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EG00229是第一个对Neuropilin-1和VEGF-A相互作用的小分子抑制剂，IC50抑制8 uM（125I-VEGF与PAE/NRP1细胞结合）。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 16.35 mL | 81.75 mL | 163.51 mL |
| 0.5 mM | 3.27 mL | 16.35 mL | 32.7 mL |
| 1 mM | 1.64 mL | 8.18 mL | 16.35 mL |
| 5 mM | 0.33 mL | 1.64 mL | 3.27 mL |
*The above data is based on the productmolecular weight 611.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A16237 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 611.6 |
| Formula | C19H20F3N7O7S3 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1210945-69-9 |
| Synonyms | EG 00229, EG-00229 |
| SMILES | C1=CC2=NSN=C2C(=C1)S(=O)(=O)NC3=C(SC=C3)C(=O)NC(CCCN=C(N)N)C(=O)O.C(=O)(C(F)(F)F)O |
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