EHop-016

Name: EHop-016
SKU: A12740

目录号: A12740

Rac GTPase Inhibitor

EHop-016 Chemical Structure

CAS NO. 1380432-32-5

EHop-016 is a potent and specific inhibitor of Rac1 and Rac3 GTPase activity that inhibits Vav2 interaction with Rac, Rac-activated PAK1, lamellipodia formation, and cell migration.

库存：现货

规格	价格	数量
10 mg	￥ 490.00
25 mg	￥ 1,050.00
50 mg	￥ 1,750.00
100 mg	￥ 2,800.00
10mM * 1mL in DMSO	￥ 623.00

大包装询价

或

添加到收藏

产品仅用于科学研究，不针对患者销售，望谅解.

产品详情

生物活性

EHop-016 is a potent and specific inhibitor of Rac1 and Rac3 GTPase activity that inhibits Vav2 interaction with Rac, Rac-activated PAK1, lamellipodia formation, and cell migration.

靶点信息

Rac1 (MDA-MB-435, MDA-MB-231 cells)
1.1 μM

溶解度 *

In vitro (25°C)	DMSO	83 mg/mL (192.77 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	2% DMSO+30% PEG 300+5% Tween 80+ddH2O	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.23 mL	116.13 mL	232.26 mL
0.5 mM	4.65 mL	23.23 mL	46.45 mL
1 mM	2.32 mL	11.61 mL	23.23 mL
5 mM	0.46 mL	2.32 mL	4.65 mL

*The above data is based on the productmolecular weight 430.55. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A12740
作用机制	Inhibitor (抑制剂)
M. Wt	430.55
Formula	C25H30N6O
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1380432-32-5
Synonyms	EHop016
SMILES	CCN1C2=C(C=C(C=C2)NC3=NC(=NC=C3)NCCCN4CCOCC4)C5=CC=CC=C51