微信关注
Total item
Cart Subtotal
￥ 0.00 DNA Damage
-
HDACs/mTOR Inhibitor 1
Catalog No. A13462 HDACs/mTOR Inhibitor 1HDACs/mTOR Inhibitor 1 is a dual Histone Deacetylases (HDACs) and mammalian target of Rapamycin (mTOR) target inhibitor for treating hematologic malignancies. 了解更多 -
Sulforaphane
Catalog No. A21984 anti-cancer and anti-inflammatory activitiesSulforaphane activates Nrf2 and inhibits high glucose-induced progression of pancreatic cancer via AMPK dependent signaling. Sulforaphane has shown anti-cancer and anti-inflammatory activities. 了解更多 -
Olaparib (AZD2281)
Catalog No. A10111 PARP 抑制剂Olaparib (AZD2281)是聚ADP核糖聚合酶（PARP）的抑制剂，该酶是一种与DNA修复有关的酶。 了解更多 -
MK-4827 (Niraparib)
Catalog No. A11026 PARP 抑制剂MK-4827 (Niraparib)是一种新型有效的口服生物可利用的PARP-1和PARP-2抑制剂。 了解更多 -
PJ 34 hydrochloride
Catalog No. A12665 PARP 抑制剂PJ 34 hydrochloride是聚（ADP-核糖）聚合酶（PARP）（EC50 = 20 nM）的有效抑制剂。 了解更多 -
AG-014699 (Rucaparib)
Catalog No. A10045 PARP 抑制剂AG-014699 (Rucaparib)是一种PARP抑制剂，可抑制聚（ADP-核糖）聚合酶（PARP，后者是DNA修复中的关键酶。 无细胞试验中作用于PARP1的Ki为1.4 nM，对其余8个PARP位点也有结合亲和力。 了解更多 -
3-Aminobenzamide
Catalog No. A10475 PARP 抑制剂3-Aminobenzamide是一种新型PARP抑制剂，已知它通过抑制DNA损伤的修复使细胞在体外对辐射敏感。 了解更多 -
PJ34
Catalog No. A15215 -
AZD-2461
Catalog No. A12393 -
ME0328
Catalog No. A14309 -
Benzamide
Catalog No. A14371 -
BMN-673 8R,9S
Catalog No. A15024 -
4-HQN
Catalog No. A15370 -
BYK 204165
Catalog No. A15371 -
DR 2313
Catalog No. A15373 -
NU 1025
Catalog No. A15375 -
NVP-TNKS656
Catalog No. A15786 -
Talazoparib tosylate
Catalog No. A20238 PARP1/2 inhibitorTalazoparib tosylate (BMN 673ts) is a novel, potent and orally available PARP1/2 inhibitor with an IC50 of 0.57 nM for PARP1. 了解更多 -
PARP-2-IN-1
Catalog No. A20240 PARP-2 inhibitorPARP-2-IN-1 is a potent and selective PARP-2 inhibitor with an IC50 of 11.5 nM. 了解更多 -
Pamiparib
Catalog No. A17073 -
Rucaparib (Camsylate)
Catalog No. A18013 PARP 抑制剂Rucaparib Camsylate is an inhibitor of PARP with a Ki of 1.4 nM for PARP1, and also shows binding affinity to eight other PARP domains. 了解更多 -
PARP14 inhibitor H10
Catalog No. A18616 PARP14 抑制剂PARP14 inhibitor H10, compound H 10, is a selective inhibitor against PARP14 (IC50=490 nM), over other PARPs (??24 fold over PARP1). PARP14 inhibitor H10 induces caspase-3/7-mediated cell apoptosis. 了解更多 -
Niraparib tosylate
Catalog No. A16618 PARP1/PARP2 inhibitorNiraparib tosylate (MK-4827 tosylate) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with an IC50 of 3.8 and 2.1 nM, respectively. 了解更多 -
Niraparib hydrochloride
Catalog No. A18018 PARP1 and PARP2 inhibitorNiraparib hydrochloride (MK-4827 hydrochloride) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with IC50s of 3.8 and 2.1 nM, respectively. 了解更多 -
Niraparib R-enantiomer
Catalog No. A21880 PARP1 inhibitorNiraparib R-enantiomer (MK-4827 R-enantiomer) is an excellent PARP1 inhibitor with IC50 of 2.4 nM. 了解更多 -
Veliparib dihydrochloride
Catalog No. A21356 PARP inhibitorVeliparib dihydrochloride is a potent PARP inhibitor, inhibiting PARP1 and PARP2 with Kis of 5.2 and 2.9 nM, respectively. 了解更多
FILTER BY:
购物选项
- 分类
-
- HDAC (102)
- PARP (48)
- DNA-PK (14)
- Topoisomerase (75)
- Telomerase (6)
- ATM / ATR (21)
- DNA, RNA Synthesis (54)
- RNA/DNA Polymerase (21)
- DNA alkylator (8)
- Synthases / Synthetases (17)
- MTH1 (3)
- Sirtuins (30)
- IRE1 (2)
- DNA Stain (19)
- 作用机制
-
- Inhibitor (抑制剂) (305)
- Activator (激活剂) (11)
- Degrader (降解剂) (1)
- Substrate (底物) (2)
- 靶点
-
- DNA-PK (1)
- DNMT (1)
- EGFR (1)
- HD1 (2)
- HD2 (1)
- HDAC (21)
- HDAC1 (24)
- HDAC10 (4)
- HDAC11 (4)
- HDAC2 (15)
- HDAC3 (19)
- HDAC4 (6)
- HDAC5 (4)
- HDAC6 (23)
- HDAC7 (2)
- HDAC8 (9)
- HDAC9 (3)
- HER2 (1)
- Mdm2 (1)
- MdmX (1)
- NF-κB (1)
- p110α (2)
- p110β (2)
- p110γ (2)
- p110δ (2)
- p53 (2)
- PARP (13)
- PARP1 (10)
- PARP2 (4)
- PDE5 (1)
- SIRT1 (6)
- SIRT2 (5)
- SIRT3 (1)
- Sirtuin (1)
- Tankyrase-1 (5)
- Tankyrase-2 (8)
ADOOQ 产品质量保证
We promise all products to perform as described.