Dolasetron

Name: Dolasetron
SKU: A17595

目录号: A17595

5-HT3 receptor antagonist

Dolasetron Chemical Structure

CAS NO. 115956-12-2

Dolasetron is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy. Its main effect is to reduce the activity of the vagus nerve, which is a nerve that activates the vomiting center in the medulla oblongata. It does not have much antiemetic effect when symptoms are due to motion sickness.

库存：现货

规格	价格	数量
5 mg	￥ 840.00
10 mg	￥ 1,260.00
50 mg	￥ 3,850.00

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产品详情

生物活性

溶解度 *

In vitro	DMSO	61 mg/mL (188.05 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	30.83 mL	154.14 mL	308.29 mL
0.5 mM	6.17 mL	30.83 mL	61.66 mL
1 mM	3.08 mL	15.41 mL	30.83 mL
5 mM	0.62 mL	3.08 mL	6.17 mL

*The above data is based on the productmolecular weight 324.37. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A17595
作用机制	Antagonist (拮抗剂)
M. Wt	324.37
Formula	C19H20N2O3
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	115956-12-2
Synonyms	HSDB 7565; HSDB7565; HSDB-7565; Dolasetron; Dolasetronum
SMILES	O=C(C1=CNC2=C1C=CC=C2)OC(CC3N4C5)C[C@@]4([H])CC(C3)C5=O