([H])CCCN8C6=O.OS(=O)(C)=O

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