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E7820是一种小分子芳香族磺酰胺衍生物,具有潜在的抗血管生成和抗肿瘤活性。E7820通过抑制整合素α2(一种在内皮细胞上表达的细胞粘附分子)来抑制血管生成。
In vitro | DMSO | 64 mg/mL (190.26 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 29.73 mL | 148.65 mL | 297.29 mL |
0.5 mM | 5.95 mL | 29.73 mL | 59.46 mL |
1 mM | 2.97 mL | 14.86 mL | 29.73 mL |
5 mM | 0.59 mL | 2.97 mL | 5.95 mL |
*The above data is based on the productmolecular weight 336.37. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A15456 |
---|---|
作用机制 | Inhibitor (抑制剂) |
M. Wt | 336.37 |
Formula | C17H12N4O2S |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 289483-69-8 |
Synonyms | E 7820, E-7820 |
SMILES | CC1=C2C(=CNC2=C(C=C1)NS(=O)(=O)C3=CC=CC(=C3)C#N)C#N |
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