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Dofetilide是一种III类抗心律不齐药物。Dofetilide的作用是选择性地阻断延迟整流器向外钾电流（Ikr）的快速成分。
靶点信息
| Potassium channel | ||||
| In vitro | DMSO | Warmed: 82 mg/mL (185.7 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.65 mL | 113.23 mL | 226.47 mL |
| 0.5 mM | 4.53 mL | 22.65 mL | 45.29 mL |
| 1 mM | 2.26 mL | 11.32 mL | 22.65 mL |
| 5 mM | 0.45 mL | 2.26 mL | 4.53 mL |
*The above data is based on the productmolecular weight 441.56. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A10328 |
|---|---|
| M. Wt | 441.56 |
| Formula | C19H27N3O5S2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 115256-11-6 |
| Synonyms | UK68798 |
| SMILES | CN(CCC1=CC=C(C=C1)NS(=O)(=O)C)CCOC2=CC=C(C=C2)NS(=O)(=O)C |
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