DNA Damage
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APY29
Catalog No. A13828 -
OSS-128167
Catalog No. A17048 -
Thiomyristoyl
Catalog No. A17166 -
EX 527 (Selisistat)
Catalog No. A10377 SIRT1 抑制剂EX 527 (Selisistat)是一种有效的选择性SIRT1 III类组蛋白脱乙酰基酶抑制剂,在无细胞分析中的IC50为38 nM。 了解更多 -
(S)-crizotinib
Catalog No. A14291 -
TH588
Catalog No. A15537 -
Raltitrexed (Tomudex)
Catalog No. A10776 DNA/RNA Synthesis 抑制剂Raltitrexed (Tomudex)是胸苷酸合酶的抑制剂,也是使用中最强的抗代谢物之一。 了解更多 -
Pneumocandin B0
Catalog No. A11113 β-1,3-Glucan Synthase 抑制剂Pneumocandin B0是脂肽家族的主要类似物,该脂肽家族是从几个不同属的几个物种中分离出来的,特别是隐孢子虫,Glarea和Pezicula。Pneumocandin B0是一种有效的抗真菌药,可通过抑制易感真菌细胞壁必不可少的成分β-(1,3)-D-葡聚糖的合成来发挥作用。 了解更多 -
Caspofungin
Catalog No. A13269 1,3-β-D-glucan synthase 抑制剂Caspofungin是一种抗真菌药。它用于帮助身体克服严重的真菌感染,包括念珠菌和曲霉菌感染。当其他药物(例如两性霉素B,伊曲康唑)失效时,也可用于治疗严重的真菌感染。 了解更多 -
Nolatrexed Dihydrochloride
Catalog No. A13261 -
Anidulafungin
Catalog No. A13436 glucan synthase 抑制剂Anidulafungin是一种半合成的环脂肽,属于棘白菌素类,于1995年报道,由礼来公司开发。Anidulafungin抑制β-(1,3)-D-葡聚糖的合成,β-(1,3)-D-葡聚糖是敏感真菌细胞壁的一个重要组成部分,在文献中被广泛引用,引用超过400篇。 了解更多 -
YM-53601
Catalog No. A13483 -
MF63
Catalog No. A11488 -
Genz-123346 free base
Catalog No. A15442 GL1 synthase 抑制剂Genz-123346 free base是GL1合酶的抑制剂,可阻止神经酰胺向GL1的转化。抑制GM1的IC50为14 nM。 了解更多 -
Buthionine Sulphoximine
Catalog No. A16202 γ-glutamylcysteine synthetase 抑制剂Buthionine Sulphoximine是一种γ-谷氨酰半胱氨酸合成酶抑制剂,可能用于治疗实体瘤。 了解更多 -
AN3365
Catalog No. A16329 -
Micafungin
Catalog No. A13270 1,3-β-D-glucan synthase 抑制剂米卡芬净(Mycamine; FK463)是一种棘皮菌素抗真菌药,可以抑制1,3-β-D-葡聚糖合酶。 了解更多 -
Eliglustat tartrate
Catalog No. A15466 Glucocerebroside synthase 抑制剂Eliglustat tartrate通常用作酒石酸盐,据信Eliglustat通过抑制葡萄糖基神经酰胺合酶起作用。 了解更多 -
Tenofovir (Viread)
Catalog No. A10908 HIV reverse transcriptase 抑制剂Tenofovir (Viread)属于一类称为核苷逆转录酶抑制剂(NRTIs)的药物。它通过减少血液中的HIV含量起作用。 了解更多 -
Abacavir sulfate
Catalog No. A11120 -
Abacavir
Catalog No. A11115 -
Delavirdine mesylate
Catalog No. A13274 -
Valaciclovir
Catalog No. A15270 -
Oncrasin 1
Catalog No. A15333 -
Mithramycin A
Catalog No. A15385 DNA/RNA polymerase 抑制剂Mithramycin A是一种抗生素DNA/RNA聚合酶和可与DNA结合的转录抑制剂,可促进TNF-α的表达。Fas-配体诱导细胞凋亡。 了解更多 -
Thiolutin
Catalog No. A15386 -
ACX-362E
Catalog No. A18560 DNA polymerase IIIC 抑制剂ACX-362E is an orally available DNA polymerase IIIC (pol IIIC) inhibitor, acts as an antimicrobial agent to treat Gram-positive infections, with a MIC50 of 2 μg/mL for C. difficile. ACX-362E displays very potent in vitro and in vivo activities against broad spectrum of C. difficile pathogens. 了解更多 -
Pseudouridimycin
Catalog No. A18520 RNA polymerase 抑制剂Pseudouridimycin (PUM), an antibiotic, is a selective bacterial RNA polymerase (RNAP) inhibitor. Pseudouridimycin is a C-nucleoside analogue that is effective against both Gram-negative and Gram-positive bacteria. 了解更多 -
DNA31
Catalog No. A18466 -
Dehydroaltenusin
Catalog No. A21804 eukaryotic DNA polymerase α inhibitorDehydroaltenusin is a small molecule selective inhibitor of eukaryotic DNA polymerase α, a type of antibiotic produced by a fungus with an IC50 value of 0.68 μM. 了解更多 -
T-705 (Favipiravir)
Catalog No. A11590 viral RNA polymerase 抑制剂T-705 (Favipiravir)是一种有效的选择性RNA-dependent RNA polymerase抑制剂,在体外和体内均表现出有效的抗流感病毒活性。 了解更多