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Elacestrant (RAD1901) is an orally available selective estrogen receptor degrader (SERD) with IC50s of 48 and 870 nM for ERα and ERβ, respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.8 mL | 109.02 mL | 218.04 mL |
| 0.5 mM | 4.36 mL | 21.8 mL | 43.61 mL |
| 1 mM | 2.18 mL | 10.9 mL | 21.8 mL |
| 5 mM | 0.44 mL | 2.18 mL | 4.36 mL |
*The above data is based on the productmolecular weight 458.63. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A12244 |
|---|---|
| 作用机制 | Degrader (降解剂) |
| M. Wt | 458.63 |
| Formula | C30H38N2O2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 722533-56-4 |
| Synonyms | RAD1901, RAD 1901, RAD-1901 |
| SMILES | OC1=CC=C2C[C@H](C3=CC=C(OC)C=C3N(CC)CC4=CC=C(CCNCC)C=C4)CCC2=C1 |
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