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Eglumegad (LY354740) is a highly potent and selective group II (mGlu2/3) receptor agonist with IC50s of 5 and 24 nM on transfected human mGlu2 and mGlu3 receptors, respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 54 mL | 270.01 mL | 540.02 mL |
| 0.5 mM | 10.8 mL | 54 mL | 108 mL |
| 1 mM | 5.4 mL | 27 mL | 54 mL |
| 5 mM | 1.08 mL | 5.4 mL | 10.8 mL |
*The above data is based on the productmolecular weight 185.18. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A21005 |
|---|---|
| 作用机制 | Agonist (激动剂) |
| M. Wt | 185.18 |
| Formula | C8H11NO4 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 176199-48-7 |
| Synonyms | LY354740, LY 354740, LY-354740; Eglumetad |
| SMILES | OC([C@]1([C@]2([H])[C@@H](C(O)=O)[C@]2([H])CC1)N)=O |
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