Endocrinology / Hormones
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AZD2906
Catalog No. A18936 glucocorticoid receptor agonistAZD2906 is a selective glucocorticoid receptor (GR) agonist, increases micronucleated immature erythrocytes in the bone marrow of rats. AZD2906 shows IC50s of 2.2, 0.3, 41.6 and 7.5 nM at GR in human, rat PBMC and human, rat whole blood, respectively. 了解更多 -
Betamethasone acibutate
Catalog No. A18697 glucocorticoidBetamethasone acibutate, derives from Betamethasone, is an acetate ester. Betamethasone acibutate is a glucocorticoid. 了解更多 -
Glucocorticoid receptor agonist
Catalog No. A11431 Glucocorticoid receptor agonistGlucocorticoid receptor agonist is a potent Glucocorticoid receptor agonist. 了解更多 -
Dexamethasone acetate
Catalog No. A16494 glucocorticoid receptor agonistDexamethasone acetate (Dexamethasone 21-acetate) is a glucocorticoid receptor agonist. 了解更多 -
Beclometasone dipropionate
Catalog No. A17254 glucocorticoid agonistBeclometasone dipropionate is a potent glucocorticoid agonist; it is a prodrug of the free form, beclometasone. 了解更多 -
Fosdagrocorat
Catalog No. A21303 dissociated glucocorticoid receptor agonistFosdagrocorat (PF-04171327) is a dissociated glucocorticoid receptor agonist. 了解更多 -
Dagrocorat
Catalog No. A21312 glucocorticoid receptor agonistDagrocorat (PF-00251802) is a novel and dissociated glucocorticoid receptor agonist. 了解更多 -
(S)-Mapracorat
Catalog No. A21528 glucocorticoid receptor agonist(S)-Mapracorat is a selective and less active glucocorticoid receptor agonist. 了解更多 -
Mapracorat
Catalog No. A21953 glucocorticoid receptor agonistMapracorat is a novel non-steroidal selective glucocorticoid receptor agonist. 了解更多 -
Anastrozole
Catalog No. A10075 Aromatase 抑制剂Anastrozole是第三代非甾体选择性芳香化酶抑制剂。与其他芳香酶抑制剂相比,它可能具有更高的选择性,没有任何内在的内分泌作用,并且对肾上腺类固醇的合成也没有明显的作用。 了解更多 -
Exemestane
Catalog No. A10378 -
Alpha-Naphthoflavone
Catalog No. A18474 aromatase inhibitorAlpha-Naphthoflavone is a synthetic flavonoid, acts as a potent and competitive aromatase inhibitor with an IC50 and a Ki of 0.5 and 0.2 μM, respectively. 了解更多 -
Fadrozole hydrochloride
Catalog No. A21258 Aromatase inhibitorFadrozole hydrochloride is a potent, selective and nonsteroidal inhibitor of aromatase with an IC50 of 6.4 nM. 了解更多 -
Aliskiren hemifumarate
Catalog No. A11123 -
Candesartan (Atacand)
Catalog No. A10175 RAAS 拮抗剂Candesartan (Atacand)是一种血管紧张素受体阻滞剂(也称为血管紧张素II受体拮抗剂或AIIRA)。 了解更多 -
Benazepril HCl
Catalog No. A10123 -
Clinofibrate
Catalog No. A11184 HMG-CoA Reductase 抑制剂Clinofibrate是一种脂质清除剂,似乎可以改变脂质代谢,减少类固醇诱导的骨细胞内脂质堆积。它还可以有效降低血浆纤维蛋白原水平。抑制hydroxymethylglutaryl coenzyme A reductase (HMGCR)(羟甲基戊二酰辅酶A还原酶),IC50为0.47 mM。 了解更多 -
Rosuvastatin
Catalog No. A11122 -
Irbesartan (Avapro)
Catalog No. A10477 -
Aliskiren (CGP 60536)
Catalog No. A11616 -
Candesartan cilexetil (Atacand)
Catalog No. A10176 Candesartan Cilexetil一种特异性的,非肽类血管生成素II受体(ATR)拮抗剂,也是Candesartan的前体药物,是ATR拮抗剂 了解更多 -
Quinapril hydrochloride
Catalog No. A11736 Quinapril hydrochloride是一种催化血管紧张素II从其前体血管紧张素I形成的酶。 了解更多 -
Moexipril hydrochloride
Catalog No. A11745 Moexipril hydrochloride是一种有效的口服活性非巯基血管紧张素转换酶抑制剂(ACE),可作用于高血压和充血性心力衰竭。 了解更多 -
Cilazapril monohydrate
Catalog No. A11747 -
Enalapril maleate
Catalog No. A10350 -
Enalaprilat dihydrate
Catalog No. A10351 -
PD 123319 ditrifluoroacetate
Catalog No. A13201 angiotensin AT2 receptor 拮抗剂PD 123319 ditrifluoroacetate是一种有效的,选择性的非肽血管紧张素AT2受体拮抗剂。大鼠肾上腺组织和大脑的IC50值分别为34和210 nM。 了解更多 -
LCZ696 (Valsartan)
Catalog No. A14206 angiotensin receptor-neprilysin 抑制剂LCZ696 (Valsartan)是一种生物利用型双效血管紧张素受体-中性溶血素抑制剂(ARNi),用于治疗高血压和心力衰竭。 了解更多 -
Captopril disulfide
Catalog No. A13521 LTA4 hydrolase 抑制剂Captopril disulfide是LTA4水解酶的可逆竞争性抑制剂(IC50 = 11 M)。Captopril已被证明是血管紧张素转化酶-1(ACE1)的一种,而不是ACE2(IC50 = 22 nM)。 了解更多 -
Angiotensin I (human, mouse, rat)
Catalog No. A14859 Angiotensin I (human,mouse,rat)是由肾素对血管紧张素原的作用形成的。 了解更多 -
Angiotensin (1-7)
Catalog No. A14862 Angiotensin (1-7)是一种内源性肽片段,可以分别通过内切肽酶或羧肽酶从Ang I或Ang II产生。 了解更多 -
Angiotensin II
Catalog No. A14863 Angiotensin II是一种八肽激素,在心血管稳态中起着核心作用。 了解更多 -
Angiotensin III (human, mouse)
Catalog No. A14864 Angiotensin III (human,mouse)是在血管紧张素II的N末端裂解形成的六肽,血管紧张素II是位于红细胞和大多数组织血管床中的血管紧张素酶在肾素-血管紧张素-醛固酮(RAAS)系统中的关键因素。 了解更多 -
Angiotensin 1/2 (1-9)
Catalog No. A14873 Angiotensin 1/2 (1-9)是一种肽(ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS),包含从血管紧张素I/II肽转换而来的氨基酸1-9。 了解更多 -
Acetyl Angiotensinogen (1-14), porcine
Catalog No. A14883 Acetyl Angiotensinogen (1-14), porcine血管紧张素原基因编码的蛋白质被称为血管紧张素原或血管紧张素原的前体。 了解更多 -
Angiotensin 1/2 (1-5)
Catalog No. A14886 Angiotensin 1/2 (1-5)是一种包含氨基酸1-5的肽,是从血管紧张素I/II转化而来的。 了解更多 -
Angiotensin 1/2 (1-6)
Catalog No. A14887 Angiotensin 1/2 (1-6)是一种包含氨基酸1-6的肽,是从血管紧张素I/II肽转化而来的。 了解更多 -
Angiotensin 1/2 + A (2 - 8)
Catalog No. A14888 Angiotensin 1/2 + A (2 - 8)有效的内源性血管收缩肽;血管紧张素(Ang)的衍生物II。 了解更多 -
VTP-27999 2,2,2-trifluoroacetate
Catalog No. A15281 -
Spinorphin
Catalog No. A15314 -
EXP-3174
Catalog No. A15451 -
MLN-4760
Catalog No. A16884 -
Eprosartan
Catalog No. A11121 -
Olmesartan (RNH6270, CS-088)
Catalog No. A10670 Olmesartan (RNH6270,CS-088)是一种用于治疗高血压的血管紧张素II受体拮抗剂。 了解更多 -
Olmesartan medoxomil
Catalog No. A11615 Olmesartan medoxomil是一种用于治疗高血压的血管紧张素II受体拮抗剂。奥美沙坦通过阻断血管紧张素II与血管肌肉AT1受体的结合来发挥作用。通过阻断结合而不是血管紧张素II的合成,奥美沙坦抑制了对肾素分泌的负面调节反馈。 了解更多 -
Azilsartan (TAK-536)
Catalog No. A11775