E-4031 dihydrochloride

Name: E-4031 dihydrochloride
SKU: A12857

目录号: A12857

K+ channel blocker?

E-4031 dihydrochloride Chemical Structure

CAS NO. 113559-13-0

E-4031 dihydrochloride是KV11.1（hERG）通道的选择性阻滞剂；禁止快速延迟整流器K+电流（IKr）。

库存：现货

规格	价格	数量
10 mg	￥ 735.00
25 mg	￥ 1,680.00
50 mg	￥ 3,150.00
100 mg	￥ 5,950.00

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生物活性

E-4031 dihydrochloride是KV11.1（hERG）通道的选择性阻滞剂；禁止快速延迟整流器K+电流（IKr）。

溶解度 *

In vitro	DMSO	28 mg/mL (59.01 mM)
	Water	44 mg/mL (92.74 mM)
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.08 mL	105.39 mL	210.77 mL
0.5 mM	4.22 mL	21.08 mL	42.15 mL
1 mM	2.11 mL	10.54 mL	21.08 mL
5 mM	0.42 mL	2.11 mL	4.22 mL

*The above data is based on the productmolecular weight 474.44. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A12857
作用机制	Blocker (阻断剂)
M. Wt	474.44
Formula	C21H27N3O3S.2HCl
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	113559-13-0
Synonyms	E4031, E 4031
SMILES	CC1=NC(=CC=C1)CCN2CCC(CC2)C(=O)C3=CC=C(C=C3)NS(=O)(=O)C.Cl.Cl